(Q35525691)

8 August 2017

title

Critical role for Syk in responses to vascular injury (English)

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8 August 2017

Patrick Andre

1

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8 August 2017

Toshifumi Morooka

2

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8 August 2017

Derek Sim

3

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8 August 2017

Keith Abe

4

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8 August 2017

Clifford Lowell

5

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8 August 2017

Nisha Nanda

6

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8 August 2017

Suzanne Delaney

7

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8 August 2017

Gail Siu

8

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8 August 2017

Yibing Yan

9

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8 August 2017

Stan Hollenbach

10

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8 August 2017

Anjali Pandey

11

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8 August 2017

Huiyun Gao

12

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8 August 2017

Yunmei Wang

13

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8 August 2017

Kohsuke Nakajima

14

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8 August 2017

Sahil A Parikh

15

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8 August 2017

Can Shi

16

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8 August 2017

David Phillips

17

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8 August 2017

Whyte Owen

18

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8 August 2017

Uma Sinha

19

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8 August 2017

Daniel I Simon

20

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8 August 2017

language of work or name

English

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publication date

31 August 2011

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8 August 2017

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8 August 2017

volume

118

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8 August 2017

issue

18

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8 August 2017

page(s)

5000-5010

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Spleen tyrosine kinase inhibition in the treatment of autoimmune, allergic and autoinflammatory diseases

8 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

The SYK tyrosine kinase: a crucial player in diverse biological functions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

12 July 2018

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Evaluation of the physiological significance of botrocetin/ von Willebrand factor in vitro signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Rev

12 July 2018

1 reference

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In vivo thrombus formation in murine models

12 July 2018

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R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

12 July 2018

1 reference

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Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.

12 July 2018

1 reference

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GPVI and integrin alphaIIb beta3 signaling in platelets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Defective thrombus formation in mice lacking coagulation factor XII

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Platelet adhesion signalling and the regulation of thrombus formation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease-activated receptor 1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Soluble CD40 ligand induces β 3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Decreased neointimal formation in Mac-1(-/-) mice reveals a role for inflammation in vascular repair after angioplasty

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

A MAC-1 attack: integrin functions directly challenged in knockout mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Syk tyrosine kinase required for mouse viability and B-cell development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (updating the 200

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Platelets undergo phosphorylation of Syk at Y525/526 and Y352 in response to pathophysiological shear stress.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Spleen tyrosine kinase participates in Src-mediated migration and proliferation by PDGF-BB in rat aortic smooth muscle cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Adverse impact of bleeding on prognosis in patients with acute coronary syndromes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Lipid raft adhesion receptors and Syk regulate selectin-dependent rolling under flow conditions.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Pathological shear stress directly regulates platelet alphaIIbbeta3 signaling.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Dependence of platelet thrombus stability on sustained glycoprotein IIb/IIIa activation through adenosine 5'-diphosphate receptor stimulation and cyclic calcium signaling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Leukocyte engagement of platelet glycoprotein Ibalpha via the integrin Mac-1 is critical for the biological response to vascular injury

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Syk is required for integrin signaling in neutrophils

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Role of PSGL-1 binding to selectins in leukocyte recruitment

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208305

Mouse model of femoral artery denudation injury associated with the rapid accumulation of adhesion molecules on the luminal surface and recruitment of neutrophils

15 November 2018

1 reference

12 December 2020

Inflammation and thrombosis: the clot thickens

1 reference

12 December 2020

Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation

1 reference

12 December 2020

In vivo models of platelet function and thrombosis: study of real-time thrombus formation

1 reference

12 December 2020

Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in platelets

1 reference

12 December 2020

Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency

1 reference

12 December 2020

Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets

1 reference

12 December 2020

Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3

1 reference

12 December 2020

Tyrosine Phosphorylation of the Fc Receptor γ-Chain in Collagen-stimulated Platelets

1 reference

12 December 2020

Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18

1 reference

12 December 2020

The alpha2beta1 integrin is a necessary co-receptor for collagen-induced activation of Syk and the subsequent phosphorylation of phospholipase Cgamma2 in platelets

1 reference

12 December 2020

10.1182/BLOOD-2011-06-360743

Identifiers

DOI

1 reference

8 August 2017

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8 August 2017

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