(Q35586711)

9 August 2017

title

p21WAF1 expression in invasive breast cancer and its association with p53, AP-2, cell proliferation, and prognosis (English)

1 reference

9 August 2017

M J Pellikainen

1

1 reference

9 August 2017

T T Pekola

2

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9 August 2017

K M Ropponen

3

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9 August 2017

V V Kataja

4

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9 August 2017

J K Kellokoski

5

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9 August 2017

M J Eskelinen

6

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9 August 2017

V-M Kosma

7

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9 August 2017

language of work or name

English

0 references

publication date

1 March 2003

1 reference

Journal of Clinical Pathology

9 August 2017

published in

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9 August 2017

volume

56

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9 August 2017

issue

3

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9 August 2017

page(s)

214-220

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Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts

9 August 2017

cites work

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12 July 2018

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12 July 2018

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Quantitative p21(waf-1)/p53 immunohistochemical analysis defines groups of primary invasive breast carcinomas with different prognostic indicators

12 July 2018

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12 July 2018

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p(21WAF1/CIP1) expression in breast cancers: associations with p53 and outcome

12 July 2018

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Clinical relevance of immunohistochemical expression of p53-targeted gene products mdm-2, p21 and bcl-2 in breast carcinoma

12 July 2018

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Expression of transcription factor AP-2alpha predicts survival in epithelial ovarian cancer

12 July 2018

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Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer

12 July 2018

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p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis

12 July 2018

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p21(WAF1) expression and endocrine response in breast cancer

12 July 2018

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p21/WAF1 expression as related to p53, cell proliferation and prognosis in epithelial ovarian cancer

12 July 2018

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Activity and nature of p21(WAF1) complexes during the cell cycle

12 July 2018

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p21waf1/cip1 and transforming growth factor beta 1 protein expression correlate with survival in non-small cell lung cancer.

12 July 2018

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p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells

12 July 2018

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Induction of p21 (CIP1/WAF1/SID1) by estradiol in a breast epithelial cell line transfected with the recombinant estrogen receptor gene: a possible mechanism for a negative regulatory role of estradiol

12 July 2018

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Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

12 July 2018

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Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

12 July 2018

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Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

12 July 2018

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Absence of p21 expression is associated with abnormal p53 in human breast carcinomas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Identification of ERF-1 as a member of the AP2 transcription factor family

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

p21WAF1 immunohistochemical expression in breast carcinoma: correlations with clinicopathological data, oestrogen receptor status, MIB1 expression, p53 gene and protein alterations and relapse-free survival

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

WAF1, a potential mediator of p53 tumor suppression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

12 July 2018

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Statistical aspects of prognostic factor studies in oncology

12 July 2018

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Induction of WAF1/CIP1 by a p53-independent pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Constitutive expression of B-myb can bypass p53-induced Waf1/Cip1-mediated G1 arrest

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesio

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Abrogation of p53-induced cell cycle arrest by c-Myc: evidence for an inhibitor of p21WAF1/CIP1/SDI1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Glutathione S-transferase M1, M3, P1, and T1 genetic polymorphisms and susceptibility to breast cancer.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Downregulation of transcription factor AP-2 predicts poor survival in stage I cutaneous malignant melanoma.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Prognostic value of p21(WAF1) and p53 expression in breast carcinoma: an immunohistochemical study in 261 patients with long-term follow-up.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Increased level of p21 in human ovarian tumors is associated with increased expression of cdk2, cyclin A and PCNA.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

p21WAF1/Cip1 is associated with cyclin D1CCND1 expression and tubular differentiation but is independent of p53 overexpression in human breast carcinoma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

Polymorphic catechol-O-methyltransferase gene and breast cancer risk

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1769912

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

24 October 2018

1 reference

12 December 2020

Elevated levels of p27, p21 and cyclin D1 correlate with positive oestrogen and progesterone receptor status in node-negative breast carcinoma patients

1 reference

12 December 2020

Prognostic value of simultaneous expression of p21 and mdm2 in breast carcinomas treated by adjuvant chemotherapy with antracyclin

1 reference

12 December 2020

Loss of p21Waf1 expression is a strong predictor of reduced survival in primary superficial bladder cancers

1 reference

12 December 2020

p53 and p21waf-1 expression correlates with apoptosis or cell survival in poorly differentiated, but not well-differentiated, retinoblastomas

1 reference

12 December 2020

RB regulates transcription of the p21/WAF1/CIP1 gene

1 reference

12 December 2020

Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo

1 reference

12 December 2020

Expression of p21(WAF1/CIP1) and p53 proteins in gastric carcinoma: its relationships with cell proliferation activity and prognosis

1 reference

12 December 2020

p21/WAF1/Cip1 expression in invasive ductal breast carcinoma: relationship to p53, proliferation rate, and survival at 5 years

1 reference

12 December 2020

EGF-R expression in ductal breast cancer: proliferation and prognostic implications

1 reference

12 December 2020

Relationship between abnormal p53 protein and failure to express p21 protein in human breast carcinomas

1 reference

12 December 2020

WAF1/CIP1 protein expression in human breast tumors

1 reference

12 December 2020

p21(Waf1/Cip1) and p53 protein expression in breast cancer

1 reference

12 December 2020

p53 protein expression in breast carcinomas. Comparative study with the wild type p53 induced proteins mdm2 and p21/waf1

1 reference

12 December 2020

Aberrant p21(CIP1/WAF1) protein accumulation in head-and-neck cancer

1 reference

12 December 2020

p21/waf1/cip1 and mdm-2 expression in breast carcinoma patients as related to prognosis

1 reference

12 December 2020

Correlations between p21 expression and clinicopathological findings, p53 gene and protein alterations, and survival in patients with endometrial carcinoma

1 reference

12 December 2020

p53 Gene alterations and p53 protein accumulation in infiltrating ductal breast carcinomas: correlation between immunohistochemical and molecular biology techniques

1 reference

12 December 2020

Induction of p21 (WAF-1/CIP1) during differentiation

1 reference

12 December 2020

Identifiers

DOI

10.1136/JCP.56.3.214

1 reference

9 August 2017

1 reference

9 August 2017

1 reference