(Q35595694)

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Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging

scientific article published on 20 October 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Andrea C Gore

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Deena M Walker

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Aparna M Zama

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

AnnMarie E Armenti

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Mehmet Uzumcu

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

20 October 2011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Molecular Endocrinology

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2157-2168

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Genome-wide profiling of H3K56 acetylation and transcription factor binding sites in human adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Prenatal PCBs disrupt early neuroendocrine development of the rat hypothalamus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor beta and AP-1 recruitment to adjacent promoter binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Endocrine disruption of brain sexual differentiation by developmental PCB exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

The hypothalamic median eminence and its role in reproductive aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Developmental and hormone-induced epigenetic changes to estrogen and progesterone receptor genes in brain are dynamic across the life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Developmental programming: impact of fetal exposure to endocrine-disrupting chemicals on gonadotropin-releasing hormone and estrogen receptor mRNA in sheep hypothalamus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Epigenetic effects of endocrine-disrupting chemicals on female reproduction: an ovarian perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence of female rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Neuroendocrine targets of endocrine disruptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

The neurobiology of preovulatory and estradiol-induced gonadotropin-releasing hormone surges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Sex differences in epigenetic regulation of the estrogen receptor-alpha promoter within the developing preoptic area

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Exposure to a complex cocktail of environmental endocrine-disrupting compounds disturbs the kisspeptin/GPR54 system in ovine hypothalamus and pituitary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Kisspeptin signaling in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Neonatal bisphenol-a exposure alters rat reproductive development and ovarian morphology without impairing activation of gonadotropin-releasing hormone neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Endocrine-disrupting chemicals: an Endocrine Society scientific statement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

The excitatory peptide kisspeptin restores the luteinizing hormone surge and modulates amino acid neurotransmission in the medial preoptic area of middle-aged rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Developmental methoxychlor exposure affects multiple reproductive parameters and ovarian folliculogenesis and gene expression in adult rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Disrupted female reproductive physiology following neonatal exposure to phytoestrogens or estrogen specific ligands is associated with decreased GnRH activation and kisspeptin fiber density in the hypothalamus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Kisspeptin signalling in the brain: steroid regulation in the rodent and ewe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Age at natural menopause in women exposed to diethylstilbestrol in utero

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Serum dioxin concentrations and age at menopause

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27 July 2018

Epigenetic transgenerational actions of endocrine disruptors and male fertility

1 reference

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27 July 2018

Age at natural menopause and exposure to organochlorine pesticides in Hispanic women

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Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARbeta activity

1 reference

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27 July 2018

Bisphenol a exposure causes meiotic aneuploidy in the female mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

27 July 2018

Ethological methods to study the effects of maternal exposure to estrogenic endocrine disrupters: a study with methoxychlor.

1 reference

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27 July 2018

A high affinity HSF-1 binding site in the 5'-untranslated region of the murine tumor necrosis factor-alpha gene is a transcriptional repressor

1 reference

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27 July 2018

Alterations in hypothalamic insulin-like growth factor-I and its associations with gonadotropin releasing hormone neurones during reproductive development and ageing

1 reference

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27 July 2018

Glia-to-neuron signaling and the neuroendocrine control of female puberty

1 reference

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The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing

1 reference

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ZF5, which is a Kruppel-type transcriptional repressor, requires the zinc finger domain for self-association

1 reference

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A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat.

1 reference

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Implications of early menopause in women exposed to perfluorocarbons.

1 reference

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26 September 2018

Intrauterine Position Affects Estrogen Receptor α Expression in the Ventromedial Nucleus of the Hypothalamus via Promoter DNA Methylation

1 reference

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26 September 2018

Glutamate regulation of GnRH neuron excitability

1 reference

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Sox9 represses alpha-sarcoglycan gene expression in early myogenic differentiation.

1 reference

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26 September 2018

Chapter 2: hypothalamic neural systems controlling the female reproductive life cycle gonadotropin-releasing hormone, glutamate, and GABA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

26 September 2018

Lasting epigenetic influence of early-life adversity on the BDNF gene

1 reference

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26 September 2018

Developmental profiles of neuroendocrine gene expression in the preoptic area of male rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3231835

26 September 2018

Early postnatal methoxychlor exposure inhibits folliculogenesis and stimulates anti-Mullerian hormone production in the rat ovary

1 reference

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Ovarian endocrine disruption underlies premature reproductive senescence following environmentally relevant chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin

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Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility.

1 reference

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26 September 2018

Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4

1 reference

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Impact of maternal dietary exposure to endocrine-acting chemicals on progesterone receptor expression in microdissected hypothalamic medial preoptic areas of rat offspring.

1 reference

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Effects of acute and chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin on the transition to reproductive senescence in female Sprague-Dawley rats

1 reference

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Genetic studies to identify genes underlying menopausal age.

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1 reference

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Menopausal increases in pulsatile gonadotropin-releasing hormone release in a nonhuman primate (Macaca mulatta).

1 reference

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Modulation of ovarian follicle maturation in Long–Evans rats exposed to polychlorinated biphenyls (PCBs) in-utero and lactationally

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Organochlorine exposure and age at natural menopause

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Menstruation and reproduction in women with polychlorinated biphenyl (PCB) poisoning: long-term follow-up interviews of the women from the Taiwan Yucheng cohort

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Effect of methoxychlor on implantation and embryo development in the mouse.

1 reference

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Methoxychlor as a model for environmental estrogens

1 reference

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Pesticide Exposure and Timing of Menopause

1 reference

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15 November 2018

The developmental origins of adult disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22016562

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in luteinizing hormone-releasing hormone release from the mediobasal hypothalamus of ovariectomized, steroid-primed middle-aged rats as measured by push-pull perfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22016562

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The decline of infertility: apparent or real?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22016562

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/ME.2011-1210

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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