(Q35620170)

English

Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant

scientific article published on 12 May 2015

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

phosphorylation

1 reference

based on heuristic

inferred from title

dengue virus protein NS2A

1 reference

based on heuristic

inferred from abstract

dengue virus protein NS4A

1 reference

based on heuristic

inferred from abstract

dengue virus protein NS4B

1 reference

based on heuristic

inferred from abstract

modulation by virus of host process

0 references

author name string

Nadine A Dalrymple

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Velasco Cimica

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Erich R Mackow

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

12 May 2015

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

e00553-15

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dengue vaccine development: strategies and challenges

1 reference

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The human CD8+ T cell responses induced by a live attenuated tetravalent dengue vaccine are directed against highly conserved epitopes

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Dengue: challenges for policy makers and vaccine developers

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An innate immunity-regulating virulence determinant is uniquely encoded by the Andes virus nucleocapsid protein

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Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response.

1 reference

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Hantavirus GnT elements mediate TRAF3 binding and inhibit RIG-I/TBK1-directed beta interferon transcription by blocking IRF3 phosphorylation

1 reference

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Innate immune sensing of flaviviruses

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The roles of IRF-3 and IRF-7 in innate antiviral immunity against dengue virus

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Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways

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Structure and ubiquitination-dependent activation of TANK-binding kinase 1.

1 reference

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Crystal structure and mechanism of activation of TANK-binding kinase 1

1 reference

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Membrane Topology and Function of Dengue Virus NS2A Protein

1 reference

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Recent insights into the complexity of Tank-binding kinase 1 signaling networks: the emerging role of cellular localization in the activation and substrate specificity of TBK1.

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An N-terminal amphipathic helix in dengue virus nonstructural protein 4A mediates oligomerization and is essential for replication

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IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling

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Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions

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DENV inhibits type I IFN production in infected cells by cleaving human STING

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NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses.

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Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity

1 reference

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Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex

1 reference

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Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity

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Dengue virus targets the adaptor protein MITA to subvert host innate immunity

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Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

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Innate immunity evasion by Dengue virus

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Endothelial cells elicit immune-enhancing responses to dengue virus infection

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STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

1 reference

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Emerging role of ubiquitination in antiviral RIG-I signaling

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Functional dissection of the TBK1 molecular network

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Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β.

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Update on the global spread of dengue

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Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections

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Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation.

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Dengue/dengue haemorrhagic fever: history and current status

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Fatal dengue hemorrhagic fever in adults during a dengue epidemic in Singapore.

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25 September 2018

Identifiers

10.1128/MBIO.00553-15

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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