(Q35575711)

8 August 2017

title

Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation (English)

1 reference

8 August 2017

Jeffrey K Davies

1

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8 August 2017

Lee M Nadler

series ordinal

2

1 reference

8 August 2017

Eva C Guinan

series ordinal

3

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8 August 2017

language of work or name

English

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publication date

1 October 2009

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Science Translational Medicine

8 August 2017

published in

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8 August 2017

volume

1

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8 August 2017

issue

1

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8 August 2017

page(s)

1ra3

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Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity

8 August 2017

cites work

1 reference

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CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages.

27 July 2018

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A clinical-scale selective allodepletion approach for the treatment of HLA-mismatched and matched donor-recipient pairs using expanded T lymphocytes as antigen-presenting cells and a TH9402-based photodepletion technique

27 July 2018

1 reference

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High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT

27 July 2018

1 reference

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Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease

27 July 2018

1 reference

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De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood

27 July 2018

1 reference

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The National Marrow Donor Program. Meeting the needs of the medically underserved

27 July 2018

1 reference

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

27 July 2018

1 reference

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Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

27 July 2018

1 reference

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The B7 and CD28 receptor families

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Graft-versus-leukemia reactions after bone marrow transplantation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Specific elimination of alloreactive T cells by an anti-interleukin-2 receptor B chain-specific immunotoxin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program

27 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Antiviral immunity and T-regulatory cell function are retained after selective alloreactive T-cell depletion in both the HLA-identical and HLA-mismatched settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Human peripheral blood T regulatory cells (Tregs), functionally primed CCR4+ Tregs and unprimed CCR4- Tregs, regulate effector T cells using FasL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Haploidentical stem cell transplantation: the always present but overlooked donor

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Assessment of optimal size and composition of the U.S. National Registry of hematopoietic stem cell donors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Racial and ethnic composition of volunteer cord blood donors: comparison with volunteer unrelated marrow donors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Human alloantigen-specific anergic cells induced by a combination of CTLA4-Ig and CsA maintain anti-leukemia and anti-viral cytotoxic responses

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Transplantation of anergic histoincompatible bone marrow allografts

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3225049

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

26 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000153

Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell

21 January 2018

1 reference

12 December 2020

MISMATCHED FAMILY DONORS FOR BONE-MARROW TRANSPLANTATION AS TREATMENT FOR ACUTE LEUKAEMIA

1 reference

12 December 2020

T cell depletion of HLA and haploidentical marrow reduces graft-versus-host disease but it may impair a graft-versus-leukemia effect

1 reference

12 December 2020

Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

1 reference

12 December 2020

Detection of intracellular cytokines by flow cytometry

1 reference

12 December 2020

Treatment of leukemia with partially matched related bone marrow transplantation

1 reference

12 December 2020

Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings

1 reference

12 December 2020

Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype

1 reference

12 December 2020

Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD

1 reference

12 December 2020

Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness

1 reference

12 December 2020

The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality

1 reference

12 December 2020

Human regulatory T cells control xenogeneic graft-versus-host disease induced by autologous T cells in RAG2-/-gammac-/- immunodeficient mice

1 reference

12 December 2020

10.1126/SCITRANSLMED.3000153

Identifiers

DOI

1 reference

8 August 2017

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8 August 2017

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