(Q35610300)

9 August 2017

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title

Clinical trials with retrovirus mediated gene therapy--what have we learned? (English)

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9 August 2017

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Nikolai G Rainov

1

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9 August 2017

Huan Ren

series ordinal

2

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9 August 2017

language of work or name

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1 December 2003

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Journal of Neuro-Oncology

9 August 2017

published in

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9 August 2017

volume

65

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9 August 2017

issue

3

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9 August 2017

page(s)

227-236

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Gene therapy for brain tumors

9 August 2017

cites work

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12 December 2020

Molecular evaluation of biopsy and autopsy specimens from patients receiving in vivo retroviral gene therapy

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12 December 2020

Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patients with glioblastoma multiforme.

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12 December 2020

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy

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12 December 2020

In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats

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12 December 2020

Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells

1 reference

12 December 2020

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

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12 December 2020

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

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12 December 2020

Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions

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12 December 2020

Biosafety monitoring of patients receiving intracerebral injections of murine retroviral vector producer cells

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12 December 2020

Retrovirus-mediated gene transfer in cancer therapy

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12 December 2020

Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors

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12 December 2020

Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas

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12 December 2020

Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses

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12 December 2020

Efficient gene transfer of VSV-G pseudotyped retroviral vector to human brain tumor

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12 December 2020

Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

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12 December 2020

Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses.

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12 December 2020

The retroviral vector. Replication cycle and safety considerations for retrovirus-mediated gene therapy.

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12 December 2020

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

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12 December 2020

Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells

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12 December 2020

Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors

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12 December 2020

Cell targeting with retroviral vector particles containing antibody-envelope fusion proteins

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12 December 2020

Generation of an anti-tumour immune response in a non-immunogenic tumour: HSVtk killing in vivo stimulates a mononuclear cell infiltrate and a Th1-like profile of intratumoural cytokine expression

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12 December 2020

Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy

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12 December 2020

Mechanism of 'bystander effect' killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment

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12 December 2020

Treatment of progressive or recurrent pediatric malignant supratentorial brain tumors with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration

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12 December 2020

Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.

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12 December 2020

Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene

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12 December 2020

Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

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12 December 2020

Acute neurologic dysfunction associated with high-dose chemotherapy and autologous bone marrow rescue for primary malignant brain tumors

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12 December 2020

In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

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12 December 2020

Biology and treatment of malignant glioma

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12 December 2020

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells

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12 December 2020

Distribution of retroviral vectors and vector producer cells using two routes of administration in rats

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12 December 2020

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

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12 December 2020

Chemotherapy of brain tumors

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12 December 2020

Vector delivery methods and targeting strategies for gene therapy of brain tumors

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12 December 2020

Enhanced expression of thymidine kinase in human cells following ionizing radiation.

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12 December 2020

Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ganciclovir paradigm

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12 December 2020

Paracrine delivery of IL-12 against intracranial 9L gliosarcoma in rats.

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12 December 2020

Gene therapy of rat 9L gliosarcoma tumors by transduction with selectable genes does not require drug selection

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12 December 2020

Cloning of two genetically transmitted Moloney leukemia proviral genomes: correlation between biological activity of the cloned DNA and viral genome activation in the animal

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12 December 2020

An improved retroviral vector encoding the herpes simplex virus thymidine kinase gene increases antitumor efficacy in vivo.

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12 December 2020

Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion

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12 December 2020

Transgene inheritance and retroviral infection contribute to the efficiency of gene expression in solid tumors inoculated with retroviral vector producer cells

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12 December 2020

A nucleoprotein complex mediates the integration of retroviral DNA.

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12 December 2020

A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group

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12 December 2020

Selective enhancement by an antiviral agent of the radiation-induced cell killing of human glioma cells transduced with HSV-tk gene

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12 December 2020

Human immunodeficiency virus infection of cells arrested in the cell cycle

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12 December 2020

Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans

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12 December 2020

Imaging transgene expression with radionuclide imaging technologies

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12 December 2020

Potential of gene therapy for brain tumors

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12 December 2020

Systemic activation of the immune system during ganciclovir treatment following intratumoral herpes simplex virus type 1 thymidine kinase gene transfer in an adolescent ependymoma patient.

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12 December 2020

Gene therapy in brain tumours: implications of the size of glioblastoma on its curability

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12 December 2020

Herpes simplex virus thymidine kinase as a marker/reporter gene for PET imaging of gene therapy.

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12 December 2020

Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors

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12 December 2020

Low efficacy of gene therapy for rat BT4C malignant glioma using intra-tumoural transduction with thymidine kinase retrovirus packaging cell injections and ganciclovir treatment

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12 December 2020

Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study

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12 December 2020

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

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12 December 2020

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

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12 December 2020

The effects of human serum and cerebrospinal fluid on retroviral vectors and packaging cell lines.

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12 December 2020

Construction and use of a safe and efficient amphotropic packaging cell line

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12 December 2020

Ganciclovir chemoablation of herpes thymidine kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses

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12 December 2020

Eradication of murine brain tumors by direct inoculation of concentrated high titer-recombinant retrovirus harboring the herpes simplex virus thymidine kinase gene

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12 December 2020

Generation of stable retrovirus packaging cell lines after transduction with herpes simplex virus hybrid amplicon vectors

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12 December 2020

A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma

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12 December 2020

Intravenous RMP-7 increases delivery of ganciclovir into rat brain tumors and enhances the effects of herpes simplex virus thymidine kinase gene therapy

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12 December 2020

Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line

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12 December 2020

Thymidine kinase-mediated killing of rat brain tumors

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12 December 2020

Immunomodulation of glioma cells after gene therapy: induction of major histocompatibility complex class I but not class II antigen in vitro

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12 December 2020

Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors

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12 December 2020

10.1023/B:NEON.0000003652.71665.F2

Identifiers

DOI

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Dimensions Publication ID

9 August 2017

1051407356

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