(Q35604954)

9 August 2017

title

The chromatin-binding protein HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2) and affects the behavior of mice (English)

1 reference

9 August 2017

Liron Abuhatzira

1

1 reference

9 August 2017

Alon Shamir

2

1 reference

9 August 2017

Dustin E Schones

3

1 reference

9 August 2017

Alejandro A Schäffer

4

1 reference

9 August 2017

Michael Bustin

5

1 reference

9 August 2017

language of work or name

English

0 references

publication date

17 October 2011

1 reference

Journal of Biological Chemistry

9 August 2017

published in

1 reference

9 August 2017

volume

286

1 reference

9 August 2017

issue

49

1 reference

9 August 2017

page(s)

42051-42062

1 reference

Protein interactome reveals converging molecular pathways among autism disorders

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Effects of HMGN variants on the cellular transcription profile

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Regions of homozygosity and their impact on complex diseases and traits

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Down syndrome: from understanding the neurobiology to therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Distinct disorders affecting the brain share common genetic origins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

A genome-wide scan for common alleles affecting risk for autism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Autism spectrum disorders and epigenetics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Behavioural phenotyping assays for mouse models of autism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Brain function and chromatin plasticity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Functional impact of global rare copy number variation in autism spectrum disorders

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Disruption of the epigenetic code: an emerging mechanism in mental retardation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Binding and interplay of HMG proteins on chromatin: lessons from live cell imaging.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

The dynamics of HMG protein-chromatin interactions in living cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

MeCP2 involvement in the regulation of neuronal alpha-tubulin production

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

MeCP2, a key contributor to neurological disease, activates and represses transcription

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

PLINK: a tool set for whole-genome association and population-based linkage analyses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

The challenge of Down syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Identification of cis-regulatory elements for MECP2 expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Identification of MeCP2 mutations in a series of females with autistic disorder

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Competition between histone H1 and HMGN proteins for chromatin binding sites.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

CpG methylation, chromatin structure and gene silencing-a three-way connection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: altered behavior in the elevated plus maze and open field

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

The HMG-14/-17 chromosomal protein family: architectural elements that enhance transcription from chromatin templates

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Homodimers of chromosomal proteins HMG-14 and HMG-17 in nucleosome cores

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Immunochemical analysis of the exposure of high mobility group protein 14 and 17 surfaces in chromatin.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Immunological relatedness of high mobility group chromosomal proteins from calf thymus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

27 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Expression of the congenital heart disease 5/tryptophan rich basic protein homologue gene during heart development in medaka fish, Oryzias latipes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Regulation of chromatin structure and function by HMGN proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Chromosomal protein HMGN1 modulates histone H3 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Stimulation of RNA polymerase II elongation by chromosomal protein HMG-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Mapping of the Down syndrome phenotype on chromosome 21 at the molecular level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Genomic profiling of HMGN1 reveals an association with chromatin at regulatory regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Binding of the Rett syndrome protein, MeCP2, to methylated and unmethylated DNA and chromatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

The MECP2 duplication syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Common genetic variants on 5p14.1 associate with autism spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Summaries of the Sixth Annual Poster Session of the American Psychoanalytic Association: part I. Triangular relationships in adolescence predict adult psychopathology: an empirical validation of the Oedipus complex?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

The methyl-CpG-binding protein MeCP2 and neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (Formaldehyde Assisted Isolation of Regulatory Elements).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Automated apparatus for quantitation of social approach behaviors in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.300541

Persistence of chromosomal proteins HMG-14/-17 in myotubes following differentiation-dependent reduction of HMG mRNA

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234940

Distinct domains in high mobility group N variants modulate specific chromatin modifications

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22009741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The parallel rod floor test: a measure of ataxia in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22009741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.300541

1 reference

release_rfuhz6yplbh2ho7si3uif4zmdm

9 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rfuhz6yplbh2ho7si3uif4zmdm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3234940

1 reference

9 August 2017

1 reference