(Q35572437)

8 August 2017

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title

COX-2 inhibitors for the prevention of breast cancer (English)

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8 August 2017

Louise R Howe

1

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8 August 2017

Andrew J Dannenberg

series ordinal

2

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8 August 2017

publication date

1 January 2003

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Journal of Mammary Gland Biology and Neoplasia

8 August 2017

published in

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8 August 2017

volume

8

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8 August 2017

issue

1

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8 August 2017

page(s)

31-43

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In vivo effects of indomethacin on the growth of murine mammary tumors

8 August 2017

cites work

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12 December 2020

Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

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12 December 2020

Photodynamic therapy for chest wall progression from breast carcinoma is an underutilized treatment modality

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12 December 2020

Ibuprofen-induced inhibition of cyclooxygenase isoform gene expression and regression of rat mammary carcinomas

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12 December 2020

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

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12 December 2020

PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2.

1 reference

12 December 2020

Inhibitory effects of diallyl disulfide or aspirin on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary carcinogenesis in rats.

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12 December 2020

Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis

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12 December 2020

Role of arachidonic acid metabolism in the mitogenic response of BALB/c 3T3 fibroblasts to epidermal growth factor

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12 December 2020

Cyclooxygenase-2 (COX-2) enzyme inhibitors as potential enhancers of tumor radioresponse

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12 December 2020

Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene

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12 December 2020

Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.

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12 December 2020

Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth

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12 December 2020

Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression

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12 December 2020

Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines.

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12 December 2020

NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

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12 December 2020

Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP(1) antagonist, on breast cancer development

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12 December 2020

Aspirin use and chronic diseases: a cohort study of the elderly

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12 December 2020

Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture

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12 December 2020

Expression of cyclooxygenase-1 and -2 in human colorectal cancer

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12 December 2020

Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ.

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12 December 2020

Cyclooxygenase-2: a target for the prevention and treatment of breast cancer

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12 December 2020

Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

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12 December 2020

Involvement of cyclo-oxygenase-2 in osteoclast formation and bone destruction in bone metastasis of mammary carcinoma cell lines

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12 December 2020

Nonsteroidal anti-inflammatory drug use and protection against colorectal cancer in women

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12 December 2020

Effect of the prostaglandin synthetase inhibitor indomethacin on 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats fed different levels of fat

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12 December 2020

Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice

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12 December 2020

The effect of selective cyclooxygenase-2 inhibitor on corneal angiogenesis in the rat.

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12 December 2020

Host cyclooxygenase-2 modulates carcinoma growth.

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12 December 2020

Dietary fat and colon cancer: modulation of cyclooxygenase-2 by types and amount of dietary fat during the postinitiation stage of colon carcinogenesis.

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12 December 2020

Non-small cell lung cancer-derived soluble mediators and prostaglandin E2 enhance peripheral blood lymphocyte IL-10 transcription and protein production

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12 December 2020

Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction.

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12 December 2020

The mRNA expression of cyclo-oxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) in human breast cancer.

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12 December 2020

Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing

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12 December 2020

Correlation of aromatase and cyclooxygenase gene expression in human breast cancer specimens

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12 December 2020

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis

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12 December 2020

Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat

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12 December 2020

Carcinogen substrate specificity of human COX-1 and COX-2.

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12 December 2020

Prostanoid receptors: structures, properties, and functions

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12 December 2020

Nimesulide and melatonin in mammary carcinogenesis prevention in female Sprague-Dawley rats.

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12 December 2020

Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo

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12 December 2020

Cyclooxygenase-2 inhibitor celecoxib inhibits promotion of mammary tumorigenesis in rats fed a high fat diet rich in n-6 polyunsaturated fatty acids

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12 December 2020

Recent considerations in nonsteroidal anti-inflammatory drug gastropathy

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12 December 2020

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

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12 December 2020

Early cell cycle diacylglycerol (DAG) content and protein kinase C (PKC) activity enhancement potentiates prostaglandin F2 alpha (PGF2 alpha) induced mitogenesis in Swiss 3T3 cells

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12 December 2020

Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells.

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12 December 2020

Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis.

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12 December 2020

Elevated cyclooxygenase-2 levels in Min mouse adenomas

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12 December 2020

Prostaglandins and breast cancer

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12 December 2020

The association between a mutated ras gene and cyclooxygenase-2 expression in human breast cancer cell lines

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12 December 2020

Prostanoids play a major role in the primary tumor-induced inhibition of dendritic cell differentiation

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12 December 2020

Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer

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12 December 2020

Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis

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12 December 2020

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

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12 December 2020

Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo

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12 December 2020

Intracellular unesterified arachidonic acid signals apoptosis

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12 December 2020

Aspirin use and lung, colon, and breast cancer incidence in a prospective study

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12 December 2020

Reduced risk of large-bowel adenomas among aspirin users. The Polyp Prevention Study Group

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12 December 2020

Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer

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12 December 2020

Modulation of rat mammary carcinogenesis by indomethacin.

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12 December 2020

Linoleate metabolites enhance the in vitro proliferative response of mouse mammary epithelial cells to epidermal growth factor

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12 December 2020

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

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12 December 2020

Comparative effects of piroxicam and esculetin on incidence, proliferation, and cell kinetics of mammary carcinomas induced by 7,12-dimethylbenz[a]anthracene in rats on high- and low-fat diets.

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12 December 2020

Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer.

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12 December 2020

Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect

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12 December 2020

Cyclooxygenase-2 inhibitor treatment enhances photodynamic therapy-mediated tumor response.

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12 December 2020

Adverse upper gastrointestinal effects of rofecoxib compared with NSAIDs

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12 December 2020

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

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12 December 2020

Prostaglandin synthase 2.

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12 December 2020

Prospective study of regular aspirin use and the risk of breast cancer

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12 December 2020

G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2.

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12 December 2020

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

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12 December 2020

Prostaglandin in human breast cancer: Evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells.

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12 December 2020

Aspirin use, cancer, and polyps of the large bowel

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12 December 2020

Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines

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12 December 2020

Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme

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12 December 2020

Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps

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12 December 2020

Inhibition of mammary carcinogenesis by flurbiprofen, a non-steroidal antiinflammatory agent

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12 December 2020

Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis.

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12 December 2020

Aspirin and the potential role of prostaglandins in colon cancer

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12 December 2020

Chemoprevention of breast cancer in rats by celecoxib, a cyclooxygenase 2 inhibitor

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12 December 2020

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

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12 December 2020

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

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12 December 2020

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

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12 December 2020

Chemotherapeutic evaluation of Celecoxib, a cyclooxygenase-2 inhibitor, in a rat mammary tumor model

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12 December 2020

Effects of the prostaglandin synthetase inhibitor indomethacin on tumorigenesis, tumor proliferation, cell kinetics, and receptor contents of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in Sprague-Dawley rats fed a high- or low-fat diet

1 reference

12 December 2020

Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2.

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12 December 2020

Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial

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12 December 2020

Prostaglandin F2 alpha-induced mitogenesis in MC3T3-E1 osteoblasts: role of protein kinase-C-mediated tyrosine phosphorylation

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12 December 2020

Photodynamic therapy: a review

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12 December 2020

Nonsteroidal antiinflammatory drugs and breast cancer

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12 December 2020

COX-2 is expressed in human pulmonary, colonic, and mammary tumors.

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12 December 2020

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

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12 December 2020

Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2

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12 December 2020

Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer

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12 December 2020

Inhibition by dietary menhaden oil of cyclooxygenase-1 and -2 in N-nitrosomethylurea-induced rat mammary tumors.

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12 December 2020

Chemoprevention by nimesulide, a selective cyclooxygenase-2 inhibitor, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary gland carcinogenesis in rats.

1 reference

12 December 2020

Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer

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12 December 2020

Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer.

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12 December 2020

Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

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12 December 2020

Modulation of the expression of the cyclooxygenase 1 and 2 genes in rat mammary glands: role of hormonal status and dietary fat

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12 December 2020

Aromatase and COX-2 expression in human breast cancers

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12 December 2020

Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis

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12 December 2020

Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells

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12 December 2020

Effects of D,L-2-difluoromethylornithine and indomethacin on mammary tumor promotion in rats fed high n-3 and/or n-6 fat diets

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12 December 2020

Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer.

1 reference

12 December 2020

Inhibition of tumor necrosis factor alpha-stimulated aromatase activity by microtubule-stabilizing agents, paclitaxel and 2-methoxyestradiol

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12 December 2020

Nested case-control study of the effects of non-steroidal anti-inflammatory drugs on breast cancer risk and stage

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12 December 2020

Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors

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12 December 2020

Significant roles of inducible cyclooxygenase (COX)-2 in angiogenesis in rat sponge implants

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12 December 2020

A comparison of the effects of the prostaglandin synthesis inhibitors indomethacin and carprofen on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats fed different amounts of essential fatty acid.

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12 December 2020

Aspirin use and reduced risk of fatal colon cancer

1 reference

12 December 2020

Chemoprevention of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine-induced mammary carcinogenesis in rats

1 reference

12 December 2020

Genetic induction and upregulation of cyclooxygenase (COX) and aromatase (CYP19): an extension of the dietary fat hypothesis of breast cancer

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12 December 2020

Studies of prostaglandins in rat mammary tumors induced by 7,12-dimethylbenz(a)anthracene.

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12 December 2020

Initial screening for carcinogenicity of commonly used drugs

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12 December 2020

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

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12 December 2020

Cyclooxygenase-2 gene expression in human breast cancer.

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12 December 2020

Identifiers

DOI

10.1023/A:1025731204719

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Dimensions Publication ID

8 August 2017

1031971707

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