(Q35550628)

8 August 2017

Sequence divergence, functional constraint, and selection in protein evolution (English)

1 reference

8 August 2017

Sequence Divergence, Functional Constraint, and Selection in Protein Evolution (English)

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

18 March 2024

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14527302

18 March 2024

genetic selection

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14527302

18 March 2024

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

18 March 2024

author name string

Chung-I Wu

2

1 reference

8 August 2017

Justin C. Fay

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14527302

18 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14527302

18 March 2024

publication date

1 January 2003

1 reference

Annual Review of Genomics and Human Genetics

8 August 2017

1 reference

8 August 2017

4

1 reference

8 August 2017

213-235

1 reference

Linkage disequilibrium in the human genome

8 August 2017

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1038/35075590

Slightly Deleterious Mutant Substitutions in Evolution

30 October 2021

1 reference

4 November 2023

https://opencitations.net/index/coci/api/v1/citations/10.1038/246096A0

Evolutionary Rate at the Molecular Level

1 reference

4 November 2023

https://opencitations.net/index/coci/api/v1/citations/10.1038/217624A0

Gene expression and molecular evolution

2

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Accuracy and power of the likelihood ratio test in detecting adaptive molecular evolution

18 March 2024

3

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Accuracy and power of bayes prediction of amino acid sites under positive selection

18 March 2024

4

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Positive and negative selection in the DAZ gene family

18 March 2024

5

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Inferring functional constraints and divergence in protein families using 3D mapping of phylogenetic information.

18 March 2024

6

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data.

18 March 2024

7

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The cost of inbreeding in Arabidopsis.

18 March 2024

8

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Characterization of single-nucleotide polymorphisms in coding regions of human genes

18 March 2024

10

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation

18 March 2024

11

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

An algorithm for detecting directional and non-directional positive selection, neutrality and negative selection in protein coding DNA sequences.

18 March 2024

12

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Evolution of transcription factor binding sites in Mammalian gene regulatory regions: conservation and turnover

18 March 2024

14

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Large-scale search for genes on which positive selection may operate.

18 March 2024

16

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Quantifying the Slightly Deleterious Mutation Model of Molecular Evolution

18 March 2024

18

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The neutral theory in the genomic era.

18 March 2024

20

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Testing the neutral theory of molecular evolution with genomic data from Drosophila.

18 March 2024

22

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The genetical theory of natural selection

18 March 2024

23

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Long term trends in the evolution of H(3) HA1 human influenza type A

18 March 2024

24

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Positive Darwinian evolution in human influenza A viruses

18 March 2024

25

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

An improved method for determining codon variability in a gene and its application to the rate of fixation of mutations in evolution

18 March 2024

26

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The structure of haplotype blocks in the human genome

18 March 2024

28

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

A nonhyperthermophilic common ancestor to extant life forms.

18 March 2024

29

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Molecular Biology and Evolution

18 March 2024

30

6

636

Gillespie J

1989

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Statistical tests of gamma-distributed rate heterogeneity in models of sequence evolution in phylogenetics

18 March 2024

31

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Molecular Biology and Evolution

18 March 2024

32

11

725

Goldman N

1994

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Amino acid difference formula to help explain protein evolution

18 March 2024

33

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Amino acid composition and the evolutionary rates of protein-coding genes.

18 March 2024

34

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Maximum-likelihood approach for gene family evolution under functional divergence.

18 March 2024

35

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Densities, length proportions, and other distributional features of repetitive sequences in the human genome estimated from 430 megabases of genomic sequence

18 March 2024

36

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays

18 March 2024

37

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

A Mathematical Theory of Natural and Artificial Selection, Part V: Selection and Mutation

18 March 2024

38

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

18 March 2024

39

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Constant relative rate of protein evolution and detection of functional diversification among bacterial, archaeal and eukaryotic proteins

18 March 2024

41

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Microevolutionary genomics of bacteria

18 March 2024

42

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Evolution of Protein Molecules

18 March 2024

43

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The average number of generations until extinction of an individual mutant gene in a finite population

18 March 2024

48

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

18 March 2024

Non-Darwinian Evolution

49

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Direct estimates of human per nucleotide mutation rates at 20 loci causing Mendelian diseases

18 March 2024

50

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Dobzhansky-Muller incompatibilities in protein evolution

18 March 2024

51

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Selection in the evolution of gene duplications

18 March 2024

52

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

A molecular timescale for vertebrate evolution

18 March 2024

53

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura

18 March 2024

54

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Evolutionary parameters of the transcribed mammalian genome: an analysis of 2,820 orthologous rodent and human sequences

18 March 2024

58

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Adaptive protein evolution at the Adh locus in Drosophila

18 March 2024

59

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Episodic adaptive evolution of primate lysozymes.

18 March 2024

61

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The K(A)/K(S) ratio test for assessing the protein-coding potential of genomic regions: an empirical and simulation study

18 March 2024

62

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Accounting for human polymorphisms predicted to affect protein function

18 March 2024

63

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Statistical analyses of Drosophila and human protein polymorphisms

18 March 2024

67

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Synonymous and nonsynonymous substitutions in mammalian genes and the nearly neutral theory

18 March 2024

68

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Role of random genetic drift in the evolution of interactive systems

18 March 2024

69

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Expected relationship between the silent substitution rate and the GC content: implications for the evolution of isochores.

18 March 2024

70

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Are rare variants responsible for susceptibility to complex diseases?

18 March 2024

71

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Confidence interval for the number of selectively neutral amino acid polymorphisms

18 March 2024

73

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Patterns in spontaneous mutation revealed by human-baboon sequence comparison

18 March 2024

74

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Allele age and a test for selection on rare alleles

18 March 2024

75

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Adaptive protein evolution in Drosophila

18 March 2024

76

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Prediction of deleterious human alleles

18 March 2024

77

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

A method for detecting positive selection at single amino acid sites

18 March 2024

78

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Reliabilities of parsimony-based and likelihood-based methods for detecting positive selection at single amino acid sites.

18 March 2024

79

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Simulation study of the reliability and robustness of the statistical methods for detecting positive selection at single amino acid sites

18 March 2024

80

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Statistical models of the overdispersed molecular clock

18 March 2024

81

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Divergence time and population size in the lineage leading to modern humans

18 March 2024

82

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The phylogeny of closely related species as revealed by the genealogy of a speciation gene, Odysseus

18 March 2024

85

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

A rapidly evolving homeobox at the site of a hybrid sterility gene

18 March 2024

86

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Positive selection and the molecular evolution of a gene of male reproduction, Acp26Aa of Drosophila.

18 March 2024

87

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Initial sequencing and comparative analysis of the mouse genome

18 March 2024

89

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Estimating the proportion of neutral mutants

18 March 2024

90

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

The Distribution of Gene Frequencies Under Irreversible Mutation

18 March 2024

92

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Evidence for higher rates of nucleotide substitution in rodents than in man

18 March 2024

93

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Genetics of postmating reproductive isolation in animals

18 March 2024

94

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Rapid evolution of male reproductive genes in the descent of man.

18 March 2024

95

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution

18 March 2024

97

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Statistical methods for detecting molecular adaptation

18 March 2024

98

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Synonymous and nonsynonymous rate variation in nuclear genes of mammals.

18 March 2024

99

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Estimating synonymous and nonsynonymous substitution rates under realistic evolutionary models

18 March 2024

100

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Codon-substitution models for detecting molecular adaptation at individual sites along specific lineages

18 March 2024

101

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

DNA polymorphism in a worldwide sample of human X chromosomes.

18 March 2024

103

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Positive Darwinian selection after gene duplication in primate ribonuclease genes

18 March 2024

104

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

Evolutionary Divergence and Convergence in Proteins

18 March 2024

105

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENOM.4.020303.162528

18 March 2024

Identifiers

1 reference

8 August 2017

1 reference