(Q35653961)

9 August 2017

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title

Clinical pharmacokinetics of metronidazole and other nitroimidazole anti-infectives (English)

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9 August 2017

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Lau AH

1

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9 August 2017

Lam NP

2

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9 August 2017

Piscitelli SC

3

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9 August 2017

Wilkes L

4

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9 August 2017

Danziger LH

5

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9 August 2017

language of work or name

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1 November 1992

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Clinical Pharmacokinetics

9 August 2017

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9 August 2017

23

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9 August 2017

328-364

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9 August 2017

5

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https://scigraph.springernature.com/pub.10.2165/00003088-199223050-00002

9 August 2017

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cites work

Multiple-dose kinetics of the trypanosomicide benznidazole in man

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12 December 2020

Possible interaction between ethanol and vaginally administered metronidazole

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12 December 2020

Metronidazole Treatment in Pregnancy

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12 December 2020

Pharmacokinetics of metronidazole in patients undergoing peritoneal dialysis

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12 December 2020

Metronidazole elimination is preserved in the elderly

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12 December 2020

Disposition and metabolism of metronidazole in patients with liver failure

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12 December 2020

The stereoselective interaction of warfarin and metronidazole in man

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12 December 2020

Misonidazole neuropathy A prospective study

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12 December 2020

In vitro activity of the two principal oxidative metabolites of metronidazole against Bacteroides fragilis and related species

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12 December 2020

The neurotoxicity of misonidazole: pooling of data from five centres

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12 December 2020

Pharmacokinetics of ornidazole in patients with acute viral hepatitis, alcoholic cirrhosis, and extrahepatic cholestasis

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12 December 2020

Pseudomembranous colitis after treatment with metronidazole

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12 December 2020

Pharmacokinetics of ornidazole in patients with severe liver cirrhosis

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12 December 2020

Disposition and removal of metronidazole in patients undergoing haemodialysis

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12 December 2020

Pharmacokinetics of metronidazole in severely malnourished and nutritionally rehabilitated children

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12 December 2020

Ornidazole in the treatment of active Crohn's disease

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12 December 2020

Short time prophylaxis with ornidazole in elective colo-rectal surgery

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12 December 2020

Central nervous system toxicity associated with metronidazole therapy

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12 December 2020

Antitrichomonad action, mutagenicity, and reduction of metronidazole and other nitroimidazoles

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12 December 2020

Penetration of the blood brain barrier by metronidazole and tinidazole.

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12 December 2020

Metronidazole pharmacokinetics in patients with hepatic encephalopathy

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12 December 2020

Some new nitroimidazole derivatives. Clinical trials in amebic liver abscess

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12 December 2020

Metronidazole-spiramycin combination. In situ concentrations and synergism compared with the minimal inhibitory concentration of the buccal flora

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12 December 2020

Antipyrine and metronidazole metabolism during occupational exposure to gasoline

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12 December 2020

A significant interaction between metronidazole and warfarin

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12 December 2020

Pharmacokinetics and metabolism of 14C-tinidazole in humans

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12 December 2020

Metronidazole and anaerobic sepsis

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12 December 2020

Kinetics of misonidazole enantiomers

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12 December 2020

The pharmacokinetics of metronidazole and its metabolites in critically ill patients

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12 December 2020

Tinidazole and metronidazole pharmocokinetics in man and mouse

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12 December 2020

Lack of inhibitory effect of metronidazole on theophylline disposition in healthy subjects

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12 December 2020

Bioavailability of metronidazole in fasting and non-fasting healthy subjects and in patients with Crohn's disease

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12 December 2020

Metronidazole kinetics and bioavailability in patients undergoing gastrointestinal surgery

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12 December 2020

Metronidazole-induced pancreatitis

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12 December 2020

Bioassay of Metronidazole with Either Anaerobic or Aerobic Incubation

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12 December 2020

Placental transfer of metronidazole in the first trimester of pregnancy

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12 December 2020

Disposition of oral metronidazole in hepatic cirrhosis and in hepatosplenic schistosomiasis

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12 December 2020

The effect of dietary energy and protein deficiency on drug metabolism

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12 December 2020

Serum concentrations of metronidazole and its main metabolite in patients with active Crohn's disease: correlation with disease activity and therapeutic efficacy?

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12 December 2020

Possible alteration of metronidazole metabolism by phenobarbital

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12 December 2020

Interaction between cimetidine and metronidazole

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12 December 2020

Colitis associated with metronidazole therapy

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12 December 2020

Single-dose pharmacokinetics of the trypanosomicide benznidazole in man

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12 December 2020

Clinical chemosensitization by misonidazole and related compounds: a critical evaluation

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12 December 2020

Pharmacokinetics and tissue distribution of metronidazole in the new born infant

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12 December 2020

Metronidazole Impairs Clearance of Phenytoin but Not of Alprazolam or Lorazepam

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12 December 2020

Pharmacokinetics of tinidazole in chronic renal failure and in patients on haemodialysis

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12 December 2020

Microbiological agar diffusion assay for metronidazole concentrations in serum

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12 December 2020

Impaired elimination of metronidazole in decompensated chronic liver disease

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12 December 2020

Determination of therapeutic levels of metronidazole in plasma by gas-liquid chromatography

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12 December 2020

Pharmacokinetics of metronidazole and its major metabolite after a high intravenous dose

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12 December 2020

Suspected metronidazole hepatotoxicity

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12 December 2020

Treatment with metronidazole of three patients with serious infections due to Bacteroides fragilis

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12 December 2020

Metronidazole clearance: A one-sample method and influencing factors

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12 December 2020

Disulfiram-Induced Encephalopathy

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12 December 2020

No significant effect of metoclopramide on misonidazole elimination in man.

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12 December 2020

The pharmacokinetics of a single intravenous dose of metronidazole in pregnant patients

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12 December 2020

Assay of metronidazole by HPLC compared with microbial method

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12 December 2020

Comparative pharmacokinetics of metronidazole and tinidazole as influenced by administration route

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12 December 2020

Human pharmacokinetics and toxicity of high-dose metronidazole administered orally and intravenously.

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12 December 2020

In vivo potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea by the radiation sensitizer benznidazole

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12 December 2020

Impaired elimination of metronidazole in decompensated chronic liver disease

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12 December 2020

Effect of the preparation trichomonacid on pregnancy in experimental animals

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12 December 2020

Comparative pharmacokinetics of metronidazole and tinidazole and their tissue penetration

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12 December 2020

Absorptiometric, Polarographic, and Gas Chromatographic Assays for the Determination of N-1-substituted Nitroimidazoles in Blood and Urine

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12 December 2020

Comparative Pharmacokinetic Studies of Ornidazole and Metronidazole in Man

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12 December 2020

Lack of evidence for cancer due to use of metronidazole

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12 December 2020

Metronidazole: pharmacokinetic observations in severely ill patients

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12 December 2020

Twelve-hourly dosage schedule for oral and intravenous metronidazole

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12 December 2020

Metabolic Studies of Ornidazole in the Rat, in the Dog and in Man

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12 December 2020

Metronidazole kinetics in dialysis patients

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12 December 2020

No significant effect of cimetidine on the pharmacokinetics of misonidazole in man

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12 December 2020

Pharmacokinetics of tinidazole in male and female subjects

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12 December 2020

The metabolism of tinidazole in the rat and dog

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12 December 2020

Pharmacokinetics and bioavailability of metronidazole after tablets, suppositories and intravenous administration

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12 December 2020

Metabolic interactions of ciprofloxacin

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12 December 2020

Determination of metronidazole and its two major metabolites in biological fluids by high pressure liquid chromatography

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12 December 2020

Metronidazole in breast milk

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12 December 2020

Pharmacokinetics of metronidazole as determined by bioassay

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12 December 2020

Interaction between metronidazole and drugs eliminated by oxidative metabolism.

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12 December 2020

Acute organic brain syndrome: a complication of disulfiram therapy.

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12 December 2020

Steady-state pharmacokinetics of metronidazole in Crohn's disease

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12 December 2020

Misonidazole in patients receiving radical radiotherapy: pharmacokinetic effects of phenytoin, tumor response and neurotoxicity

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12 December 2020

Effect of tinidazole prophylaxis on the normal microflora in patients undergoing colorectal surgery.

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12 December 2020

Disposition of metronidazole and its effects on sulphasalazine metabolism in patients with inflammatory bowel disease

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12 December 2020

Comparison of the pharmacokinetics of metronidazole in healthy female volunteers following either a single oral or intravenous dose

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12 December 2020

Treatment of giardiasis: comparative evaluation of ornidazole and tinidazole as a single oral dose

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12 December 2020

Systemic absorption of metronidazole by the vaginal route

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12 December 2020

Systemic concentrations of metronidazole and its main metabolites after intravenous oral and vaginal administration

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12 December 2020

The neurotoxicity of misonidazole: potential modifying role of phenytoin sodium and dexamethasone

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12 December 2020

High-dose metronidazole: pharmacokinetics and bioavailability using an iv preparation and application of its use as a radiosensitizer.

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12 December 2020

Haemolytic-uraemic syndrome after treatment with metronidazole

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12 December 2020

Pharmacokinetics of metronidazole in patients undergoing continuous ambulatory peritoneal dialysis

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12 December 2020

Colorimetric Determination of Some N-1-Substituted Nitroimidazoles

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12 December 2020

Induction of lung tumors and malignant lymphomas in mice by metronidazole

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12 December 2020

Trichomoniasis and metronidazole

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12 December 2020

Pharmacokinetics of intravenous metronidazole at different dosages in healthy subjects

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12 December 2020

An evaluation of metronidazole in the prophylaxis and treatment of anaerobic infections in surgical patients

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12 December 2020

Preclinical pharmacokinetics of benznidazole

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12 December 2020

Concentration of Metronidazole in Serum during Peritoneal Dialysis

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12 December 2020

Pharmacokinetics of tinidazole and metronidazole in women after single large oral doses

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12 December 2020

Pharmacokinetics of intravenous metronidazole in neonates

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12 December 2020

Disposition kinetics of metronidazole in children

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12 December 2020

Metronidazole kinetics in patients with acute renal failure on dialysis: a cumulative study

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12 December 2020

Sensitive high-performance liquid chromatographic method for the determination of metronidazole and metabolites

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12 December 2020

Pharmacokinetics and tissue penetration of a single dose of ornidazole (1,000 milligrams intravenously) for antibiotic prophylaxis in colorectal surgery

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12 December 2020

Metronidazole-associated pancreatitis.

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12 December 2020

The pharmacokinetics, metabolism and tissue distribution of tinidazole

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12 December 2020

Further observations on metronidazole (Flagyl).

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12 December 2020

Disulfiram (Antabuse) Psychosis

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12 December 2020

Pharmacokinetics of ornidazole in patients with renal insufficiency; influence of haemodialysis and peritoneal dialysis

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12 December 2020

Pharmacokinetics of hypoxic cell radiosensitizers: a review.

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12 December 2020

Absorption and Excretion of Metronidazole. Part I: Serum Concentration and Urinary Excretion after Oral Administration

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12 December 2020

Difference of effective antitrypanosomal dosages of benznidazole in mice and man. Chemotherapeutic and pharmacokinetic results

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12 December 2020

Hemodialysis clearance of metronidazole and its metabolites

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12 December 2020

Pharmacokinetics of metronidazole in patients with varying degrees of renal failure

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12 December 2020

Disulfiram-like reaction associated with intravenous trimethoprim-sulfamethoxazole and metronidazole

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12 December 2020

Liquid chromatographic assay for metronidazole and tinidazole: pharmacokinetic and metabolic studies in human subjects

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12 December 2020

Effect of metronidazole on theophylline pharmacokinetics

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12 December 2020

Tinidazole pharmacokinetics in severe renal failure

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12 December 2020

Pharmacokinetic and Metabolic Studies of the Hypoxic Cell Radiosensitizer Misonidazole

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12 December 2020

Neutropenia associated with metronidazole.

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12 December 2020

Rapid determination of metronidazole in human serum and urine using a normal-phase high-performance liquid chromatographic column with aqueous solvents

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12 December 2020

Neutropenia associated with metronidazole therapy

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12 December 2020

Metabolic drug interactions--a critical review

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12 December 2020

The mechanism of alcohol intolerance produced by various therapeutic agents.

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12 December 2020

Interaction of metronidazole with phenobarbital, cimetidine, prednisone, and sulfasalazine in Crohn's disease

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12 December 2020

Neurologic Toxicity Associated with High-Dose Metronidazole Therapy

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12 December 2020

Tinidazole, a potent new antiprotozoal agent

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12 December 2020

Use of metronidazole in the treatment of trichomoniasis

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12 December 2020

Influence of dose and route of administration on disposition of metronidazole and its major metabolites

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12 December 2020

Lack of effect of cimetidine on the pharmacokinetics and metabolism of a single oral dose of metronidazole

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12 December 2020

Radiation Therapy Oncology Group clinical trials with misonidazole

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12 December 2020

Activity of metronidazole and its hydroxy and acid metabolites against clinical isolates of anaerobic bacteria

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12 December 2020

The pharmacokinetics of metronidazole and tinidazole in man

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12 December 2020

Bile and serum levels of tinidazole after a single oral dose

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12 December 2020

Interaction between alcohol and metronidazole

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12 December 2020

Age-associated pharmacokinetic changes of metronidazole

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12 December 2020

Pharmacokinetics of Metronidazole in pregnant women

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12 December 2020

Pharmacokinetics of ornidazole in neonates and infants after a single intravenous infusion

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12 December 2020

'Alcohol-antabuse' syndrome in patients receiving metronidazole during gynaecological treatment.

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12 December 2020

The pharmacokinetics of intravenous tinidazole in man

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12 December 2020

Characterization of metronidazole metabolism by human liver microsomes

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12 December 2020

Single dose prophylaxis with metronidazole in infants during abdominal surgery: a pharmacokinetic study

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12 December 2020

Pharmacokinetics of metronidazole in patients with alcoholic liver disease

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12 December 2020

Metronidazole-induced pancreatitis

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12 December 2020

Effects of phenytoin, phenobarbital, and ascorbic acid on misonidazole elimination

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12 December 2020

Use of High-Pressure Liquid Chromatography to Determine Plasma Levels of Metronidazole and Metabolites After Intravenous Administration

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12 December 2020

Pharmacokinetics of metronidazole in patients with enteric disease compared to normal volunteers

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12 December 2020

Pharmacokinetics of metronidazole and its metabolites in reduced renal function

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12 December 2020

Optimized liquid-chromatographic determination of metronidazole and its metabolites in plasma

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12 December 2020

Phenobarbital and metabolism of metronidazole

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12 December 2020

Possible nephrotoxic interaction of lithium and metronidazole

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12 December 2020

Pharmacokinetics and therapeutic efficacy of metronidazole at different dosages

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12 December 2020

Therapy for Infections Due to Anaerobic Bacteria: An Overview

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12 December 2020

Metronidazole-induced gynecomastia

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12 December 2020

Mental confusion in a patient treated with metronidazole--a concentration-related effect?

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12 December 2020

Pharmacokinetics of metronidazole in hospitalized patients

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12 December 2020

Studies on antiprotozoans. 3. Isolation, identification and quantitative determination in humans of the metabolites of a new trichomonacidal agent

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12 December 2020

Pharmacokinetics of metronidazole in healthy adult volunteers after tablets and suppositories

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12 December 2020

Single- and multiple-dose metronidazole kinetics

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12 December 2020

Metronidazole pharmacokinetics in patients with acute renal failure

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12 December 2020

Convulsions associated with high cumulative doses of metronidazole

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12 December 2020

Toxicity of Disulfiram Combined with Metronidazole

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12 December 2020

A comparative investigation of nimorazole and misonidazole as hypoxic radiosensitizers in a C3H mammary carcinoma in vivo

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12 December 2020

Increased incidence of experimental colon cancer associated with long-term metronidazole therapy.

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12 December 2020

In vitro susceptibility of anaerobic bacteria to nitroimidazoles

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12 December 2020

Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy

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12 December 2020

UROGENITAL TRICHOMONIASIS; TREATMENT WITH METRONIDAZOLE IN 2002 INCARCERATED WOMEN

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12 December 2020

Studies of the pharmacokinetic properties of nimorazole

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12 December 2020

Tinidazole in anaerobic infections: a review of its antibacterial activity, pharmacological properties and therapeutic efficacy

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12 December 2020

Treatment of vaginal trichomoniasis with a new anti-protozoal compound ( -chloromethyl-2-methyl-5-nitro-1-imidazole-ethanol)

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12 December 2020

10.2165/00003088-199223050-00002

Identifiers

DOI

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Dimensions Publication ID

9 August 2017

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