(Q35578981)

English

Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment.

scientific article published on 28 April 2015

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scholarly article

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6 March 2020

Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment (English)

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6 March 2020

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GOA release 2020-03-11

positive regulation of epithelial to mesenchymal transition

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GOA release 2020-03-11

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based on heuristic

inferred from title

18

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6 March 2020

author name string

Pu Li

1

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6 March 2020

Jing-Xuan Shan

2

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6 March 2020

Xue-Hua Chen

3

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6 March 2020

Di Zhang

4

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6 March 2020

Li-Ping Su

5

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6 March 2020

Xiu-Ying Huang

6

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6 March 2020

Bei-Qin Yu

7

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6 March 2020

Qiao-Ming Zhi

8

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6 March 2020

Cheng-Long Li

9

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6 March 2020

Ya-Qing Wang

10

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6 March 2020

Sara Tomei

11

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6 March 2020

Qu Cai

12

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6 March 2020

Jun Ji

13

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6 March 2020

Jian-Fang Li

14

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6 March 2020

Lotfi Chouchane

15

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6 March 2020

Ying-Yan Yu

16

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6 March 2020

Fang-Zhen Sun

17

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6 March 2020

Bing-Ya Liu

19

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6 March 2020

Zheng-Gang Zhu

20

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6 March 2020

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publication date

28 April 2015

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6 March 2020

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6 March 2020

25

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6 March 2020

5

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6 March 2020

588-603

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6 March 2020

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

28 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1038/cr.2015.51

0 references

Epigenetic alteration and microRNA dysregulation in cancer

1 reference

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12 July 2018

Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour-stroma interaction

1 reference

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12 July 2018

Retinoic acid inhibits pancreatic cancer cell migration and EMT through the downregulation of IL-6 in cancer associated fibroblast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423088

12 July 2018

MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer

1 reference

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12 July 2018

Epigenetic silencing of miR-338-3p contributes to tumorigenicity in gastric cancer by targeting SSX2IP.

1 reference

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12 July 2018

MiR-21/Smad 7 signaling determines TGF-β1-induced CAF formation

1 reference

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12 July 2018

The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis

1 reference

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12 July 2018

Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis

1 reference

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12 July 2018

Aldehyde dehydrogenase high gastric cancer stem cells are resistant to chemotherapy

1 reference

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12 July 2018

Hepatocyte growth factor activates tumor stromal fibroblasts to promote tumorigenesis in gastric cancer

1 reference

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12 July 2018

miRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423088

12 July 2018

MicroRNA-149 inhibits proliferation and invasion of glioma cells via blockade of AKT1 signaling

1 reference

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12 July 2018

MicroRNA: A Bridge from H. pylori Infection to Gastritis and Gastric Cancer Development

1 reference

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12 July 2018

MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer

1 reference

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12 July 2018

Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling

1 reference

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12 July 2018

Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK.

1 reference

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12 July 2018

Tumor microenvironment complexity: emerging roles in cancer therapy.

1 reference

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12 July 2018

Prostaglandin E2 promotes intestinal tumor growth via DNA methylation

1 reference

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12 July 2018

An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma

1 reference

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12 July 2018

Cancer associated fibroblasts: the dark side of the coin.

1 reference

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12 July 2018

MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423088

12 July 2018

DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423088

12 July 2018

Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423088

12 July 2018

Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423088

12 July 2018

PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423088

12 July 2018

IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis

1 reference

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12 July 2018

Histone H3K27ac separates active from poised enhancers and predicts developmental state

1 reference

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12 July 2018

The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.

1 reference

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12 July 2018

Specific protein and miRNA patterns characterise tumour-associated fibroblasts in bladder cancer

1 reference

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12 July 2018

Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma

1 reference

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12 July 2018

Eicosanoids and cancer

1 reference

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12 July 2018

Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression

1 reference

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12 July 2018

Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma

1 reference

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12 July 2018

Cancer associated fibroblasts in cancer pathogenesis

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12 July 2018

Differential influence of normal and cancer-associated fibroblasts on the growth of human epithelial cells in an in vitro cocultivation model of prostate cancer

1 reference

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12 July 2018

The basics of epithelial-mesenchymal transition

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12 July 2018

Tumor initiating potential of side population cells in human gastric cancer.

1 reference

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12 July 2018

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

1 reference

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12 July 2018

DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect

1 reference

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12 July 2018

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

1 reference

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12 July 2018

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

1 reference

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12 July 2018

The pathogenesis of Helicobacter pylori-induced gastro-duodenal diseases

1 reference

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12 July 2018

MicroRNA signatures in human cancers

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12 July 2018

Interactive effect of interleukin-6 and prostaglandin E2 on osteoclastogenesis via the OPG/RANKL/RANK system

1 reference

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12 July 2018

HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism

1 reference

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12 July 2018

Fibroblasts in cancer

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12 July 2018

Distinct epigenetic changes in the stromal cells of breast cancers

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12 July 2018

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

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12 July 2018

Fast and effective prediction of microRNA/target duplexes

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12 July 2018

Molecular characterization of the tumor microenvironment in breast cancer

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12 July 2018

Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells.

1 reference

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12 July 2018

Host cyclooxygenase-2 modulates carcinoma growth.

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12 July 2018

Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells.

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12 July 2018

Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: possible role of cyclooxygenase-2.

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12 July 2018

Interleukin-1β induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis

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26 September 2018

MiRNA expression analysis of cancer-associated fibroblasts and normal fibroblasts in breast cancer.

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26 September 2018

SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer

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26 September 2018

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

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26 September 2018

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

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26 September 2018

The tumour microenvironment as a target for chemoprevention.

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26 September 2018

High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk.

1 reference

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26 September 2018

Helicobacter pylori promotes development of pepsinogen-altered pyloric glands, a preneoplastic lesion of glandular stomach of BALB/c mice pretreated with N-methyl-N-nitrosourea

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26 September 2018

Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/25916550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 expression in gastric antral mucosa before and after eradication of Helicobacter pylori infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/25916550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25916550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CR.2015.51

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25916550%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

Europe PubMed Central

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6 March 2020

1 reference

Europe PubMed Central

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6 March 2020

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