(Q35648144)

9 August 2017

title

Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice (English)

1 reference

9 August 2017

1 reference

Inuk Zandvakili

1

1 reference

9 August 2017

Ashley Kuenzi Davis

series ordinal

2

1 reference

9 August 2017

Guodong Hu

series ordinal

3

1 reference

9 August 2017

Yi Zheng

series ordinal

4

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 June 2015

1 reference

9 August 2017

1 reference

9 August 2017

volume

10

1 reference

9 August 2017

issue

6

1 reference

9 August 2017

page(s)

e0127923

1 reference

Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

1 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4452309/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma

27 July 2018

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RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors

27 July 2018

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27 July 2018

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The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms

27 July 2018

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Essential role of B-Raf in ERK activation during extraembryonic development

27 July 2018

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27 July 2018

1 reference

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K-ras activation generates an inflammatory response in lung tumors

27 July 2018

1 reference

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27 July 2018

1 reference

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RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis

27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

RHO-GTPases and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Tumorigenic activity of rho genes from Aplysia californica

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Critical role of Rho in cell transformation by oncogenic Ras.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

An essential role for Rac in Ras transformation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Characterization and expression of the human rhoH12 gene product

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

The a"MAZE"ing world of lung-specific transgenic mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Loss of RhoB expression promotes migration and invasion of human bronchial cells via activation of AKT1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

A global double-fluorescent Cre reporter mouse

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Overexpression of RhoA is associated with poor prognosis in hepatocellular carcinoma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Expression of seven main Rho family members in gastric carcinoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

Rho GTPases are over-expressed in human tumors.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

A role for Rho in Ras transformation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4452309

RhoA protein expression in primary breast cancers and matched lymphocytes is associated with progression of the disease

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26030593

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Correlation between RhoA overexpression and tumour progression in esophageal squamous cell carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26030593

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0127923

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference