(Q35568019)

8 August 2017

1 reference

title

Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection (English)

1 reference

8 August 2017

1 reference

1 reference

David Milich

1

1 reference

8 August 2017

T. Jake Liang

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14578844

25 March 2024

language of work or name

English

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publication date

1 November 2003

1 reference

full work available at URL

8 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1053%2Fjhep.2003.50453

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

https://onlinelibrary.wiley.com/doi/full/10.1053/jhep.2003.50453

25 March 2024

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

25 March 2024

1 reference

8 August 2017

38

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8 August 2017

1075-1086

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8 August 2017

5

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The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host

8 August 2017

4

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Antigenic determinants and functional domains in core antigen and e antigen from hepatitis B virus

25 March 2024

5

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B virus capsid: localization of the putative immunodominant loop (residues 78 to 83) on the capsid surface, and implications for the distinction between c and e-antigens.

25 March 2024

6

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Three-dimensional structure of hepatitis B virus core particles determined by electron cryomicroscopy

25 March 2024

7

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero?

25 March 2024

10

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B virus mutants with precore-region defects in two babies with fulminant hepatitis and their mothers positive for antibody to hepatitis B e antigen

25 March 2024

11

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Precore mutants revisited

25 March 2024

12

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Frequent and rapid emergence of mutated pre-C sequences in HBV from e-antigen positive carriers who seroconvert to anti-HBe during interferon treatment

25 March 2024

13

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B virus genotype A rarely circulates as an HBe-minus mutant: possible contribution of a single nucleotide in the precore region.

25 March 2024

14

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B viruses with precore region defects prevail in persistently infected hosts along with seroconversion to the antibody against e antigen

25 March 2024

16

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Defects in the precore region of the HBV genome in patients with chronic hepatitis B after sustained seroconversion from HBeAg to anti-HBe induced spontaneously or with interferon therapy

25 March 2024

17

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Chronic hepatitis in HBsAg carriers with serum HBV-DNA and anti-HBe

25 March 2024

19

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members

25 March 2024

21

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Precore stop mutant in HBeAg-positive patients with chronic hepatitis B: clinical characteristics and correlation with the course of HBeAg-to-anti-HBe seroconversion

25 March 2024

22

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Precore wild-type DNA and immune complexes persist in chronic hepatitis B after seroconversion: no association between genome conversion and seroconversion

25 March 2024

24

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis.

25 March 2024

25

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis

25 March 2024

27

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Is the course of perinatal hepatitis B virus infection influenced by genetic heterogeneity of the virus?

25 March 2024

28

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Transmission of a homogenous hepatitis B virus population of A1896-containing strains leading to mild resolving acute hepatitis and seroconversion to hepatitis B e antigen antibodies in an adult

25 March 2024

29

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Fulminant hepatitis B in successive female sexual partners of two anti-HBe-positive males.

25 March 2024

30

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis

25 March 2024

31

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Molecular epidemiology of an outbreak of fulminant hepatitis B.

25 March 2024

32

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Three cases of severe subfulminant hepatitis in heart-transplanted patients after nosocomial transmission of a mutant hepatitis B virus

25 March 2024

33

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

A common-source outbreak of fulminant hepatitis B in hemodialysis patients induced by precore mutant

25 March 2024

34

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Selection of a precore mutant after vertical transmission of different hepatitis B virus variants is correlated with fulminant hepatitis in infants

25 March 2024

35

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Variations of hepatitis B virus precore/core gene sequence in acute and fulminant hepatitis B.

25 March 2024

36

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Mutations in the basic core promotor and the precore region of hepatitis B virus and their selection in children with fulminant and chronic hepatitis B.

25 March 2024

37

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Nucleotide sequence analysis of the precore region in patients with fulminant hepatitis B in the United States

25 March 2024

38

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B virus precore mutation and fulminant hepatitis in the United States. A polymerase chain reaction-based assay for the detection of specific mutation

25 March 2024

39

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B virus genomes of patients with fulminant hepatitis do not share a specific mutation

25 March 2024

40

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Type, prevalence, and significance of core promoter/enhancer II mutations in hepatitis B viruses from immunosuppressed patients with severe liver disease.

25 March 2024

41

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B.

25 March 2024

42

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis

25 March 2024

44

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication

25 March 2024

45

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication

25 March 2024

46

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Reduced precore transcription and enhanced core-pregenome transcription of hepatitis B virus DNA after replacement of the precore-core promoter with sequences associated with e antigen-seronegative persistent infections.

25 March 2024

47

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

A hepatitis B virus mutant with a new hepatocyte nuclear factor 1 binding site emerging in transplant-transmitted fulminant hepatitis B.

25 March 2024

48

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Functional analysis of HBV genomes from patients with fulminant hepatitis

25 March 2024

49

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Enhanced replication contributes to enrichment of hepatitis B virus with a deletion in the core gene

25 March 2024

50

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis

25 March 2024

51

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Precore-mediated inhibition of hepatitis B virus progeny DNA synthesis.

25 March 2024

52

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

The hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice

25 March 2024

53

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Mechanism, kinetics, and role of duck hepatitis B virus e-antigen expression in vivo

25 March 2024

54

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Coinfection study of precore mutant and wild-type hepatitis B-like virus in ducklings

25 March 2024

55

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Decrease of wild-type and precore mutant duck hepatitis B virus replication during lamivudine treatment in white Pekin ducks infected with the viruses

25 March 2024

56

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Enrichment of a precore-minus mutant of duck hepatitis B virus in experimental mixed infections

25 March 2024

57

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection

25 March 2024

59

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees

25 March 2024

60

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

The nucleocapsid of hepatitis B virus is both a T-cell-independent and a T-cell-dependent antigen

25 March 2024

61

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen

25 March 2024

62

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Characterization of CD8+ cytotoxic T-lymphocyte responses after genetic immunization with retrovirus vectors expressing different forms of the hepatitis B virus core and e antigens.

25 March 2024

63

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection

25 March 2024

66

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Interleukin 12 suppresses autoantibody production by reversing helper T-cell phenotype in hepatitis B e antigen transgenic mice

25 March 2024

70

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Role of B cells in antigen presentation of the hepatitis B core

25 March 2024

71

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

The hepatitis B virus e antigen cannot pass the murine placenta efficiently and does not induce CTL immune tolerance in H-2b mice in utero

25 March 2024

72

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Maternofetal transmission of IgG-bound hepatitis B e antigen

25 March 2024

75

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Prevention of maternal-infant hepatitis B virus transmission by immunization: the role of serum hepatitis B virus DNA.

25 March 2024

76

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Cellular immune response to HBcAg in mother-to-infant transmission of hepatitis B virus

25 March 2024

77

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Infection of the fetus with hepatitis B e antigen via the placenta

25 March 2024

78

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

The serology of chronic hepatitis B infection revisited

25 March 2024

79

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection

25 March 2024

82

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

25 March 2024

83

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Emergence of the precore mutant late in chronic hepatitis B infection correlates with the severity of liver injury and mutations in the core region

25 March 2024

85

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Mutations in core nucleotide sequence of hepatitis B virus correlate with fulminant and severe hepatitis

25 March 2024

86

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection

25 March 2024

87

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Characterization of self-reactive T cells that evade tolerance in hepatitis B e antigen transgenic mice

25 March 2024

88

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Nondeletional T-cell receptor transgenic mice: model for the CD4(+) T-cell repertoire in chronic hepatitis B virus infection

25 March 2024

89

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Acute exacerbations of chronic type B hepatitis are accompanied by increased T cell responses to hepatitis B core and e antigens. Implications for hepatitis B e antigen seroconversion

25 March 2024

90

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Differential antigen-processing pathways of the hepatitis B virus e and core proteins

25 March 2024

91

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Absence of hepatitis B virus precore mutants in patients with chronic hepatitis B responding to interferon-alpha

25 March 2024

92

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Response to Interferon-α2a in Patients with e Antigen-Negative Chronic Hepatitis B

25 March 2024

93

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

A randomized controlled trial of lymphoblastoid interferon-alpha in patients with chronic hepatitis B lacking HBeAg

25 March 2024

94

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Anti-HBe-positive chronic hepatitis B with HBV-DNA in the serum response to a 6-month course of lymphoblastoid interferon.

25 March 2024

95

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum

25 March 2024

96

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Interferon therapy for the anti-HBe positive form of chronic hepatitis B.

25 March 2024

97

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study

25 March 2024

98

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Interferon alpha treatment and retreatment of hepatitis B e antigen-negative chronic hepatitis B.

25 March 2024

99

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Long-term evaluation of recombinant interferon alpha2b in the treatment of patients with hepatitis B e antigen-negative chronic hepatitis B in Taiwan

25 March 2024

100

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Efficacy of lamivudine in patients with hepatitis B e antigen-negative/hepatitis B virus DNA-positive (precore mutant) chronic hepatitis B. Lamivudine Precore Mutant Study Group

25 March 2024

101

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Long-term therapy of chronic hepatitis B with lamivudine.

25 March 2024

102

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease

25 March 2024

103

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Effect of the G1896A precore mutation on drug sensitivity and replication yield of lamivudine-resistant HBV in vitro

25 March 2024

104

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B.

25 March 2024

105

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50453

25 March 2024

Identifiers

1 reference

8 August 2017

1 reference