(Q35629581)

9 August 2017

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title

Stem cells as vehicles for orthopedic gene therapy (English)

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9 August 2017

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Gafni Y

1

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9 August 2017

Turgeman G

2

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9 August 2017

Liebergal M

3

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9 August 2017

Pelled G

4

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9 August 2017

Gazit Z

5

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9 August 2017

Gazit D

6

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9 August 2017

publication date

1 February 2004

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9 August 2017

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9 August 2017

volume

11

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9 August 2017

issue

4

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9 August 2017

page(s)

417-426

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Multilineage differentiation from human embryonic stem cell lines

9 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Aging, articular cartilage chondrocyte senescence and osteoarthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Marrow stromal cells as stem cells for nonhematopoietic tissues

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Multilineage potential of adult human mesenchymal stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Muscle-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Gene therapy: adenovirus-mediated human bone morphogenetic protein-2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Transient production of bone morphogenetic protein 2 by allogeneic transplanted transduced cells induces bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Overview of bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Mechanism for the action of bone morphogenetic proteins and regulation of their activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Novel regulators of bone formation: molecular clones and activities

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Recombinant human bone morphogenetic protein induces bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Recombinant human bone morphogenetic protein (rhBMP) induced heterotopic bone development in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

In vivo new bone formation by direct transfer of adenoviral-mediated bone morphogenetic protein-4 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Ex vivo bone morphogenetic protein-9 gene therapy using human mesenchymal stem cells induces spinal fusion in rodents

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Exogenously regulated stem cell-mediated gene therapy for bone regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Engineered human mesenchymal stem cells: a novel platform for skeletal cell mediated gene therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Retroviral marking of human bone marrow fibroblasts: in vitro expansion and localization in calvarial sites after subcutaneous transplantation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

In vivo bone formation by human bone marrow stromal cells: effect of carrier particle size and shape

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Poly(lactide-co-glycolide)/hydroxyapatite delivery of BMP-2-producing cells: a regional gene therapy approach to bone regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Human skeletal muscle cells in ex vivo gene therapy to deliver bone morphogenetic protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Comparison of multi-lineage cells from human adipose tissue and bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Bone induction by BMP-2 transduced stem cells derived from human fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Embryonic Stem Cells as Developmental Model in vitro. Preface

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Compactin enhances osteogenesis in murine embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Human embryonic stem cell research: ethical and legal issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Pluripotency of mesenchymal stem cells derived from adult marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Osteoporosis in men: a cellular endocrine perspective of an increasingly common clinical problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Estrogen modulates estrogen receptor ? and ? expression, osteogenic activity, and apoptosis in mesenchymal stem cells (MSCs) of osteoporotic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Transfer of proalpha2(I) cDNA into cells of a murine model of human Osteogenesis Imperfecta restores synthesis of type I collagen comprised of alpha1(I) and alpha2(I) heterotrimers in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Highly efficient retroviral gene transfer based on centrifugation-mediated vector preloading of tissue culture vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Use of VSV-G pseudotyped retroviral vectors to target murine osteoprogenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Human bone marrow stromal cells are efficiently transduced by vesicular stomatitis virus-pseudotyped retrovectors without affecting subsequent osteoblastic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Development of an MFG-based retroviral vector system for secretion of high levels of functionally active human BMP4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Bone-directed expression of Col1a1 promoter-driven self-inactivating retroviral vector in bone marrow cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Apoptosis and cellular vitality: issues in osteoarthritic cartilage degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Gene therapy for arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Gene mediated insulin-like growth factor-I delivery to the synovium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Regeneration of hyaline cartilage by cell-mediated gene therapy using transforming growth factor beta 1-producing fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Bone marrow stromal stem cells: nature, biology, and potential applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2 and BMP-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Wnt-3A enhances bone morphogenetic protein-2-mediated chondrogenesis of murine C3H10T1/2 mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

A light and electron microscopic study of ectopic tendon and ligament formation induced by bone morphogenetic protein-13 adenoviral gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Myoblast-mediated gene transfer to the joint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Direct-, fibroblast- and myoblast-mediated gene transfer to the anterior cruciate ligament

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Circulating skeletal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Morphologic analysis of BMP-9 gene therapy-induced osteogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Growth/Differentiation Factor-5 Induces Angiogenesisin Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Bone Morphogenetic Proteins-2, -12, and -13 Modulate in Vitro Development of Engineered Cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

Stem cells and the promise of eternal youth: embryonic versus adult stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Systemically administered rhBMP-2 promotes MSC activity and reverses bone and cartilage loss in osteopenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Recombinant human bone morphogenetic protein-2 stimulates differentiation in primary cultures of fetal rat calvarial osteoblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

BMP4-expressing muscle-derived stem cells differentiate into osteogenic lineage and improve bone healing in immunocompetent mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Clinical evaluation of recombinant human bone morphogenetic protein-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Osteoinductive molecules in orthopaedics: basic science and preclinical studies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Effect of bone morphogenetic protein-2-expressing muscle-derived cells on healing of critical-sized bone defects in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Bone loss (osteopenia) in old male mice results from diminished activity and availability of TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Rescue of the osteopetrotic defect in op/op mice by osteoblast-specific targeting of soluble colony-stimulating factor-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Insulinlike growth factor-I gene therapy applications for cartilage repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Cartilage and bone regeneration using gene-enhanced tissue engineering

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

The effects of initial end contact on medial collateral ligament healing: a morphological and biomechanical study in a rabbit model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Early medial collateral ligament scars have inferior creep behaviour

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Enhancement of tendon-bone integration of anterior cruciate ligament grafts with bone morphogenetic protein-2 gene transfer: a histological and biomechanical study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

BMP-12 gene transfer augmentation of lacerated tendon repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Bone morphogenetic protein-12 and -13 inhibit terminal differentiation of myoblasts, but do not induce their differentiation into osteoblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Systematic analysis of reportedly distinct populations of multipotent bone marrow-derived stem cells reveals a lack of distinction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Adenoviral delivery of LIM mineralization protein-1 induces new-bone formation in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302197

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302197

1 reference

9 August 2017

1 reference