(Q35552523)

8 August 2017

1 reference

title

The proteasome: a novel therapeutic target in haematopoietic malignancy (English)

1 reference

8 August 2017

Laura Magill

1

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8 August 2017

Brian Walker

series ordinal

2

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8 August 2017

Alexandra E Irvine

series ordinal

3

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8 August 2017

publication date

1 October 2003

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8 August 2017

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8 August 2017

volume

8

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8 August 2017

issue

5

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8 August 2017

page(s)

275-283

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Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression

8 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Novel therapies targeting the myeloma cell and its bone marrow microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Proteolysis, proteasomes and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Antizyme, a mediator of ubiquitin-independent proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

The ubiquitin-proteasome proteolytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

A gated channel into the proteasome core particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Structure of 20S proteasome from yeast at 2.4 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Penicillin acylase has a single-amino-acid catalytic centre

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Evolution of proteasomal ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

The base of the proteasome regulatory particle exhibits chaperone-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

The proteasome, a novel protease regulated by multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Antigen presentation by MHC class I and its regulation by interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Degradation of cell proteins and the generation of MHC class I-presented peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Evidence that pituitary cation-sensitive neutral endopeptidase is a multicatalytic protease complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Abnormally high expression of proteasomes in human leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Nuclear transcription factor-kappaB as a target for cancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Activation of the cell death program by inhibition of proteasome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Molecular sequelae of proteasome inhibition in human multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Degradation of MyoD by the ubiquitin pathway: regulation by specific DNA-binding and identification of a novel site for ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

A new inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (20S proteasome) induces accumulation of ubiquitin-protein conjugates in a neuronal cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl alpha-keto aldehydes (glyoxals)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

QSR1, an essential yeast gene with a genetic relationship to a subunit of the mitochondrial cytochrome bc1 complex, codes for a 60 S ribosomal subunit protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10245330310001604755

10.1080/10245330310001604755

21 January 2018

Identifiers

DOI

1 reference

8 August 2017

1 reference