(Q35665931)

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Hidden aberrations diagnosed by interphase fluorescence in situ hybridisation and spectral karyotyping in childhood acute lymphoblastic leukaemia

scientific article published on December 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

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Europe PubMed Central

Hidden aberrations diagnosed by interphase fluorescence in situ hybridisation and spectral karyotyping in childhood acute lymphoblastic leukaemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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Ann Nordgren

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Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

1 December 2003

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Europe PubMed Central

PubMed publication ID

9 August 2017

Leukemia & Lymphoma

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Europe PubMed Central

PubMed publication ID

9 August 2017

44

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Europe PubMed Central

PubMed publication ID

9 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2039-2053

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Europe PubMed Central

PubMed publication ID

9 August 2017

Biology and clinical significance of the TEL/AML1 rearrangement

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Molecular genetics, natural history and the demise of childhood leukaemia

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Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping

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It's ALL in the diagnosis.

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Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

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High resolution detection of DNA–RNA hybrids in situ by indirect immunofluorescence

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Karyotyping human chromosomes by combinatorial multi-fluor FISH.

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Multicolor Spectral Karyotyping of Human Chromosomes

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Clinical and biologic features predict poor prognosis in acute lymphoid leukemias in children and adolescents: a Pediatric Oncology Group review

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Lymphomatous presentation of childhood acute lymphoblastic leukemia. A subgroup at high risk of early treatment failure

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Cytogenetics and molecular genetics of childhood leukemia

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Limitations of chromosome classification by multicolor karyotyping

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Nondisjunction of chromosomes leading to hyperdiploid childhood B-cell precursor acute lymphoblastic leukemia is an early event during leukemogenesis.

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Childhood leukemias

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Favorable prognosis associated with hyperdiploidy in children with acute lymphocytic leukemia correlates with extra chromosome 6. A Pediatric Oncology Group study

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Acute lymphoblastic leukaemia.

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Combined metaphase, interphase cytogenetic, and flow cytometric analysis of DNA content of pediatric acute lymphoblastic leukemia.

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Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

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Childhood acute lymphoblastic leukemia with the MLL-ENL fusion and t(11;19)(q23;p13.3) translocation

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Childhood leukaemia

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A highly specific and sensitive fluorescence in situ hybridization assay for the detection of t(4;11)(q21;q23) and concurrent submicroscopic deletions in acute leukaemias.

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Abnormalities of the ETV6 gene occur in the majority of patients with aberrations of the short arm of chromosome 12: a combined PCR and Southern blotting analysis

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A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line.

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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

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Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia

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AML1 gene over-expression in childhood acute lymphoblastic leukemia

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Identification of new translocations involving ETV6 in hematologic malignancies by fluorescence in situ hybridization and spectral karyotyping

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Deletion analysis of p16(INKa) and p15(INKb) in relapsed childhood acute lymphoblastic leukemia.

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Spectral karyotyping and multicolor fluorescence in situ hybridization reveal new tumor-specific chromosomal aberrations

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Acute leukemia cytogenetics: an evaluation of combining G-band karyotyping with multi-color spectral karyotyping

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Multicolor spectral karyotyping identifies novel translocations in childhood acute lymphoblastic leukemia

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Reassessment of childhood B-lineage lymphoblastic leukemia karyotypes using spectral analysis

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Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis

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Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party

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Interphase fluorescence in situ hybridization and spectral karyotyping reveals hidden genetic aberrations in children with acute lymphoblastic leukaemia and a normal banded karyotype

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Spectral karyotyping and interphase FISH reveal abnormalities not detected by conventional G-banding. Implications for treatment stratification of childhood acute lymphoblastic leukaemia: detailed analysis of 70 cases

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Hemizygous p16(INK4A) deletion in pediatric acute lymphoblastic leukemia predicts independent risk of relapse

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Prognostic impact of trisomies of chromosomes 10, 17, and 5 among children with acute lymphoblastic leukemia and high hyperdiploidy (> 50 chromosomes)

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The value of interphase fluorescence in situ hybridization for the detection of translocation t(12;21) in childhood acute lymphoblastic leukemia

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Quantitative analysis of TEL/AML1 fusion transcripts by real-time RT-PCR assay in childhood acute lymphoblastic leukemia

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Detection of prognostic significant translocations in childhood acute lymphoblastic leukaemia by one-step multiplex reverse transcription polymerase chain reaction

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Detection of chromosome over- and underrepresentations in hyperdiploid acute lymphoblastic leukemia by comparative genomic hybridization

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Differential binding of alkylating fluorochromes in human chromosomes

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Importance of the day 7 bone marrow biopsy as a prognostic measure of the outcome in children with acute lymphoblastic leukemia

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Treatment of acute lymphoblastic leukemia. 30 years' experience at St. Jude Children's Research Hospital

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Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia

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Gender and treatment outcome in childhood lymphoblastic leukaemia: report from the MRC UKALL trials

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Cytogenetic findings in a population-based series of 787 childhood acute lymphoblastic leukemias from the Nordic countries. The NOPHO Leukemia Cytogenetic Study Group

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FISH: a useful technique in the verification of clonality of random chromosome abnormalities

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Single-cell trisomy in hematologic malignancy. Random change or tip of the iceberg?

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Detection of hyperdiploid karyotypes (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) using fluorescence in situ hybridization (FISH)

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Acquired X-chromosome aneuploidy in children with acute lymphoblastic leukemia

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Detection of minimal residual disease in childhood acute lymphoblastic leukaemia using fluorescence in-situ hybridization

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Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia

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Poor treatment outcome of Philadelphia chromosome-positive pediatric acute lymphoblastic leukemia despite intensive chemotherapy

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From genes to therapy: the case of Philadelphia chromosome-positive leukemias.

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Deletions of the derivative chromosome 9 do not account for the poor prognosis associated with Philadelphia-positive acute lymphoblastic leukemia

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Derivative chromosomes of 11q23-translocations in hematologic malignancies. European 11q23 Workshop participants

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Fifteen cases of t(1;19)(q23;p13.3) identified in an Australian series of 122 children and 80 adults with acute lymphoblastic leukemia

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Novel cryptic, complex rearrangements involving ETV6-CBFA2 (TEL-AML1) genes identified by fluorescence in situ hybridization in pediatric patients with acute lymphoblastic leukemia

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Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup

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An investigation of the t(12;21) rearrangement in children with B-precursor acute lymphoblastic leukaemia using cytogenetic and molecular methods

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Cytogenetic abnormalities associated with the t(12;21): a collaborative study of 169 children with t(12;21)-positive acute lymphoblastic leukemia

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Amplification of AML1 in childhood acute lymphoblastic leukemias

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Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation

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Inactivation of the p15INK4B and p16INK4 genes in hematologic malignancies

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Enhanced expression of p16ink4a is associated with a poor prognosis in childhood acute lymphoblastic leukemia

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Genetic studies of childhood acute lymphoblastic leukemia with emphasis on p16, MLL, and ETV6 gene abnormalities: results of St Jude Total Therapy Study XII

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Preferential loss of maternal 9p alleles in childhood acute lymphoblastic leukemia

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Identifiers

10.1080/1042819031000083361

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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