(Q35629588)

9 August 2017

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title

Osteoarthritis gene therapy (English)

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9 August 2017

0 references

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Evans CH

1

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9 August 2017

Gouze JN

2

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9 August 2017

Gouze E

3

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9 August 2017

Robbins PD

4

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9 August 2017

Ghivizzani SC

5

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9 August 2017

publication date

1 February 2004

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9 August 2017

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9 August 2017

volume

11

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9 August 2017

issue

4

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9 August 2017

page(s)

379-389

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Impact of osteoarthritis on individuals and society: how much disability? Social consequences and health economic implications

9 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Potential treatment of osteoarthritis by gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Radiologic progression of hip and knee osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Crystal-induced inflammation and cartilage degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Apoptosis and cellular vitality: issues in osteoarthritic cartilage degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Roles of chondrocytes in the pathogenesis of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Matrix metalloproteinases: a tail of a frog that became a prince

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Functional and biochemical characterization of ADAMs and their predicted role in protein ectodomain shedding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Aggrecanases and cartilage matrix degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Nitric oxide and cartilage metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Activation of stress-activated protein kinase in osteoarthritic cartilage: evidence for nitric oxide dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

The role of COX-2 produced by cartilage in arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Pathophysiology of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

The role of crystals in articular tissue degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Advanced glycation endproducts and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Cartilage tissue remodeling in response to mechanical forces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Phenotypic expression of equine articular chondrocytes grown in three-dimensional cultures supplemented with supraphysiologic concentrations of insulin-like growth factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Development of gene-based therapies for cartilage repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Lessons from animal models of osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Update: treatment of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Joint irrigation as treatment for osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

A controlled trial of arthroscopic surgery for osteoarthritis of the knee

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Glucosamine and chondroitin sulfate are effective inthe management of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Anticytokine therapy for osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Gene transfer to synoviocytes: prospects for gene treatment of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Gene therapy for arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Gene therapy for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Gene therapy for rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Direct gene delivery strategies for the treatment of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

In vivo gene delivery to synovium by lentiviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Delivery of plasmid DNA to articular chondrocytes via novel collagen-glycosaminoglycan matrices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Lipofection of rabbit chondrocytes and long lasting expression of a lacZ reporter system in alginate beads

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Genetic enhancement of matrix synthesis by articular chondrocytes: comparison of different growth factor genes in the presence and absence of interleukin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Transplantation of adenovirally transduced allogeneic chondrocytes into articular cartilage defects in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Functional genomic analysis of type II IL-1beta decoy receptor: potential for gene therapy in human arthritis and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

The interleukin-1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Molecular basis for differences between human joints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

The prospect of treating rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Guidelines for the medical management of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

Guidelines for the medical management of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

The nature and causes of osteoarthrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Experimental arthritis induced by intraarticular injection of allogenic cartilaginous particles into rabbit knees

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Type II collagen degradation and its regulation in articular cartilage in osteoarthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Degradative enzymes in osteoarthritis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

The role of C-C chemokines and their receptors in osteoarthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Cartilage damaging activities of fibronectin fragments derived from cartilage and synovial fluid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Autocrine stimulation by insulin-like growth factor 1 and insulin-like growth factor 2 mediates chondrocyte survival in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Evaluation and treatment of the arthritic knee

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Operative treatment of osteoarthrosis. Current practice and future development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

The genetic contribution to radiographic hip osteoarthritis in women: results of a classic twin study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Adenovirus-mediated gene transfer of glutamine: fructose-6-phosphate amidotransferase antagonizes the effects of interleukin-1beta on rat chondrocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: a feasibility study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Autologous chondrocytes used for articular cartilage repair: an update.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor. Potential for pharmacological intervention

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Detection of interleukin-1 in the cartilage of patients with osteoarthritis: a possible autocrine/paracrine role in pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Human knee and ankle cartilage explants: catabolic differences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

The safety and efficacy of interleukin-1 receptor antagonist in the treatment of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302196

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302196

1 reference

Dimensions Publication ID

9 August 2017

1038726748

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1 reference