(Q35551193)

8 August 2017

title

Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice (English)

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8 August 2017

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Scharstuhl A

1

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8 August 2017

van Beuningen HM

2

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8 August 2017

Vitters EL

3

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8 August 2017

van der Kraan PM

4

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8 August 2017

van den Berg WB

5

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8 August 2017

language of work or name

English

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publication date

1 December 2002

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Annals of the Rheumatic Diseases

8 August 2017

published in

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8 August 2017

volume

61

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8 August 2017

issue

12

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8 August 2017

page(s)

1095-1098

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TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

8 August 2017

cites work

1 reference

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27 July 2018

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The role of the chondrocyte in osteoarthritis

27 July 2018

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The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models

27 July 2018

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Signaling inputs converge on nuclear effectors in TGF-beta signaling

27 July 2018

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Smad7 differentially regulates transforming growth factor beta-mediated signaling pathways

27 July 2018

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Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage

27 July 2018

1 reference

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The role of nitric oxide in articular cartilage breakdown in osteoarthritis.

27 July 2018

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Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

27 July 2018

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Aging and osteoarthritis: basic mechanisms

27 July 2018

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In vivo protection against interleukin-1-induced articular cartilage damage by transforming growth factor-beta 1: age-related differences

27 July 2018

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27 July 2018

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Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta

27 July 2018

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27 July 2018

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Transforming growth factor-beta is a potent inhibitor of IL-1 induced protease activity and cartilage proteoglycan degradation

27 July 2018

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Active and latent forms of transforming growth factor beta activity in synovial effusions

27 July 2018

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Transforming growth factor-beta in calf articular cartilage organ cultures: synthesis and distribution

27 July 2018

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Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes

27 July 2018

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Smad6 inhibits signalling by the TGF-beta superfamily

26 September 2018

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Protection from interleukin 1 induced destruction of articular cartilage by transforming growth factor beta: studies in anatomically intact cartilage in vitro and in vivo

26 September 2018

1 reference

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The regulation of MMPs and TIMPs in cartilage turnover

26 September 2018

1 reference

12 December 2020

Quantitation of glycosaminoglycan metabolism in anatomically intact articular cartilage of the mouse patella: in vitro and in vivo studies with 35S-sulfate, 3H-glucosamine, and 3H-acetate

1 reference

12 December 2020

Transforming growth factor-beta and cellular immune responses in synovial fluids

1 reference

12 December 2020

In vivo effects of interleukin-1 on articular cartilage. Prolongation of proteoglycan metabolic disturbances in old mice

1 reference

12 December 2020

Protection against cartilage proteoglycan synthesis inhibition by antiinterleukin 1 antibodies in experimental arthritis

1 reference

12 December 2020

Osteoarthritic human cartilage is more sensitive to transforming growth factor beta than is normal cartilage

1 reference

12 December 2020

Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint

1 reference

12 December 2020

Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced arthritis

1 reference

12 December 2020

Coordinate regulation of matrix metalloproteases and tissue inhibitor of metalloproteinase expression in human synovial fibroblasts

1 reference

12 December 2020

Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies

1 reference

12 December 2020

Transforming growth factor-beta predominantly stimulates phenotypically changed chondrocytes in osteoarthritic human cartilage

1 reference

12 December 2020

Effect of interleukin 1 and leukaemia inhibitory factor on chondrocyte metabolism in articular cartilage from normal and interleukin-6-deficient mice: role of nitric oxide and IL-6 in the suppression of proteoglycan synthesis

1 reference

12 December 2020

Reduced cartilage proteoglycan loss during zymosan-induced gonarthritis in NOS2-deficient mice and in anti-interleukin-1-treated wild-type mice with unabated joint inflammation

1 reference

12 December 2020

Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States

1 reference

12 December 2020

Expression of the tissue inhibitor of metalloproteinases (TIMP) gene family in normal and osteoarthritic joints

1 reference

12 December 2020

Identifiers

DOI

10.1136/ARD.61.12.1095

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8 August 2017

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8 August 2017

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