(Q35615629)

9 August 2017

1 reference

title

Are SOCS suppressors, regulators, and degraders? (English)

1 reference

9 August 2017

James A Johnston

1

1 reference

9 August 2017

23 December 2003

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Journal of Leukocyte Biology

9 August 2017

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9 August 2017

75

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9 August 2017

743-748

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9 August 2017

5

1 reference

Structure and function of a new STAT-induced STAT inhibitor

9 August 2017

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Twenty proteins containing a C-terminal SOCS box form five structural classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

The SOCS box: a tale of destruction and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

The cytokine-inducible Scr homology domain-containing protein negatively regulates signaling by promoting apoptosis in erythroid progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Pim serine/threonine kinases regulate the stability of Socs-1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

TRIM8/GERP RING finger protein interacts with SOCS-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

The suppressors of cytokine signalling (SOCS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

SOCS3 regulates the plasticity of gp130 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

SOCS3 negatively regulates IL-6 signaling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1003507

21 January 2018

Identifiers

DOI

10.1189/JLB.1003507

1 reference

9 August 2017

1 reference

PubMed ID

14694187