(Q35535893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12728163%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12728163%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

1

1 reference

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3 November 2019

Sheila Barton

2

1 reference

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3 November 2019

Shu Ye

9

1 reference

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3 November 2019

John W. Holloway

10

1 reference

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3 November 2019

author name string

S Rorke

3

1 reference

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3 November 2019

B Beghé

4

1 reference

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3 November 2019

B Hayward

5

1 reference

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3 November 2019

P Van Eerdewegh

6

1 reference

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3 November 2019

T Keith

7

1 reference

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3 November 2019

J B Clough

8

1 reference

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3 November 2019

A P Sampson

11

1 reference

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3 November 2019

S T Holgate

12

1 reference

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3 November 2019

language of work or name

English

0 references

publication date

1 May 2003

1 reference

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3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12728163%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

58

1 reference

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3 November 2019

issue

5

1 reference

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3 November 2019

page(s)

417-424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12728163%20AND%20SRC:MED&resulttype=core&format=json

Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast

3 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Sp1 and Sp3 function as key regulators of leukotriene C(4) synthase gene expression in the monocyte-like cell line, THP-1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Cell-specific transcription of leukotriene C(4) synthase involves a Kruppel-like transcription factor and Sp1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Genetic mechanisms in aspirin-induced asthma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Aspirin-induced asthma: advances in pathogenesis and management

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

TGF-beta increases leukotriene C4 synthase expression in the monocyte-like cell line, THP-1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Investigation into the increase in hay fever and eczema at age 16 observed between the 1958 and 1970 British birth cohorts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Molecular cloning of the human leukotriene C4 synthase gene and assignment to chromosome 5q35

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Single-well genotyping of diallelic sequence variations by a two-color ELISA-based oligonucleotide ligation assay

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Ultrarapid mutation detection by multiplex, solid-phase chemical cleavage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Molecular cloning of the gene for human leukotriene C4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Receptor-mediated regulation of leukotriene C4 synthase activity in human platelets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Molecular cloning and expression of human leukotriene-C4 synthase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Cysteinyl leukotrienes in asthma: old mediators up to new tricks

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Mechanism of aspirin-induced asthma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1746660

Post-transcriptional regulation of LTC4 synthase activity by retinoic acid in rat basophilic leukemia cells

26 September 2018

1 reference

12 December 2020

Polymorphism at the glutathione S-transferase GSTP1 locus. A new marker for bronchial hyperresponsiveness and asthma

1 reference

12 December 2020

Comparison of PD20 with two alternative measures of response to histamine challenge in epidemiological studies.

1 reference

12 December 2020

Activation of protein kinase C down-regulates leukotriene C4 synthase activity and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cells

1 reference

12 December 2020

Interleukin-3 regulates development of the 5-lipoxygenase/leukotriene C4 synthase pathway in mouse mast cells

1 reference

12 December 2020

Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999

1 reference

12 December 2020

Identifiers

DOI

10.1136/THORAX.58.5.417

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12728163%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12728163%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

12728163

1 reference