(Q35588998)

9 August 2017

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title

Endothelial dysfunction in obesity and insulin resistance: a road to diabetes and heart disease (English)

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9 August 2017

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A Enrique Caballero

1

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9 August 2017

language of work or name

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1 November 2003

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9 August 2017

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9 August 2017

volume

11

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9 August 2017

issue

11

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9 August 2017

page(s)

1278-1289

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Prevalence and Trends in Obesity Among US Adults, 1999-2000

9 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

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Central role of the adipocyte in insulin resistance

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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

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Adipokines, inflammation, and the endothelium in diabetes

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Role of insulin resistance in human disease (syndrome X): an expanded definition

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Atherosclerosis — An Inflammatory Disease

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Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

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Obesity and insulin resistance

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Pre-diabetes, insulin resistance, inflammation and CVD risk

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Obesity and risk of type 2 diabetes and cardiovascular disease in children and adolescents

21 January 2018

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Contributions of insulin-resistance and insulin-secretory defects to the pathogenesis of type 2 diabetes mellitus

21 January 2018

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Endothelial function in health and disease: new insights into the genesis of cardiovascular disease

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Microvascular function in human diabetes. A physiological perspective

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Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis

21 January 2018

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Soluble intercellular adhesion molecule, vascular cell adhesion molecule, and impaired microvascular reactivity are early markers of vasculopathy in type 2 diabetic individuals without microalbuminuria

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Estrogen improves endothelial function

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Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes

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Impaired endothelium-dependent vasodilatation in women with previous gestational diabetes.

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Early activation of vascular endothelium in nonobese, nondiabetic essential hypertensive patients with multiple metabolic abnormalities.

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Polycystic ovary syndrome is associated with endothelial dysfunction

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The role of TNFalpha and TNF receptors in obesity and insulin resistance

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Direct antidiabetic effect of leptin through triglyceride depletion of tissues.

21 January 2018

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The hormone resistin links obesity to diabetes

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Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle

21 January 2018

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

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Vascular function, insulin resistance and fatty acids

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Elevated serum TNF-alpha level as a link between endothelial dysfunction and insulin resistance in normotensive obese patients.

21 January 2018

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Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?

21 January 2018

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C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?

21 January 2018

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Inflammation and atherosclerosis

21 January 2018

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Hyperinsulinemia as an independent risk factor for ischemic heart disease.

21 January 2018

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Insulin sensitivity and atherosclerosis. The Insulin Resistance Atherosclerosis Study (IRAS) Investigators.

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Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

21 January 2018

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Insulin action in vascular endothelium: potential mechanisms linking insulin resistance with hypertension

21 January 2018

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Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

21 January 2018

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Insulin signaling in the arterial wall

21 January 2018

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Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

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Insulin causes endothelial dysfunction in humans: sites and mechanisms.

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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

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Crosstalk between insulin and angiotensin II signalling systems

21 January 2018

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Endothelial nitric oxide synthase gene is positively associated with essential hypertension.

21 January 2018

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Endothelial dysfunction: cause of the insulin resistance syndrome

21 January 2018

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Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year

21 January 2018

1 reference

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The effect of weight loss with or without exercise training on large artery compliance in healthy obese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Weight loss in combination with physical activity improves endothelial dysfunction in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Lifestyle modification improves endothelial function in obese subjects with the insulin resistance syndrome

21 January 2018

1 reference

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Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

21 January 2018

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Unraveling the mechanism of action of thiazolidinediones

21 January 2018

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Expression and function of PPARgamma in rat and human vascular smooth muscle cells

21 January 2018

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Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells

21 January 2018

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Control of vascular cell proliferation and migration by PPAR-gamma: a new approach to the macrovascular complications of diabetes

21 January 2018

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21 January 2018

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The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: a placebo-controlled randomized clinical trial

21 January 2018

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Antiinflammatory and antiarteriosclerotic effects of pioglitazone

21 January 2018

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Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus

21 January 2018

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Metabolic and additional vascular effects of thiazolidinediones.

21 January 2018

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Pioglitazone reduces urinary podocyte excretion in type 2 diabetes patients with microalbuminuria

21 January 2018

1 reference

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Rosiglitazone reduces urinary albumin excretion in type II diabetes

21 January 2018

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Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Decreased mortality associated with the use of metformin compared with sulfonylurea monotherapy in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

The effects of high- and medium-dose metformin therapy on cardiovascular risk factors in patients with type II diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Improved endothelial function with metformin in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Effect of weight change and metformin on fibrinolysis and the von Willebrand factor in obese nondiabetic subjects: the BIGPRO1 Study. Biguanides and the Prevention of the Risk of Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Insulin Sensitivity, Vascular Reactivity, and Clamp-Induced Vasodilatation in Essential Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Overweight and obesity in the United States: prevalence and trends, 1960-1994

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Endothelial dysfunction in the early stage of atherosclerosis precedes appearance of intimal lesions assessable with intravascular ultrasound

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Reactive hyperemic response of the brachial artery: comparison of proximal and distal occlusion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Type II diabetes abrogates sex differences in endothelial function in premenopausal women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Relation of hypertriglyceridemia to plasma concentrations of biochemical markers of inflammation and endothelial activation (C-reactive protein, interleukin-6, soluble adhesion molecules, von Willebrand factor, and endothelin-1)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Leptin induces direct vasodilation through distinct endothelial mechanisms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Relationship between endothelin-1 concentration and metabolic alterations typical of the insulin resistance syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Dissociation between insulin sensitivity of glucose uptake and endothelial function in normal subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2003.174

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/OBY.2003.174

1 reference

9 August 2017

1 reference