(Q35538634)

8 August 2017

1 reference

title

Antiarrhythmic drug target choices and screening (English)

1 reference

8 August 2017

Antiarrhythmic Drug Target Choices and Screening (English)

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Cardiology and cardiovascular medicine

12 March 2024

main subject

drug screening

0 references

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

12 March 2024

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

12 March 2024

author name string

Michael C. Sanguinetti

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500332

12 March 2024

Paul B. Bennett

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500332

12 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14500332

12 March 2024

publication date

1 September 2003

1 reference

8 August 2017

19 September 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14500332

12 March 2024

1 reference

8 August 2017

volume

93

1 reference

8 August 2017

issue

6

1 reference

8 August 2017

page(s)

491-499

1 reference

The experimental basis for the choice of an anti-arrhythmic drug

8 August 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Relevance of cellular to clinical electrophysiology in interpreting antiarrhythmic drug action

12 March 2024

2

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial

12 March 2024

5

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction. The SWORD Investigators. Survival With Oral d-Sotalol.

12 March 2024

6

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Dofetilide in patients with congestive heart failure and left ventricular dysfunction. Danish Investigations of Arrhythmia and Mortality on Dofetilide Study Group

12 March 2024

7

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT. European Myocardial Infarct Amiodarone Trial Investigators

12 March 2024

8

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Effect of propranolol in patients with myocardial infarction and ventricular arrhythmia

12 March 2024

9

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators

12 March 2024

10

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias

12 March 2024

11

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Focal modification of electrical conduction in the heart by viral gene transfer

12 March 2024

12

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Biological pacemaker created by gene transfer

12 March 2024

14

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III. The "leading circle" concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle

12 March 2024

15

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Mechanisms underlying ventricular tachycardia and its transition to ventricular fibrillation in the structurally normal heart.

12 March 2024

16

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Stationary and drifting spiral waves of excitation in isolated cardiac muscle

12 March 2024

17

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Mechanisms of Cardiac Fibrillation

12 March 2024

18

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

A novel approach to identifying antiarrhythmic drug targets

12 March 2024

19

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Preventing ventricular fibrillation by flattening cardiac restitution

12 March 2024

21

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Suppression of Lethal Ischemic Ventricular Arrhythmias by the Class III Agent E4031 in a Canine Model of Previous Myocardial Infarction

12 March 2024

23

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

12 March 2024

Pharmacological Reviews

25

40

219

1988

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Triggered activity in the heart: cellular mechanisms of early after-depolarizations

12 March 2024

26

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

12 March 2024

30

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Mutations in the hminK gene cause long QT syndrome and suppress IKs function

12 March 2024

31

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Molecular basis of the long-QT syndrome associated with deafness

12 March 2024

32

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.

12 March 2024

33

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia

12 March 2024

35

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Effects of the antiarrhythmic agent EGIS-7229 (S 21407) on calcium and potassium currents in canine ventricular cardiomyocytes

12 March 2024

36

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

12 March 2024

Molecular Pharmacology

37

53

220

1998

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites.

12 March 2024

38

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels

12 March 2024

39

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Saxitoxin is a gating modifier of HERG K+ channels

12 March 2024

40

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs

12 March 2024

41

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Flip the tip: an automated, high quality, cost-effective patch clamp screen

12 March 2024

42

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Micromolded PDMS planar electrode allows patch clamp electrical recordings from cells.

12 March 2024

43

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Newer developments in the management of atrial fibrillation.

12 March 2024

44

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

The molecular and ionic specificity of antiarrhythmic drug actions

12 March 2024

45

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Atrial electrophysiological remodeling caused by rapid atrial activation: underlying mechanisms and clinical relevance to atrial fibrillation

12 March 2024

46

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Amlodipine, but not verapamil or nifedipine, dilates rabbit femoral artery largely through a nitric oxide- and kinin-dependent mechanism.

12 March 2024

51

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Nifedipine facilitates neurotransmitter release independently of calcium channels

12 March 2024

52

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A.

12 March 2024

53

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway

12 March 2024

54

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Interactions with PDZ proteins are required for L-type calcium channels to activate cAMP response element-binding protein-dependent gene expression.

12 March 2024

55

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Control of recruitment and transcription-activating function of CBP determines gene regulation by NMDA receptors and L-type calcium channels

12 March 2024

56

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons

12 March 2024

57

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clamp

12 March 2024

58

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Expression of T- and L-type calcium channel mRNA in murine sinoatrial node

12 March 2024

59

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Molecular physiology of low-voltage-activated t-type calcium channels

12 March 2024

60

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Shrinkage-induced activation of Na+/H+ exchange in rat renal mesangial cells

12 March 2024

61

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

T-type Ca2+ channels and pharmacological blockade: potential pathophysiological relevance

12 March 2024

64

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits

12 March 2024

66

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Purified, reconstituted cardiac Ca2+-ATPase is regulated by phospholamban but not by direct phosphorylation with Ca2+/calmodulin-dependent protein kinase

12 March 2024

67

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle

12 March 2024

68

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

American Journal of Physiology

12 March 2024

69

276

H2168

1999

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

The effect of flunarizine and ryanodine on acquired torsades de pointes arrhythmias in the intact canine heart

12 March 2024

70

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Mechanisms underlying early and delayed afterdepolarizations induced by catecholamines

12 March 2024

72

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

12 March 2024

74

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Beta-blockers and sudden cardiac death.

12 March 2024

75

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

12 March 2024

77

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

12 March 2024

78

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Depressed ryanodine receptor activity increases variability and duration of the systolic Ca2+ transient in rat ventricular myocytes.

12 March 2024

79

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Alternans goes subcellular: a "disease" of the ryanodine receptor?

12 March 2024

80

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5.

12 March 2024

81

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Cloning and characterization of a Kv1.5 delayed rectifier K+ channel from vascular and visceral smooth muscles

12 March 2024

82

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

High throughput ion-channel pharmacology: planar-array-based voltage clamp

12 March 2024

83

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

Ionworks HT: a new high-throughput electrophysiology measurement platform.

12 March 2024

84

1 reference

https://api.crossref.org/works/10.1161/01.RES.0000091829.63501.A8

12 March 2024

Identifiers

1 reference

8 August 2017

1 reference