(Q35586230)

9 August 2017

1 reference

title

Molecular mechanisms and pharmacokinetics of phosphodiesterase-5 antagonists (English)

1 reference

9 August 2017

1 reference

1 reference

https://api.crossref.org/works/10.1007/S11934-003-0027-X

2 April 2024

author name string

Sharron H. Francis

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622499

2 April 2024

Jackie D. Corbin

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622499

2 April 2024

language of work or name

1 reference

1 December 2003

1 reference

full work available at URL

9 August 2017

https://link.springer.com/content/pdf/10.1007/s11934-003-0027-x.pdf

file format

Portable Document Format

1 reference

Crossref

https://api.crossref.org/works/10.1007/S11934-003-0027-X

https://link.springer.com/article/10.1007/s11934-003-0027-x/fulltext.html

2 April 2024

1 reference

https://api.crossref.org/works/10.1007/S11934-003-0027-X

http://link.springer.com/content/pdf/10.1007/s11934-003-0027-x

2 April 2024

1 reference

Crossref

https://api.crossref.org/works/10.1007/S11934-003-0027-X

2 April 2024

published in

Current urology reports

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9 August 2017

4

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9 August 2017

6

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9 August 2017

457-465

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https://scigraph.springernature.com/pub.10.1007/s11934-003-0027-x

9 August 2017

0 references

cites work

Allosteric sites of phosphodiesterase-5 (PDE5). A potential role in negative feedback regulation of cGMP signaling in corpus cavernosum

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12 December 2020

Cyclic GMP phosphodiesterase-5: target of sildenafil

1 reference

12 December 2020

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

12 December 2020

Signaling through NO and cGMP‐dependent protein kinases

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12 December 2020

Cyclic nucleotide phosphodiesterases: relating structure and function

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12 December 2020

Effects of sildenafil on esophageal motility of patients with idiopathic achalasia

1 reference

12 December 2020

Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises

1 reference

12 December 2020

Activation of purified guanylate cyclase by nitric oxide requires heme. Comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung

1 reference

12 December 2020

Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro

1 reference

12 December 2020

Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro

1 reference

12 December 2020

Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds

1 reference

12 December 2020

Hemodynamic effects of sildenafil in men with severe coronary artery disease

1 reference

12 December 2020

Expression of three isoforms of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in human penile cavernosum

1 reference

12 December 2020

Sustained efficacy and tolerability of vardenafil, a highly potent selective phosphodiesterase type 5 inhibitor, in men with erectile dysfunction: results of a randomized, double-blind, 26-week placebo-controlled pivotal trial

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12 December 2020

Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling

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12 December 2020

Cyclic nucleotide phosphodiesterases: gene complexity, regulation by phosphorylation, and physiological implications

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12 December 2020

The structure of a bovine lung cGMP-binding, cGMP-specific phosphodiesterase deduced from a cDNA clone.

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12 December 2020

Effects of sildenafil citrate (viagra) on blood pressure in normotensive and hypertensive men.

1 reference

12 December 2020

The efficacy and tolerability of vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction: the first at-home clinical trial

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12 December 2020

Pharmacology of phosphodiesterase-5 inhibitors.

1 reference

12 December 2020

Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission

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12 December 2020

Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

1 reference

12 December 2020

Sildenafil citrate does not affect cardiac contractility in human or dog heart

1 reference

12 December 2020

Vardenafil for treatment of men with erectile dysfunction: efficacy and safety in a randomized, double-blind, placebo-controlled trial.

1 reference

12 December 2020

Phosphodiesterase 5 inhibitors: current status and potential applications

1 reference

12 December 2020

Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase

1 reference

12 December 2020

Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression.

1 reference

12 December 2020

Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action

1 reference

12 December 2020

Use of sildenafil citrate in Raynaud's phenomenon: comment on the article by Thompson et al.

1 reference

12 December 2020

Modulation of human platelet aggregation by the phosphodiesterase type 5 inhibitor sildenafil

1 reference

12 December 2020

[3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP.

1 reference

12 December 2020

Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats

1 reference

12 December 2020

Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle.

1 reference

12 December 2020

Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients: a RigiScan and pharmacokinetic study

1 reference

12 December 2020

Three-year update of sildenafil citrate (Viagra) efficacy and safety

1 reference

12 December 2020

Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities

1 reference

12 December 2020

A 4-year update on the safety of sildenafil citrate (Viagra).

1 reference

12 December 2020

Effects of sildenafil citrate on human hemodynamics.

1 reference

12 December 2020

Pharmacological management of erectile dysfunction

1 reference

12 December 2020

Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy. Sildenafil Study Group

1 reference

12 December 2020

Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons

1 reference

12 December 2020

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial

1 reference

12 December 2020

PDE5 is converted to an activated state upon cGMP binding to the GAF A domain

1 reference

12 December 2020

Sildenafil for primary pulmonary hypertension: short and long-term symptomatic benefit.

1 reference

12 December 2020

The New England Journal of Medicine

12

324

1801

TF Lue

2000

1 reference

Crossref

https://api.crossref.org/works/10.1007/S11934-003-0027-X

2 April 2024

Identifiers

1 reference

9 August 2017

1 reference