(Q35558172)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

review article

2 references

29 October 2020

Clinical review: gene-based therapies for ALI/ARDS: where are we now? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

acute respiratory distress syndrome

5 February 2020

main subject

3 references

25 June 2019

19 September 2019

29 October 2020

biomedical investigative technique

1 reference

19 September 2019

1 reference

29 October 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

John G Laffey

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Maya Contreras

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

publication date

20 June 2011

4 references

25 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

29 October 2020

4 references

25 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

29 October 2020

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

224

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/cc10216

5 February 2020

exact match

0 references

cites work

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12 July 2018

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Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis

12 July 2018

1 reference

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Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis

12 July 2018

1 reference

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Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial

12 July 2018

1 reference

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Effects of intratracheal administration of nuclear factor-kappaB decoy oligodeoxynucleotides on long-term cigarette smoke-induced lung inflammation and pathology in mice

12 July 2018

1 reference

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Silencing CD36 gene expression results in the inhibition of latent-TGF-beta1 activation and suppression of silica-induced lung fibrosis in the rat.

12 July 2018

1 reference

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Optimized aerosol delivery to a mechanically ventilated rodent

12 July 2018

1 reference

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Stabilized integrin-targeting ternary LPD (lipopolyplex) vectors for gene delivery designed to disassemble within the target cell

12 July 2018

1 reference

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Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy

12 July 2018

1 reference

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Tailoring the AAV vector capsid for gene therapy.

12 July 2018

1 reference

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Analysis of adeno-associated virus progenitor cell transduction in mouse lung.

12 July 2018

1 reference

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Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

12 July 2018

1 reference

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Stem cells and cell therapies in lung biology and lung diseases

12 July 2018

1 reference

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GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium

12 July 2018

1 reference

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Recent developments in adeno-associated virus vector technology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Artificial evolution with adeno-associated viral libraries

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.

12 July 2018

1 reference

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Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome

12 July 2018

1 reference

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Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1

12 July 2018

1 reference

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Development of lentiviral vectors with regulated respiratory epithelial expression in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Electroporation-mediated gene transfer of the Na+,K+ -ATPase rescues endotoxin-induced lung injury.

12 July 2018

1 reference

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Electroporation-mediated transfer of plasmids to the lung results in reduced TLR9 signaling and inflammation

12 July 2018

1 reference

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Interleukin-10 gene transfer: prevention of multiple organ injury in a murine cecal ligation and puncture model of sepsis.

12 July 2018

1 reference

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Calculating expected lung deposition of aerosolized administration of AAV vector in human clinical studies

12 July 2018

1 reference

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Protection against Pseudomonas aeruginosa pneumonia and sepsis-induced lung injury by overexpression of beta-defensin-2 in rats

12 July 2018

1 reference

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Adenoviral-mediated overexpression of SOCS3 enhances IgG immune complex-induced acute lung injury

12 July 2018

1 reference

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Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury.

12 July 2018

1 reference

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Spatial and temporal expression of surfactant proteins in hyperoxia-induced neonatal rat lung injury.

12 July 2018

1 reference

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Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis

12 July 2018

1 reference

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RNA interference for alpha-ENaC inhibits rat lung fluid absorption in vivo

12 July 2018

1 reference

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Incidence and outcomes of acute lung injury

12 July 2018

1 reference

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In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury

12 July 2018

1 reference

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Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

12 July 2018

1 reference

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Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha

12 July 2018

1 reference

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Epidemiology of acute lung injury

12 July 2018

1 reference

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Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Adenoviral augmentation of elafin protects the lung against acute injury mediated by activated neutrophils and bacterial infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Intrapulmonary TNF gene therapy reverses sepsis-induced suppression of lung antibacterial host defense

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

A human epithelium-specific vector optimized in rat pneumocytes for lung gene therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.

12 July 2018

1 reference

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The acute respiratory distress syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

One-year outcomes in survivors of the acute respiratory distress syndrome.

12 July 2018

1 reference

Aerosol Delivery of aβ-Galactosidase Adenoviral Vector to the Lungs of Rodents

21 January 2018

1 reference

Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions

21 January 2018

1 reference

Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial

21 January 2018

1 reference

Effect of antisense oligonucleotides to nuclear factor-kappaB on the survival of LPS-induced ARDS in mouse.

21 January 2018

1 reference

A receptor-targeted nanocomplex vector system optimized for respiratory gene transfer

21 January 2018

1 reference

Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial.

21 January 2018

1 reference

RNA interference therapy in lung transplant patients infected with respiratory syncytial virus

21 January 2018

1 reference

Prevention of lung ischemia-reperfusion injury by short hairpin RNA-mediated caspase-3 gene silencing

21 January 2018

1 reference

Nuclear factor-kappaB decoy oligodeoxynucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis

21 January 2018

1 reference

Cell-based angiopoietin-1 gene therapy for acute lung injury.

21 January 2018

1 reference

Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium

21 January 2018

1 reference

Adenoviral gene transfer of a mutant surfactant enzyme ameliorates pseudomonas-induced lung injury.

21 January 2018

1 reference

Gene therapy for oxidant injury-related diseases: adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury

21 January 2018

1 reference

Human ApoA-I overexpression diminishes LPS-induced systemic inflammation and multiple organ damage in mice

21 January 2018

1 reference

Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure

21 January 2018

1 reference

Pretreatment with cationic lipid-mediated transfer of the Na+K+-ATPase pump in a mouse model in vivo augments resolution of high permeability pulmonary oedema

21 January 2018

1 reference

Caveolin-1 siRNA Increases the Pulmonary Microvascular and Alveolar Epithelial Permeability in Rats

21 January 2018

1 reference

Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury.

21 January 2018

1 reference

Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension.

21 January 2018

1 reference

Microvascular regeneration in established pulmonary hypertension by angiogenic gene transfer.

21 January 2018

1 reference

Tetracycline-inducible transgene expression mediated by a single AAV vector.

21 January 2018

1 reference

Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.

21 January 2018

1 reference

Analysis and optimization of the cationic lipid component of a lipid/peptide vector formulation for enhanced transfection in vitro and in vivo.

21 January 2018

1 reference

Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice

21 January 2018

1 reference

Adenoviral vector transfection into the pulmonary epithelium after cecal ligation and puncture in rats.

21 January 2018

1 reference

PECAM-directed delivery of catalase to endothelium protects against pulmonary vascular oxidative stress

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Acute lung injury does not impair adenoviral-mediated gene transfer to the alveolar epithelium.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Targeting type II and Clara cells for adenovirus-mediated gene transfer using the surfactant protein B promoter

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218971

Repeated Aerosolized AAV-CFTR for Treatment of Cystic Fibrosis: A Randomized Placebo-Controlled Phase 2B Trial

26 September 2018

1 reference

Angiopoietin-1 increases survival and reduces the development of lung edema induced by endotoxin administration in a murine model of acute lung injury

21 January 2018

1 reference

12 December 2020

Overexpression of the Na-K-ATPase alpha2-subunit improves lung liquid clearance during ventilation-induced lung injury

1 reference

12 December 2020

A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis

1 reference

12 December 2020

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

1 reference

12 December 2020

Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector

1 reference

12 December 2020

Nonviral gene delivery with indoleamine 2,3-dioxygenase targeting pulmonary endothelium protects against ischemia-reperfusion injury

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC10216

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21699743%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

21699743

1 reference