(Q35591810)

9 August 2017

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title

Involvement of growth factors in thymic involution (English)

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9 August 2017

Olivia García-Suárez

1

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9 August 2017

Marta Pérez-Pérez

2

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9 August 2017

Antonino Germanà

3

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9 August 2017

Isabel Esteban

4

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9 August 2017

Giovanni Germanà

5

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9 August 2017

publication date

1 December 2003

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Microscopy Research and Technique

9 August 2017

published in

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9 August 2017

volume

62

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9 August 2017

issue

6

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9 August 2017

page(s)

514-523

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Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

9 August 2017

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Il-7 and not stem cell factor reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice.

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Thymic atrophy in the mouse is a soluble problem of the thymic environment.

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The effect of in vivo IL-7 deprivation on T cell maturation

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Repopulation of the atrophied thymus in diabetic rats by insulin-like growth factor I.

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Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division

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IL-7 receptor and VDJ recombination: trophic versus mechanistic actions

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Cytokines in T-cell development

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Evidence for thymic function in the elderly

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Plasticity of neuroendocrine-thymus interactions during aging.

21 January 2018

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Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space

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Expression of the TrkB neurotrophin receptor by thymic macrophages

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The human thymus during aging

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Modulation of dye-coupling and proliferation in cultured rat thymic epithelium by factors involved in thymulin secretion.

21 January 2018

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Hypothalamic control of development and aging of the thymus.

21 January 2018

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Neurotrophins: roles in neuronal development and function

21 January 2018

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Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues

21 January 2018

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Insulin-like growth factors I and II.

21 January 2018

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Generation of functional thymocytes in the human adult.

21 January 2018

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The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

21 January 2018

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Characterization of the insulin-like growth factor axis in the human thymus

21 January 2018

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Growth hormone, prolactin, and insulin-like growth factors: new jobs for old players

21 January 2018

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Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics

21 January 2018

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Insulin growth factor-I inhibits apoptosis in hematopoietic progenitor cells. Implications in thymic aging

21 January 2018

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Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?

21 January 2018

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Sex hormones as negative regulators of lymphopoiesis

21 January 2018

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The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Type I insulin-like growth factor receptor expression in different developmental stages of human thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Polymorphism of age-related changes in interleukin (IL) production: differential changes of T helper subpopulations, synthesizing IL 2, IL 3 and IL 4.

21 January 2018

1 reference

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trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

21 January 2018

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Human thymic epithelial cells: adhesion molecules and cytokine production

21 January 2018

1 reference

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Regulation of cytokine production in the human thymus: epidermal growth factor and transforming growth factor alpha regulate mRNA levels of interleukin 1 alpha (IL-1 alpha), IL-1 beta, and IL-6 in human thymic epithelial cells at a post-transcriptio

21 January 2018

1 reference

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The brain and thymus have much in common: a functional analysis of their microenvironments

21 January 2018

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Acute insulin action requires insulin receptor kinase activity: introduction of an inhibitory monoclonal antibody into mammalian cells blocks the rapid effects of insulin

21 January 2018

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https://api.crossref.org/works/10.1002%2FJEMT.10413

Definition of unique traits of human CD4-CD8- alpha beta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Induction of TCR gene rearrangements in uncommitted stem cells by a subset of IL-7 producing, MHC class-II-expressing thymic stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Neurotrophins and cytokines--intermediaries between the immune and nervous systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Expression of NGF receptors in normal and pathological human thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Development in the thymus: it takes two to tango

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Epidermal growth factor promotes a neural phenotype in thymic epithelial cells and enhances neuropoietic cytokine expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Autocrine secretion--10 years later

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Burnet oration. T-cell survival and the role of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Pleiotropic functions of neurotrophins in development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

The pattern of T lymphocyte differentiation is altered during thymic involution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Receptors for nerve growth factor on rat spleen mononuclear cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Widespread and developmentally regulated expression of neurotrophin-4 mRNA in rat brain and peripheral tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Functional receptors for insulin-like growth factors I and II in rat thymocytes and mouse thymoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Catecholamines and lipopolysaccharide synergistically induce the release of interleukin-6 from thymic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Effect of transmitters and co-transmitters of the sympathetic nervous system on interleukin-6 synthesis in thymic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Molecular analysis of signal transduction by growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

The murine thymic microenvironment: changes with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Cytokines and Neurotrophins Interact in Normal and Diseased States

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

The immunomodulatory effect of nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Age-associated thymic atrophy is linked to a decline in IL-7 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Enhancement of thymic recovery after cyclosporine by recombinant human growth hormone and insulin-like growth factor I

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Decline in the production of interleukin-3 with age in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Aging of the recipients but not of the bone marrow donors enhances autoimmunity in syngeneic radiation chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Cellular Determinants of Age-related Decrements in the T-cell Mitogen Response of B6CBAF1 Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Changes in the expression of the nerve growth factor receptors TrkA and p75LNGR in the rat thymus with ageing and increased nerve growth factor plasma levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

TrkA is necessary for the normal development of the murine thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Massive lymphocyte apoptosis in the thymus of functionally deficient TrkB mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

TrkA neutrophin receptor protein in the rat and human thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Understanding the mechanism of the age-change of thymic function to promote T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Polypeptide growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Tissue distribution and immunocytochemical localization of neurotrophin-3 in the brain and peripheral tissues of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Involvement of insulin-like growth factors in early T cell development: a study using fetal thymic organ cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Distribution of NGF receptors in normal and pathologic human lymphoid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

The endocrinology of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Expression of mRNA encoding neurotrophins and neurotrophin receptors in rat thymus, spleen tissue and immunocompetent cells. Regulation of neurotrophin-4 mRNA expression by mitogens and leukotriene B4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

The effects of growth hormone and insulin-like growth factor I on the immune system of aged female monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Neurotrophin receptor-like proteins in the bovine (Bos taurus) lymphoid organs, with special reference to thymus and spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

The Role of Thymocytes in Regulating Thymic Epithelial Cell Growth and Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Ultrastructural study of thymic microenvironment involution in aging mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Expression of interleukin-1 receptors in the later period of foetal thymic organ culture and during suspension culture of thymocytes from aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Molecular characterization of the mouse involuted thymus: aberrations in expression of transcription regulators in thymocyte and epithelial compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Expression of epidermal and nerve growth factor receptors in human thymus and thymomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Expression of protein tyrosine kinases in the murine thymus stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Human thymic epithelial cells produce TGF-beta 3 and express TGF-beta receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Aging and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Expression of insulin-like growth factor II (IGF-II) and histological changes in the thymus and spleen of transgenic mice overexpressing IGF-II

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

Localization of neurotrophin-3-like immunoreactivity in peripheral tissues of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10413

21 January 2018

Identifiers

DOI

10.1002/JEMT.10413

1 reference

9 August 2017

1 reference