(Q35597021)

9 August 2017

Increased epithelial uptake of protein antigens in the ileum of Crohn's disease mediated by tumour necrosis factor alpha (English)

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9 August 2017

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J D Söderholm

1

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9 August 2017

C Streutker

2

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9 August 2017

P-C Yang

3

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9 August 2017

C Paterson

4

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9 August 2017

P K Singh

5

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9 August 2017

D M McKay

6

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9 August 2017

P M Sherman

7

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9 August 2017

K Croitoru

8

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9 August 2017

M H Perdue

9

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9 August 2017

language of work or name

English

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publication date

1 December 2004

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9 August 2017

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9 August 2017

53

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9 August 2017

12

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9 August 2017

1817-1824

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CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

9 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Molecular structure of tight junctions and their role in epithelial transport.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Monocyte/macrophage activation by normal bacteria and bacterial products: implications for altered epithelial function in Crohn's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Regulation of intercellular tight junctions by zonula occludens toxin and its eukaryotic analogue zonulin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Molecular physiology and pathophysiology of tight junctions III. Tight junction regulation by intracellular messengers: differences in response within and between epithelia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Strictures in Crohn's disease are characterised by an accumulation of mast cells colocalised with laminin but not with fibronectin or vitronectin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Immune-epithelial interactions in host defense.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Transepithelial transport processes at the intestinal mucosa in inflammatory bowel disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: an inherited defect in mucosal defence?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Monocyte/macrophages evoke epithelial dysfunction: indirect role of tumor necrosis factor-alpha.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Integrity and metabolism of human ileal mucosa in vitro in the Ussing chamber

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Review article: Intestinal permeability in Crohn's disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Clustering of increased small intestinal permeability in families with Crohn's disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Mononuclear cells from infants allergic to cow's milk secrete tumor necrosis factor alpha, altering intestinal function.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Intestinal permeability: an overview

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

CD45RO expression on circulating CD19+ B cells in Crohn's disease correlates with intestinal permeability

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Glomerular permeability. Ultrastructural cytochemical studies using peroxidases as protein tracers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Bryostatin-1 attenuates TNF-induced epithelial barrier dysfunction: role of novel PKC isozymes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Supernatants of HIV-infected immune cells affect the barrier function of human HT-29/B6 intestinal epithelial cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Mast cells are an important cellular source of tumour necrosis factor alpha in human intestinal tissue

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn's ileocolitis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Current concepts in mucosal immunity. I. Antigen presentation in the intestine: new rules and regulations

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Superantigen activation of immune cells evokes epithelial (T84) transport and barrier abnormalities via IFN-gamma and TNF alpha: inhibition of increased permeability, but not diminished secretory responses by TGF-beta2.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

5-Aminosalicylic acid inhibits the impaired epithelial barrier function induced by gamma interferon

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774309

Subclinical intestinal inflammation: an inherited abnormality in Crohn’s disease relatives?

26 September 2018

1 reference

12 December 2020

Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

12 December 2020

Mucosal injury and inflammation in a model of chronic granulomatous colitis in rats

1 reference

12 December 2020

Is small intestinal permeability really increased in relatives of patients with Crohn's disease?

1 reference

12 December 2020

Changes in small-intestine permeability with aging

1 reference

12 December 2020

Budesonide inhibits T cell-initiated epithelial pathophysiology in an in vitro model of inflammation

1 reference

12 December 2020

Intestinal permeability changes in response to acetylsalicylic acid in relatives of patients with Crohn's disease

1 reference

12 December 2020

Enhanced absorption of macromolecules. A secondary factor in Crohn's disease

1 reference

12 December 2020

Rapid transepithelial antigen transport in rat jejunum: impact of sensitization and the hypersensitivity reaction

1 reference

12 December 2020

The influence of mast cells on pathways of transepithelial antigen transport in rat intestine

1 reference

12 December 2020

Stress stimulates transepithelial macromolecular uptake in rat jejunum

1 reference

12 December 2020

Modulation of antigen trafficking to MHC class II-positive late endosomes of enterocytes

1 reference

12 December 2020

Tumor necrosis factor-alpha in ileal mast cells in patients with Crohn's disease

1 reference

12 December 2020

Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitis

1 reference

12 December 2020

Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

1 reference

12 December 2020

Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trial

1 reference

12 December 2020

Epithelial permeability to proteins in the noninflamed ileum of Crohn's disease?

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.2004.041426

1 reference

9 August 2017

1 reference

9 August 2017

1 reference