(Q35634933)

9 August 2017

title

Suppression of coronavirus replication by inhibition of the MEK signaling pathway (English)

1 reference

9 August 2017

1 reference

Yingyun Cai

1

1 reference

9 August 2017

Yin Liu

series ordinal

2

1 reference

9 August 2017

Xuming Zhang

series ordinal

3

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 November 2006

1 reference

9 August 2017

1 reference

9 August 2017

volume

81

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9 August 2017

issue

2

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9 August 2017

page(s)

446-456

1 reference

Induction of transcription factor Egr-1 gene expression in astrocytoma cells by Murine coronavirus infection

9 August 2017

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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SYNCRIP, a member of the heterogeneous nuclear ribonucleoprotein family, is involved in mouse hepatitis virus RNA synthesis

12 July 2018

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ERK-1/2 activity is required for efficient RSV infection

12 July 2018

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12 July 2018

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Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway

12 July 2018

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MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells

12 July 2018

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Mitochondrial aconitase binds to the 3' untranslated region of the mouse hepatitis virus genome

12 July 2018

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Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

12 July 2018

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The leader RNA of coronavirus mouse hepatitis virus contains an enhancer-like element for subgenomic mRNA transcription

12 July 2018

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

12 July 2018

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Identification of mouse hepatitis virus papain-like proteinase 2 activity

12 July 2018

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Host protein interactions with the 3' end of bovine coronavirus RNA and the requirement of the poly(A) tail for coronavirus defective genome replication

12 July 2018

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Four proteins processed from the replicase gene polyprotein of mouse hepatitis virus colocalize in the cell periphery and adjacent to sites of virion assembly.

12 July 2018

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The putative helicase of the coronavirus mouse hepatitis virus is processed from the replicase gene polyprotein and localizes in complexes that are active in viral RNA synthesis.

12 July 2018

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

12 July 2018

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Colocalization and membrane association of murine hepatitis virus gene 1 products and De novo-synthesized viral RNA in infected cells.

12 July 2018

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Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway.

12 July 2018

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Polypyrimidine tract-binding protein binds to the leader RNA of mouse hepatitis virus and serves as a regulator of viral transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein

12 July 2018

1 reference

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Mouse hepatitis virus nucleocapsid protein as a translational effector of viral mRNAs

12 July 2018

1 reference

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

12 July 2018

1 reference

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Processing of the coronavirus MHV-JHM polymerase polyprotein: identification of precursors and proteolytic products spanning 400 kilodaltons of ORF1a

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Mouse hepatitis virus 3C-like protease cleaves a 22-kilodalton protein from the open reading frame 1a polyprotein in virus-infected cells and in vitro.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Entry of mouse hepatitis virus into cells by endosomal and nonendosomal pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Mitogen-activated protein kinase pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Characterization of a second cleavage site and demonstration of activity in trans by the papain-like proteinase of the murine coronavirus mouse hepatitis virus strain A59.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Regulation of the initiation of coronavirus JHM infection in primary oligodendrocytes and L-2 fibroblasts

12 July 2018

1 reference

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Dephosphorylation of the nucleocapsid protein of inoculum JHMV may be essential for initiating replication.

12 July 2018

1 reference

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Intracellular and in vitro-translated 27-kDa proteins contain the 3C-like proteinase activity of the coronavirus MHV-A59.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Nucleocapsid-independent assembly of coronavirus-like particles by co-expression of viral envelope protein genes.

12 July 2018

1 reference

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The production of recombinant infectious DI-particles of a murine coronavirus in the absence of helper virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Transcriptional regulation by MAP kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Three different cellular proteins bind to complementary sites on the 5'-end-positive and 3'-end-negative strands of mouse hepatitis virus RNA.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Coronavirus leader RNA regulates and initiates subgenomic mRNA transcription both in trans and in cis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Requirement of the 5'-end genomic sequence as an upstream cis-acting element for coronavirus subgenomic mRNA transcription.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Interactions between the cytoplasmic proteins and the intergenic (promoter) sequence of mouse hepatitis virus RNA: correlation with the amounts of subgenomic mRNA transcribed

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

A synthetic inhibitor of the mitogen-activated protein kinase cascade

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Characterization of the leader papain-like proteinase of MHV-A59: identification of a new in vitro cleavage site

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

The virus-specific intracellular RNA species of two murine coronaviruses: MHV-A59 and MHV-JHM

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Replication and plaque formation of mouse hepatitis virus (MHV-2) in mouse cell line DBT culture.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

In vitro replication of mouse hepatitis virus strain A59

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Biosynthesis, structure, and biological activities of envelope protein gp65 of murine coronavirus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Identification of a new transcriptional initiation site and the corresponding functional gene 2b in the murine coronavirus RNA genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Coronavirus: organization, replication and expression of genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Alteration of the pH dependence of coronavirus-induced cell fusion: effect of mutations in the spike glycoprotein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Phosphoproteins of murine hepatitis viruses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Identification and Characterization of a 65-kDa Protein Processed from the Gene 1 Polyprotein of the Murine Coronavirus MHV-A59

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797436

Evolution of the 5'-end of genomic RNA of murine coronaviruses during passages in vitro

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17079328

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Further requirements for cleavage by the murine coronavirus 3C-like proteinase: identification of a cleavage site within ORF1b

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17079328

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of MKK1/2 kinase activity in human cytomegalovirus infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17079328

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.01705-06

1 reference

9 August 2017

1 reference

9 August 2017

1 reference