(Q35617863)

9 August 2017

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title

The folate receptor as a molecular target for tumor-selective radionuclide delivery (English)

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9 August 2017

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Chun-Yen Ke

1

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9 August 2017

Carla J Mathias

series ordinal

2

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9 August 2017

Mark A Green

series ordinal

3

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9 August 2017

publication date

1 November 2003

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Nuclear Medicine and Biology

9 August 2017

published in

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9 August 2017

volume

30

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9 August 2017

issue

8

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9 August 2017

page(s)

811-817

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Potocytosis: Sequestration and Transport of Small Molecules by Caveolae

9 August 2017

cites work

1 reference

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7 January 2021

The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway

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7 January 2021

Structure and function of vacuolar class of ATP-driven proton pumps

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7 January 2021

Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis

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7 January 2021

Mediated uptake of folate by a high-affinity binding protein in sublines of L1210 cells adapted to nanomolar concentrations of folate

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7 January 2021

Normal tissue reactivity of four anti-tumor monoclonal antibodies of clinical interest

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7 January 2021

Overexpression of folate binding protein in ovarian cancers.

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7 January 2021

High-affinity folate receptor in human ovary, serous ovarian adenocarcinoma, and ascites: radioligand binding mechanism, molecular size, ionic properties, hydrophobic domain, and immunoreactivity

1 reference

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7 January 2021

Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

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7 January 2021

Folate binding protein distribution in normal tissues and biological fluids from ovarian carcinoma patients as detected by the monoclonal antibodies MOv18 and MOv19.

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7 January 2021

Selective expression of folate receptor beta and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis

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7 January 2021

Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells

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7 January 2021

A high-affinity soluble folate receptor in fluids of non-neoplastic ovarian cysts: radioligand binding, molecular size, hydrophobic residue, and immunological properties.

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7 January 2021

A step further in understanding the biology of the folate receptor in ovarian carcinoma.

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7 January 2021

Complete mapping of divergent amino acids responsible for differential ligand binding of folate receptors alpha and beta

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7 January 2021

Folate receptor type gamma is primarily a secretory protein due to lack of an efficient signal for glycosylphosphatidylinositol modification: protein characterization and cell type specificity

1 reference

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7 January 2021

Identification of amino acid residues that determine the differential ligand specificities of folate receptors alpha and beta

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7 January 2021

Structure and regulation of a polymorphic gene encoding folate receptor type gamma/gamma'.

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7 January 2021

High-affinity folate binding in human choroid plexus. Characterization of radioligand binding, immunoreactivity, molecular heterogeneity and hydrophobic domain of the binding protein

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7 January 2021

The folate receptor in central nervous system malignancies of childhood

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7 January 2021

Ligand binding characteristics and aggregation behavior of purified cow's milk folate binding protein depends on the presence of amphiphatic substances including cholesterol, phospholipids, and synthetic detergents

1 reference

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7 January 2021

A combination of cation exchange and ligand-affinity chromatography for purification of two molecular species of the folate binding protein in human milk, one equipped with a hydrophobic glycosyl phosphatidylinositol tail: characterization of hydrop

1 reference

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7 January 2021

Ligand binding characteristics of two molecular forms, one equipped with a hydrophobic glycosyl phosphatidylinositol tail, of the folate binding protein purified from human milk

1 reference

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7 January 2021

Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells

1 reference

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7 January 2021

Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates

1 reference

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7 January 2021

Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae

1 reference

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7 January 2021

Folic acid targeting of protein conjugates into ascites tumour cells from ovarian cancer patients

1 reference

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7 January 2021

Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells

1 reference

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7 January 2021

Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro

1 reference

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7 January 2021

Selective targeting of malignant cells with cytotoxin-folate conjugates

1 reference

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7 January 2021

Folate-mediated targeting of antisense oligodeoxynucleotides to ovarian cancer cells

1 reference

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7 January 2021

Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug

1 reference

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7 January 2021

Development of a tumor-targeting MR contrast agent using the high-affinity folate receptor: work in progress

1 reference

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7 January 2021

Synthesis, purification, and tumor cell uptake of 67Ga-deferoxamine--folate, a potential radiopharmaceutical for tumor imaging

1 reference

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7 January 2021

Receptor-mediated targeting of 67Ga-deferoxamine-folate to folate-receptor-positive human KB tumor xenografts

1 reference

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7 January 2021

Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals

1 reference

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7 January 2021

Design and synthesis of [111In]DTPA-folate for use as a tumor-targeted radiopharmaceutical

1 reference

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7 January 2021

Synthesis of [(99m)Tc]DTPA-folate and its evaluation as a folate-receptor-targeted radiopharmaceutical

1 reference

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7 January 2021

Synthesis and evaluation of 99mTc(CO)(3)-DTPA-folate as a folate-receptor-targeted radiopharmaceutical

1 reference

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7 January 2021

Synthesis and biological evaluation of EC20: a new folate-derived, (99m)Tc-based radiopharmaceutical

1 reference

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7 January 2021

Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900117-3

7 January 2021

Further observations on the folate-binding factor in some leukemic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900117-3

7 January 2021

Receptor-mediated folate accumulation is regulated by the cellular folate content

1 reference

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7 January 2021

Radioimmunoscintigraphy in patients with ovarian cancer

1 reference

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7 January 2021

Influence of the route of administration on targeting of ovarian cancer with the chimeric monoclonal antibody MOv18: i.v. vs. i.p.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900117-3

7 January 2021

Radioimmunoscintigraphy of ovarian cancer with the MOv18 monoclonal antibody

1 reference

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7 January 2021

The NIH Consensus Conference on Ovarian Cancer: screening, treatment, and follow-up

1 reference

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7 January 2021

Expression of folate binding protein as a prognostic factor for response to platinum-containing chemotherapy and survival in human ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900117-3

7 January 2021

A kit formulation for preparation of [(111)In]In-DTPA-folate, a folate-receptor-targeted radiopharmaceutical

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2803%2900117-3

7 January 2021

10.1016/S0969-8051(03)00117-3

Identifiers

DOI

1 reference

9 August 2017

1 reference