(Q35610323)

9 August 2017

title

Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease (English)

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9 August 2017

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hepatocellular carcinoma

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K Shii

1

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9 August 2017

R A Roth

series ordinal

2

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9 August 2017

language of work or name

English

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publication date

1 June 1986

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

volume

83

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9 August 2017

issue

12

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9 August 2017

page(s)

4147-4151

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Insulin metabolism and degradation

9 August 2017

cites work

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12 July 2018

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Insulin degradation by adipose tissue. Studies at several levels of cellular organization

12 July 2018

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12 July 2018

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12 July 2018

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Lipoprotein metabolism by rat hepatomas. Studies on the etiology of defective dietary feedback inhibition of cholesterol synthesis

12 July 2018

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Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen

12 July 2018

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Evidence for insulin degradation by muscle and fat tissue in an insulin resistant diabetic patient.

12 July 2018

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12 July 2018

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Apparent Insulin Resistance due to Abnormal Enzymatic Insulin Degradation: A New Mechanism for Insulin Resistance

12 July 2018

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In Vivo Chloroquine-induced Inhibition of Insulin Degradation in a Diabetic Patient with Severe Insulin Resistance

12 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

12 July 2018

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Purification of insulin-specific protease by affinity chromatography

12 July 2018

1 reference

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Characterization of an insulin degrading enzyme from cultured human lymphocytes

12 July 2018

1 reference

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Covalent linkage of 125I-insulin to a cytosolic insulin-degrading enzyme.

12 July 2018

1 reference

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Purification and characterization of a rat liver cytosol neutral thiol peptidase that degrades glucagon, insulin, and isolated insulin A and B chains.

12 July 2018

1 reference

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Effects of lysosomal inhibitors on 125I-insulin and 125I-asialofetuin degradation by the isolated, perfused rat liver and isolated rat hepatocytes

12 July 2018

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Uptake and degradation of insulin and alpha 2-macroglobulin-trypsin complex in rat adipocytes. Evidence for different pathways

12 July 2018

1 reference

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A better cell line for making hybridomas secreting specific antibodies

12 July 2018

1 reference

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Accelerated Insulin Degradation: An Alternate Mechanism for Insulin Resistance

12 July 2018

1 reference

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Internalization and degradation of fat cell-bound insulin. Separation and partial characterization of subcellular vesicles associated with iodoinsulin

12 July 2018

1 reference

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The Importance of Proteolysis as the Initial Step of Insulin Degradation in Rat Liver Homogenates*

12 July 2018

1 reference

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

12 July 2018

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The Banting Memorial Lecture 1976. Insulin today

12 July 2018

1 reference

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Initial site of insulin cleavage by insulin protease

12 July 2018

1 reference

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Receptor-mediated endocytosis: insights from the lipoprotein receptor system

12 July 2018

1 reference

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Binding and degradation of 125I-insulin by rat hepatocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=323688

Insulin and glucagon degradation by the kidney II. Characterization of the mechanisms at neutral pH

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=323688

Diabetes responsive to intravenous but not subcutaneous insulin: effectiveness of aprotinin.

12 July 2018

1 reference

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Insulin degradation by hepatocytes in primary culture

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=323688

Inhibition by bacitracin of rat adipocyte plasma membrane degradation of 125I-insulin is associated with an increase in plasma membrane bound insulin and a potentiation of glucose oxidation by adipocytes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=323688

Purification to homogeneity of an insulin-degrading enzyme from human erythrocytes

25 September 2018

1 reference

12 December 2020

Plate binding assay for monoclonal anti-receptor antibodies

1 reference

12 December 2020

Production and characterization of a monoclonal antibody to rat liver thiol: protein-disulfide oxidoreductase/glutathione-insulin transhydrogenase

1 reference

12 December 2020

The fate of insulin bound to adipocytes. Evidence for compartmentalization and processing

1 reference

12 December 2020

Studies of the properties of the insulin protease of rat liver

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12 December 2020

An evaluation of the importance of lysosomal and neutral cytosol proteases in insulin degradation by adipocytes

1 reference

12 December 2020

Purification and characterizatoion of a protease with specificity for insulin from rat muscle

1 reference

12 December 2020

Insulin degradation by human skeletal muscle

1 reference

12 December 2020

Purification and characterization of insulin-degrading enzyme from pig skeletal muscle

1 reference

12 December 2020

Peptide intermediates in the cellular metabolism of insulin

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12 December 2020

Insulinase, insulinase-inhibitors, and diabetes mellitus

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12 December 2020

Identifiers

DOI

10.1073/PNAS.83.12.4147

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9 August 2017

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9 August 2017

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