(Q35585464)

9 August 2017

title

MicroRNA-16 modulates HuR regulation of cyclin E1 in breast cancer cells (English)

1 reference

9 August 2017

1 reference

Xun Guo

1

1 reference

9 August 2017

Melanie C Connick

2

1 reference

9 August 2017

Jennifer Vanderhoof

3

1 reference

9 August 2017

Mohammad-Ali Ishak

4

1 reference

9 August 2017

Rebecca S Hartley

5

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9 August 2017

language of work or name

English

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publication date

30 March 2015

1 reference

International Journal of Molecular Sciences

9 August 2017

published in

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9 August 2017

volume

16

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9 August 2017

issue

4

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9 August 2017

page(s)

7112-7132

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Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

30 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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12 July 2018

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The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2.

12 July 2018

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The RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cells

12 July 2018

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Competitive regulation of nucleolin expression by HuR and miR-494

12 July 2018

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Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability

12 July 2018

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HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis

12 July 2018

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siRNA-based targeting of cyclin E overexpression inhibits breast cancer cell growth and suppresses tumor development in breast cancer mouse model

12 July 2018

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HuR, a key post-transcriptional regulator, and its implication in progression of breast cancer

12 July 2018

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Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma

12 July 2018

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HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay

12 July 2018

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Down-regulation of the cyclin E1 oncogene expression by microRNA-16-1 induces cell cycle arrest in human cancer cells.

12 July 2018

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MicroRNA-125a represses cell growth by targeting HuR in breast cancer

12 July 2018

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HuR recruits let-7/RISC to repress c-Myc expression

12 July 2018

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miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes.

12 July 2018

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HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cells

12 July 2018

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12 July 2018

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MicroRNA gene expression deregulation in human breast cancer

12 July 2018

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Cyclin E as a prognostic and predictive marker in breast cancer

12 July 2018

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Cyclin E in normal and neoplastic cell cycles

12 July 2018

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Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Cyclin E ablation in the mouse

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

The oncogenic activity of cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

12 July 2018

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Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Novel splice variants of cyclin E with altered substrate specificity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Deregulated cyclin E induces chromosome instability

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Redundant cyclin overexpression and gene amplification in breast cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Cyclin E1 is a strong prognostic marker for death from lymph node negative breast cancer. A population-based case-control study.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Predictive and prognostic significance of cytoplasmic expression of ELAV-like protein HuR in invasive breast cancer treated with neoadjuvant chemotherapy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Cytoplasmic HuR expression correlates with P-gp, HER-2 positivity, and poor outcome in breast cancer.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Analysis of breast cancer related gene expression using natural splines and the Cox proportional hazard model to identify prognostic associations.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Prognostic role of HuR in hereditary breast cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Impact of cyclins E, neutrophil elastase and proteinase 3 expression levels on clinical outcome in primary breast cancer patients.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Cyclin E as molecular marker in the management of breast cancer: a review.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425007

Which cyclin E prevails as prognostic marker for breast cancer? Results from a retrospective study involving 635 lymph node-negative breast cancer patients

26 September 2018

1 reference

12 December 2020

Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma

1 reference

12 December 2020

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

12 December 2020

Kinase-independent function of cyclin E

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS16047112

1 reference

9 August 2017

1 reference

9 August 2017

1 reference