(Q35640925)

9 August 2017

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title

Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification (English)

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9 August 2017

endometrial carcinoma

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Sigurd F Lax

1

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9 August 2017

28 January 2004

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9 August 2017

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9 August 2017

444

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9 August 2017

213-223

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9 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s00428-003-0947-3

9 August 2017

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Minimal uterine serous carcinoma: diagnosis and clinicopathologic correlation

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12 December 2020

Comparative immunohistochemical study of endometrioid and serous papillary carcinoma of endometrium

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12 December 2020

beta- Catenin mutations and aberrant nuclear expression during endometrial tumorigenesis

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12 December 2020

Mutational analysis of MLH1 and MSH2 in 25 prospectively-acquired RER+ endometrial cancers

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12 December 2020

Mutations of the beta-catenin gene in endometrial carcinomas.

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12 December 2020

MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers

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12 December 2020

PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma

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12 December 2020

The risk of endometrial cancer in hereditary nonpolyposis colorectal cancer.

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12 December 2020

The epidemiology of endometrial cancer in hereditary nonpolyposis colorectal cancer

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12 December 2020

β- And γ-catenin expression in endometrial carcinoma. Relationship with clinicopathological features and microsatellite instability

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12 December 2020

Peripheral aromatization as a risk factor for breast and endometrial cancer in postmenopausal women: a review

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12 December 2020

Abnormalities of E- and P-cadherin and catenin (β-, γ-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia

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12 December 2020

Genetic instability of microsatellites in endometrial carcinoma

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12 December 2020

E-cadherin expression in endometrioid, papillary serous, and clear cell carcinoma of the endometrium

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12 December 2020

Chromosomal imbalances in the colorectal carcinomas with microsatellite instability

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12 December 2020

Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas.

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12 December 2020

Methylation of hMLH1 in a population-based series of endometrial carcinomas

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12 December 2020

Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study

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12 December 2020

Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair

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12 December 2020

Comparison of estrogen and progesterone receptor, Ki-67, and p53 immunoreactivity in uterine endometrioid carcinoma and endometrioid carcinoma with squamous, mucinous, secretory, and ciliated cell differentiation

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12 December 2020

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

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12 December 2020

Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization

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12 December 2020

Chromosome aberrations in solid tumors

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12 December 2020

The outcome of stage I-II clinically and surgically staged papillary serous and clear cell endometrial cancers when compared with endometrioid carcinoma

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12 December 2020

Lack of MSH2 and MSH6 characterizes endometrial but not colon carcinomas in hereditary nonpolyposis colorectal cancer

1 reference

12 December 2020

Genetic aberrations detected by comparative genomic hybridization predict outcome in patients with endometrioid carcinoma

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12 December 2020

hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

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12 December 2020

MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas

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12 December 2020

Identification of HER-2/neu oncogene amplification by fluorescence in situ hybridization in stage I endometrial carcinoma.

1 reference

12 December 2020

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

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12 December 2020

K-ras point mutations in endometrial carcinoma: effect on outcome is dependent on age of patient

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12 December 2020

BAX somatic frameshift mutations in endometrioid adenocarcinomas of the endometrium: evidence for a tumor progression role in endometrial carcinomas with microsatellite instability

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12 December 2020

Risk of Endometrial Cancer Following Estrogen Replacement With and Without Progestins

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12 December 2020

Amplification and overexpression of HER-2/neu (c-erbB2) in endometrial cancers: correlation with overall survival

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12 December 2020

Mutations of the Ki-ras oncogene in carcinoma of the endometrium.

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12 December 2020

Distinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumorigenesis

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12 December 2020

p53 expression as a prognostic indicator of 5-year survival in endometrial cancer

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12 December 2020

Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients

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12 December 2020

The role of p16-cyclin d/CDK-pRb pathway in the tumorigenesis of endometrioid-type endometrial carcinoma

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12 December 2020

Microarray analysis reveals distinct gene expression profiles among different histologic types of endometrial cancer.

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12 December 2020

Clear cell carcinoma of the endometrium is characterized by a distinctive profile of p53, Ki-67, estrogen, and progesterone receptor expression.

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12 December 2020

Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas

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12 December 2020

MLH1 and MSH2 protein expression as a pre-screening marker in hereditary and non-hereditary endometrial hyperplasia and cancer

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12 December 2020

p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.

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12 December 2020

Clonal analysis and mutations in the PTEN and the K-ras genes in endometrial hyperplasia

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12 December 2020

Pten, a protean tumor suppressor

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12 December 2020

PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics.

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12 December 2020

P16/MTS1 and pRB expression in endometrial carcinomas

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12 December 2020

Causes and consequences of microsatellite instability in endometrial carcinoma.

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12 December 2020

Molecular evidence that most but not all carcinosarcomas of the uterus are combination tumors

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12 December 2020

Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies

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12 December 2020

K-ras exon 2 point mutations in human endometrial cancer.

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12 December 2020

p53 gene mutations in human endometrial carcinoma

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12 December 2020

Distinct PTEN mutational spectra in hereditary non-polyposis colon cancer syndrome-related endometrial carcinomas compared to sporadic microsatellite unstable tumors.

1 reference

12 December 2020

Loss of heterozygosity of the retinoblastoma gene is correlated with the altered pRb expression in human endometrial cancer.

1 reference

12 December 2020

HER-2/neu amplification and overexpression in endometrial carcinoma.

1 reference

12 December 2020

Endometrial carcinoma: the prognostic impact of papillary serous carcinoma (UPSC) in relation to nuclear grade, DNA ploidy and p53 expression

1 reference

12 December 2020

A genetic model for colorectal tumorigenesis

1 reference

12 December 2020

Anticorresponding mutations of the KRAS and PTEN genes in human endometrial cancer

1 reference

12 December 2020

Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized morphometry

1 reference

12 December 2020

Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas

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12 December 2020

Lessons from hereditary colorectal cancer

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12 December 2020

Favorable survival associated with microsatellite instability in endometrioid endometrial cancers

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12 December 2020

Case-control study of endogenous steroid hormones and endometrial cancer

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12 December 2020

Two pathogenetic types of endometrial carcinoma

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12 December 2020

Clinical Findings with Implications for Genetic Testing in Families with Clustering of Colorectal Cancer

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12 December 2020

Mutation and allelic loss of the p53 gene in endometrial carcinoma. Incidence and outcome in 92 surgical patients

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12 December 2020

Microsatellite instability in endometrial carcinomas: clinicopathologic correlations in a series of 42 cases

1 reference

12 December 2020

Altered expression of hMLH1 and hMSH2 protein in endometrial carcinomas with microsatellite instability

1 reference

12 December 2020

Genetic instability in colorectal cancers

1 reference

12 December 2020

Beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtype.

1 reference

12 December 2020

The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways

1 reference

12 December 2020

Frequent hypermethylation of MLH1 promoter in normal endometrium of patients with endometrial cancers

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12 December 2020

Genetic imbalances in precursor lesions of endometrial cancer detected by comparative genomic hybridization

1 reference

12 December 2020

Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma

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12 December 2020

Microsatellite instability is uncommon in uterine serous carcinoma

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12 December 2020

Expression of EGFR, HER-2/neu, P53, and PCNA in endometrioid, serous papillary, and clear cell endometrial adenocarcinomas

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12 December 2020

Endometrial intraepithelial carcinoma: a distinctive lesion specifically associated with tumors displaying serous differentiation

1 reference

12 December 2020

Direct sequencing of the p53 gene shows absence of mutations in endometrioid endometrial adenocarcinomas expressing p53 protein

1 reference

12 December 2020

Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome.

1 reference

12 December 2020

Hypermethylation in promoter region of E-cadherin gene is associated with tumor dedifferention and myometrial invasion in endometrial carcinoma

1 reference

12 December 2020

Hereditary aspects of endometrial adenocarcinoma

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12 December 2020

Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: associations with family history and histopathology

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12 December 2020

Clear cell carcinoma of the endometrium. Prognosis and metastatic pattern

1 reference

12 December 2020

Risk factors and hormone levels in patients with serous and endometrioid uterine carcinomas.

1 reference

12 December 2020

Multivariable analysis of DNA ploidy, p53, and HER-2/neu as prognostic factors in endometrial cancer

1 reference

12 December 2020

Microsatellite instability in endometrial carcinoma

1 reference

12 December 2020

Alteration of p16 and p15 genes in human uterine tumours

1 reference

12 December 2020

Cancer risk in young women at risk of hereditary nonpolyposis colorectal cancer: implications for gynecologic surveillance.

1 reference

12 December 2020

K-ras activation in neoplasms of the human female reproductive tract

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12 December 2020

A dualistic model for endometrial carcinogenesis based on immunohistochemical and molecular genetic analyses.

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12 December 2020

Endometrial intraepithelial carcinoma with associated peritoneal carcinomatosis

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12 December 2020

Molecular pathology of endometrial hyperplasia and carcinoma

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12 December 2020

Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers

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12 December 2020

Comparison of benign and malignant endometrial lesions for their p53 state, using immunohistochemistry and temperature-gradient gel electrophoresis

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12 December 2020

p53 in endometrial cancer and its putative precursors: evidence for diverse pathways of tumorigenesis

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12 December 2020

Genomics and proteomics in cancer

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12 December 2020

Fluorescence in situ hybridization analysis of HER-2/neu, c-myc, and p53 in endometrial cancer

1 reference

12 December 2020

Microsatellite instability: the mutator that mutates the other mutator

1 reference

12 December 2020

Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma

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12 December 2020

PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma

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12 December 2020

DCC genetic alterations and expression in endometrial carcinoma

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12 December 2020

Cancer risk in mutation carriers of DNA-mismatch-repair genes

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12 December 2020

Immunohistochemical analysis of the expression of cdk4 and p16INK4 in human endometrioid-type endometrial carcinoma

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12 December 2020

Correlation of proliferation indices, apoptosis, and related oncogene expression (bcl-2 and c-erbB-2) and p53 in proliferative, hyperplastic, and malignant endometrium

1 reference

12 December 2020

Loss of nuclear p16 protein expression is not associated with promoter methylation but defines a subgroup of aggressive endometrial carcinomas with poor prognosis.

1 reference

12 December 2020

10.1007/S00428-003-0947-3

Identifiers

DOI

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9 August 2017

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PubMed ID

14747944