(Q35560770)

English

Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

scientific article published on 23 May 2011

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scholarly article

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1 February 2020

Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma (English)

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1 February 2020

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Jean-Christophe Bourdon

8

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1 February 2020

13

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1 February 2020

author name string

S A Watt

1

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C Pourreyron

2

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K Purdie

3

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C Hogan

4

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C L Cole

5

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1 February 2020

N Foster

6

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N Pratt

7

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V Appleyard

9

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K Murray

10

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A M Thompson

11

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X Mao

12

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L Bruckner-Tuderman

14

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A Evans

15

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C M Proby

17

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J Foerster

18

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1 February 2020

I M Leigh

19

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1 February 2020

A P South

20

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23 May 2011

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4666-4677

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1 February 2020

describes a project that uses

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https://scigraph.springernature.com/pub.10.1038/onc.2011.180

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Polo-like kinase 1 (Plk1) as a novel drug target in chronic myeloid leukemia: overriding imatinib resistance with the Plk1 inhibitor BI 2536.

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Gene expression profiling in head and neck squamous cell carcinoma

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Targeting Polo-like kinase in cancer therapy

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12 July 2018

C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer

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Systematic comparison of nonmelanoma skin cancer microarray datasets reveals lack of consensus genes

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Polo-like kinase 1 (Plk1) in non-melanoma skin cancers

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12 July 2018

Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells

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The activated NF-kappaB-Snail-RKIP circuitry in cancer regulates both the metastatic cascade and resistance to apoptosis by cytotoxic drugs

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Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology

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Single nucleotide polymorphism array analysis defines a specific genetic fingerprint for well-differentiated cutaneous SCCs

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The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

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Regulation of mitosis via mitotic kinases: new opportunities for cancer management

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RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.

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Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis

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12 July 2018

Cutaneous head and neck squamous cell carcinoma metastatic to parotid and cervical lymph nodes

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12 July 2018

Cancer as an evolutionary and ecological process

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12 July 2018

Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling

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12 July 2018

Normal cells, but not cancer cells, survive severe Plk1 depletion

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12 July 2018

Non-melanoma skin cancer in Australia: the 2002 national survey and trends since 1985.

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Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

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12 July 2018

Overexpression of phosphorylated-STAT3 correlated with the invasion and metastasis of cutaneous squamous cell carcinoma

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12 July 2018

Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals

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Polo-like kinases (Plks) and cancer

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Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex

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TP53 mutations in human skin cancers.

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Systematic variation in gene expression patterns in human cancer cell lines

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The Hallmarks of Cancer

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Telangiectasia of the lower extremity

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31 March 2020

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31 March 2020

Metastases of sun-induced SCC

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12 December 2020

based on heuristic

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Clonal proliferation of cultured nonmalignant and malignant human breast epithelia

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/ONC.2011.180

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Europe PubMed Central

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1 February 2020

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Europe PubMed Central

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1 February 2020

1 reference

Europe PubMed Central

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1 February 2020

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