(Q35593949)

9 August 2017

1 reference

title

11beta-hydroxysteroid dehydrogenase type 1 as a novel therapeutic target in metabolic and neurodegenerative disease (English)

1 reference

9 August 2017

1 reference

Brian R Walker

1

1 reference

9 August 2017

Jonathan R Seckl

series ordinal

2

1 reference

9 August 2017

language of work or name

English

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publication date

1 December 2003

1 reference

Expert Opinion on Therapeutic Targets

9 August 2017

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9 August 2017

7

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9 August 2017

6

1 reference

9 August 2017

771-783

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Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

9 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Morbidity and mortality in Cushing's disease: an epidemiological approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Antiglucocorticoid drugs in the treatment of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Hypothalamic arousal, insulin resistance and Type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Cortisol levels during human aging predict hippocampal atrophy and memory deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Antiglucocorticoid treatment of depression: double-blind ketoconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Nonsteroidal selective glucocorticoid modulators: the effect of C-5 alkyl substitution on the transcriptional activation/repression profile of 2,5-dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Nonsteroidal selective glucocorticoid modulators: the effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Novel aspects of hormone action: intracellular ligand supply and its control by a series of tissue specific enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

11beta-hydroxysteroid dehydrogenase type 2 in mouse aorta: localization and influence on response to glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Does central obesity reflect "Cushing's disease of the omentum"?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

11 Beta-hydroxysteroid dehydrogenase type 1 from human liver: dimerization and enzyme cooperativity support its postulated role as glucocorticoid reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Comparative enzymology of 11 beta -hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (Guinea pig) versus sensitive (human) species

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Prereceptor regulation of glucocorticoid action by 11beta-hydroxysteroid dehydrogenase: a novel determinant of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

A transgenic model of visceral obesity and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Mild cognitive impairment: conceptual basis and current nosological status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Independent effects of obesity and cortisol in predicting cardiovascular risk factors in men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

11 beta-Hydroxysteroid dehydrogenase activity in hypothalamic obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Tissue-specific dysregulation of cortisol metabolism in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Subcutaneous adipose 11 beta-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Polyglandular autoimmune syndromes: immunogenetics and long-term follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Mineralocorticoid activity of liquorice: 11-beta-hydroxysteroid dehydrogenase deficiency comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

The effects of the licorice derivative, glycyrrhetinic acid, on hepatic 3 alpha- and 3 beta-hydroxysteroid dehydrogenases and 5 alpha- and 5 beta-reductase pathways of metabolism of aldosterone in male rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

K+ currents underlying the action of endothelium-derived hyperpolarizing factor in guinea-pig, rat and human blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Critical role of gap junctions in endothelium-dependent hyperpolarization in rat mesenteric arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Differential inhibition of 11 beta-hydroxysteroid dehydrogenase by carbenoxolone in rat brain regions and peripheral tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Foetal lung maturation in 11beta-hydroxysteroid dehydrogenase type 1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

11beta-hydroxysteroid dehydrogenase type 1: a new regulator of fetal lung maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11beta-hydroxysteroid dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by proinflammatory cytokines in osteoblasts: an autocrine switch from glucocorticoid inactivation to activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Regulation of 11beta-hydroxysteroid dehydrogenase type 1 gene expression by LH and interleukin-1beta in cultured rat granulosa cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Induction of 11beta-hydroxysteroid dehydrogenase type 1 but not -2 in human aortic smooth muscle cells by inflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Effects of glycyrrhetinic acid derivatives on hepatic and renal 11beta-hydroxysteroid dehydrogenase activities in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Possible endogenous regulators of steroid inactivating enzymes and glucocorticoid-induced Na+ retention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Ovarian modulators of 11beta-hydroxysteroid dehydrogenase (11beta HSD) activity in follicular fluid from bovine and porcine large antral follicles and spontaneous ovarian cysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Bile acids and their amidates inhibit 11 beta-hydroxysteroid dehydrogenase obtained from rat kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

A novel 11 beta-hydroxysteroid dehydrogenase inhibitor contained in saiboku-to, a herbal remedy for steroid-dependent bronchial asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Furosemide inhibits 11beta-hydroxysteroid dehydrogenase type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Furosemide and 11beta-hydroxysteroid dehydrogenase activity, in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Grapefruit juice inhibits 11beta-hydroxysteroid dehydrogenase in vivo, in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

Blood pressure in adults after prenatal exposure to famine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.6.771

21 January 2018

Identifiers

DOI

10.1517/14728222.7.6.771

1 reference

release_qzigym2tl5dmvjq7nusuih7wvi

9 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qzigym2tl5dmvjq7nusuih7wvi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference