(Q35598807)

English

Mutant BRAF induces DNA strand breaks, activates DNA damage response pathway, and up-regulates glucose transporter-1 in nontransformed epithelial cells

scientific article published on 5 January 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Mutant BRAF induces DNA strand breaks, activates DNA damage response pathway, and up-regulates glucose transporter-1 in nontransformed epithelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

0 references

author name string

Jim Jinn-Chyuan Sheu

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Bin Guan

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Fuu-Jen Tsai

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Erin Yi-Ting Hsiao

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Chih-Mei Chen

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Raquel Seruca

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Tian-Li Wang

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Ie-Ming Shih

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

0 references

publication date

5 January 2012

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

180

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1179-1188

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Low-grade serous carcinomas of the ovary contain very few point mutations

1 reference

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

1 reference

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Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse

1 reference

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Targeting BRAF in advanced melanoma: a first step toward manageable disease

1 reference

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Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target?

1 reference

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Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability.

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GLUT1 as a therapeutic target in hepatocellular carcinoma

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A dimerization-dependent mechanism drives RAF catalytic activation

1 reference

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Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

1 reference

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The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

1 reference

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Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas

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Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

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12 July 2018

KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer

1 reference

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A microRNA component of the p53 tumour suppressor network

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12 July 2018

A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

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12 July 2018

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

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12 July 2018

Sustained expression of Mect1-Maml2 is essential for tumor cell growth in salivary gland cancers carrying the t(11;19) translocation

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12 July 2018

Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas

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12 July 2018

BRAF mutation predicts sensitivity to MEK inhibition

1 reference

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Antioxidants prevent oxidative DNA damage and cellular transformation elicited by the over-expression of c-MYC.

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

1 reference

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

1 reference

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Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations

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DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells

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Cell-cycle checkpoints and cancer

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BRAF as a potential therapeutic target in melanoma and other malignancies

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ATM and related protein kinases: safeguarding genome integrity

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Targeting RAS signalling pathways in cancer therapy

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Mutations of the BRAF gene in human cancer

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Surfing the p53 network

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Identifiers

10.1016/J.AJPATH.2011.11.026

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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