(Q35643695)

English

CUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling.

scientific article published on 14 November 2011

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scholarly article

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16 January 2020

CUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling (English)

1 reference

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16 January 2020

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16 January 2020

author name string

Wei-Na Zhang

1

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16 January 2020

Li Wang

2

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16 January 2020

Qiong Wang

3

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16 January 2020

Xue Luo

4

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16 January 2020

Di-Feng Fang

5

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16 January 2020

Yuan Chen

6

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16 January 2020

Jiang-Hong Man

8

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16 January 2020

Qing Xia

9

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16 January 2020

Bao-Feng Jin

10

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16 January 2020

Wei-Hua Li

11

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16 January 2020

Tao Li

12

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16 January 2020

Bing Liang

13

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16 January 2020

Liang Chen

14

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16 January 2020

Wei-Li Gong

15

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16 January 2020

Ming Yu

16

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16 January 2020

Ai-Ling Li

17

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16 January 2020

Tao Zhou

18

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16 January 2020

Hui-Yan Li

19

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16 January 2020

language of work or name

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publication date

14 November 2011

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16 January 2020

Journal of Biological Chemistry

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16 January 2020

287

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16 January 2020

1

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16 January 2020

382-392

1 reference

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16 January 2020

Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

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STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

1 reference

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Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors

1 reference

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Green tea catechins inhibit angiogenesis through suppression of STAT3 activation

1 reference

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27 July 2018

Crif1 is a novel transcriptional coactivator of STAT3

1 reference

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27 July 2018

Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

1 reference

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27 July 2018

Constitutive suppressor of cytokine signaling 3 expression confers a growth advantage to a human melanoma cell line.

1 reference

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27 July 2018

CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Regulation of STAT3-mediated signaling by LMW-DSP2

1 reference

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27 July 2018

Physical and functional interactions between Daxx and STAT3

1 reference

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The STATs of cancer--new molecular targets come of age

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

The SOCS box: a tale of destruction and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

What does Stat3 do?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Stat proteins and oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Negative regulation of cytokine signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

SOCS: physiological suppressors of cytokine signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

STATs in oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249090

27 July 2018

Stat3 as an oncogene

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27 July 2018

Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling

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27 July 2018

Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

1 reference

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27 July 2018

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

1 reference

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27 July 2018

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

1 reference

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27 July 2018

Twenty proteins containing a C-terminal SOCS box form five structural classes

1 reference

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27 July 2018

Specific inhibition of Stat3 signal transduction by PIAS3

1 reference

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27 July 2018

Structure and function of a new STAT-induced STAT inhibitor

1 reference

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27 July 2018

A new protein containing an SH2 domain that inhibits JAK kinases

1 reference

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27 July 2018

CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation

1 reference

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27 July 2018

Cytokine signal transduction

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RNA polymerase II transcription factor SIII. I. Identification, purification, and properties

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

1 reference

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1 reference

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27 July 2018

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

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25 September 2018

Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1.

1 reference

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25 September 2018

Stats: transcriptional control and biological impact

1 reference

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25 September 2018

A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor

1 reference

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25 September 2018

Inhibition of transcription elongation by the VHL tumor suppressor protein

1 reference

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25 September 2018

What does Stat3 do?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.276832

21 January 2018

CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22084247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22084247

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.276832

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084247%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084247%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084247%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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