(Q35548663)

8 August 2017

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title

Tryptophan depletion and HIV infection: a metabolic link to pathogenesis (English)

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8 August 2017

Michael F Murray

1

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8 August 2017

publication date

1 October 2003

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Lancet Infectious Diseases

8 August 2017

published in

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8 August 2017

volume

3

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8 August 2017

issue

10

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8 August 2017

page(s)

644-652

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Tryptophan Nutrition and Metabolism: An Overview

8 August 2017

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7 January 2021

Increased plasma tryptophan in HIV-infected patients treated with pharmacologic doses of nicotinamide

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7 January 2021

Tryptophan degradation in patients infected by human immunodeficiency virus

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7 January 2021

Indole amine deficiency in blood and cerebrospinal fluid from patients with human immunodeficiency virus infection

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7 January 2021

Immune activation and decreased tryptophan in patients with HIV-1 infection.

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7 January 2021

Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection

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7 January 2021

Nocturnal sleep EEG in patients with HIV infection.

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7 January 2021

Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients

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7 January 2021

Tryptophan concentrations increase in cerebrospinal fluid and blood after zidovudine treatment in patients with HIV type 1 infection

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7 January 2021

Decreased plasma ratio of tryptophan to competing large neutral amino acids in human immunodeficiency virus type 1 infected subjects: possible implications for development of neuro-psychiatric disorders

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7 January 2021

Threonine and methionine are limiting amino acids for protein synthesis in patients with AIDS.

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7 January 2021

Parallel decrease in neurotoxin quinolinic acid and soluble tumor necrosis factor receptor p75 in serum during highly active antiretroviral therapy of HIV type 1 disease

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7 January 2021

Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection

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7 January 2021

Quantitative aspects of tryptophan metabolism in humans and other species: a review

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7 January 2021

Enzymic formation of D-kynurenine from D-tryptophan.

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7 January 2021

Regulation of Pyridine Nucleotide Coenzyme Metabolism

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7 January 2021

Energy expenditure and wasting in human immunodeficiency virus infection

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https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Micronutrient profiles in HIV-1-infected heterosexual adults

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7 January 2021

Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus

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7 January 2021

Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

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7 January 2021

Induction of pulmonary indoleamine 2,3-dioxygenase by interferon

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7 January 2021

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

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7 January 2021

An interferon-induced protein with release factor activity is a tryptophanyl-tRNA synthetase

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7 January 2021

Kynurenine enzymatic pathway in human monocytes-macrophages. Effect of interferon-gamma activation

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7 January 2021

Expression of indoleamine 2,3-dioxygenase, tryptophan degradation, and kynurenine formation during in vivo infection with Toxoplasma gondii: induction by endogenous gamma interferon and requirement of interferon regulatory factor 1.

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7 January 2021

L-tryptophan-L-kynurenine pathway metabolism accelerated by Toxoplasma gondii infection is abolished in gamma interferon-gene-deficient mice: cross-regulation between inducible nitric oxide synthase and indoleamine-2,3-dioxygenase

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7 January 2021

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan

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7 January 2021

Interferon-gamma suppresses the growth of Toxoplasma gondii in human fibroblasts through starvation for tryptophan

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7 January 2021

Prevention of allogeneic fetal rejection by tryptophan catabolism

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7 January 2021

Metabolism of nicotinic acid in pregnancy

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7 January 2021

The Vanderbilt cooperative study of maternal and infant nutrition. IV. Dietary, laboratory and physical findings in 2,129 delivered pregnancies

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7 January 2021

Extinguishing maternal immune responses during pregnancy: implications for immunosuppression

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7 January 2021

Decreased plasma tryptophan in pregnancy

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https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Longitudinal study of tryptophan degradation during and after pregnancy

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7 January 2021

Immunological tolerance of the human fetus

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7 January 2021

Proliferative responses to recall antigens are associated with pregnancy outcome in women with a history of recurrent spontaneous abortion

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7 January 2021

How useful is the in vitro expansion of fetal CD34+ progenitor cells from maternal blood samples for diagnostic purposes?

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Increased quinolinate immunoreactivity in the peripheral blood monocytes/macrophages from SIV-infected monkeys

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7 January 2021

Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Metabolic disturbances and wasting in the acquired immunodeficiency syndrome

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https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Increased glutamate in CSF and plasma of patients with HIV dementia

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https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Tryptophan-niacin relationships in pregnancy

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7 January 2021

THE EFFECT OF VITAMIN SUPPLEMENTATION ON THE URINARY EXCRETION OF TRYPTOPHAN METABOLITES BY PREGNANT WOMEN

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7 January 2021

CTLA-4-Ig regulates tryptophan catabolism in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Frontal cortex indoleamine-2,3-dioxygenase activity is increased in HIV-1-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Sources of the neurotoxin quinolinic acid in the brain of HIV-1-infected patients and retrovirus-infected macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Increased resting energy expenditure in human immunodeficiency virus-infected men.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

The metabolic puzzle during the evolution of HIV infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Interferon-gamma has immunomodulatory effects with minor endocrine and metabolic effects in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Brain serotonin content: physiological dependence on plasma tryptophan levels.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Tryptophan and lysine metabolism in alpha-aminoadipic aciduria.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Tryptophan availability selectively limits NO-synthase induction in macrophages.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Effects of micronutrient intake on survival in human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

Dietary micronutrient intake and risk of progression to acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus type 1 (HIV-1)-infected homosexual men.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2803%2900773-4

7 January 2021

10.1016/S1473-3099(03)00773-4

Identifiers

DOI

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8 August 2017

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