(Q35666413)

English

The oligo-acyl lysyl antimicrobial peptide C₁₂K-2β₁₂ exhibits a dual mechanism of action and demonstrates strong in vivo efficacy against Helicobacter pylori

scientific article published on 7 November 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

The oligo-acyl lysyl antimicrobial peptide C₁₂K-2β₁₂ exhibits a dual mechanism of action and demonstrates strong in vivo efficacy against Helicobacter pylori (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Helicobacter pylori

1 reference

based on heuristic

inferred from title

Helicobacter pylori infectious disease

1 reference

based on heuristic

inferred from title

antimicrobial peptide

1 reference

based on heuristic

inferred from title

author name string

Morris O Makobongo

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Hanan Gancz

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Beth M Carpenter

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dennis P McDaniel

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

D Scott Merrell

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

0 references

publication date

7 November 2011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

56

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

378-390

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pylori

1 reference

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12 July 2018

A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis

1 reference

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12 July 2018

Mechanisms mediating bactericidal properties and conditions that enhance the potency of a broad-spectrum oligo-acyl-lysyl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features

1 reference

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12 July 2018

Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections

1 reference

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12 July 2018

Detailed in vivo analysis of the role of Helicobacter pylori Fur in colonization and disease

1 reference

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A miniature mimic of host defense peptides with systemic antibacterial efficacy

1 reference

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Epidemiological link between gastric disease and polymorphisms in VacA and CagA.

1 reference

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12 July 2018

Cell-wall interactions and the selective bacteriostatic activity of a miniature oligo-acyl-lysyl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

In vitro antibacterial activity of acyl-lysyl oligomers against Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Design of novel indolicidin-derived antimicrobial peptides with enhanced cell specificity and potent anti-inflammatory activity

1 reference

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12 July 2018

A single nucleotide change affects fur-dependent regulation of sodB in H. pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Quadruple therapy with furazolidone for retreatment in patients with peptic ulcer disease

1 reference

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12 July 2018

Impact of self-assembly properties on antibacterial activity of short acyl-lysine oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

New concepts of resistance in the treatment of Helicobacter pylori infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Structure-activity relationships of antibacterial acyl-lysine oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

A common mechanism of cellular death induced by bactericidal antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

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alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

American College of Gastroenterology guideline on the management of Helicobacter pylori infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Antiplasmodial activity of lauryl-lysine oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Peptide antimicrobial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Iron and pH homeostasis intersect at the level of Fur regulation in the gastric pathogen Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Activation of beta-catenin by carcinogenic Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Different anti-Candida activities of two human lactoferrin-derived peptides, Lfpep and kaliocin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Activation of the complement system generates antibacterial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

The relationship between peptide structure and antibacterial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Low eradication rate of Helicobacter pylori with triple 7-14 days and quadriple therapy in Turkey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Mechanisms of antimicrobial peptide action and resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Generation of Helicobacter pylori ghosts by PhiX protein E-mediated inactivation and their evaluation as vaccine candidates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Global analysis of Helicobacter pylori gene expression in human gastric mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Antimicrobial peptides of multicellular organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

The oxazolidinones as a new family of antimicrobial agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Comparison of the membrane association of two antimicrobial peptides, magainin 2 and indolicidin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Structure and mechanism of action of an indolicidin peptide derivative with improved activity against gram-positive bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Serum immunoglobulin G immune response to Helicobacter pylori antigens in Mongolian gerbils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Microtubules Are required for motility and positioning of vesicles and mitochondria in hyphal tip cells of Allomyces macrogynus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Structure-activity analysis of buforin II, a histone H2A-derived antimicrobial peptide: the proline hinge is responsible for the cell-penetrating ability of buforin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

A PhoP-regulated outer membrane protease of Salmonella enterica serovar typhimurium promotes resistance to alpha-helical antimicrobial peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Oxazolidinones: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Diversity of antimicrobial peptides and their mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Helicobacter pylori virulence and genetic geography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

The life and death of Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Experimental infection of Mongolian gerbils with wild-type and mutant Helicobacter pylori strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

The glycopeptide story--how to kill the deadly 'superbugs'.

1 reference

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Amoxicillin for the treatment of Helicobacter pylori infection

1 reference

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Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: a review

1 reference

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Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine

1 reference

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1 reference

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Compounds which increase the permeability of the Pseudomonas aeruginosa outer membrane

1 reference

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Molecular architecture and functioning of the outer membrane of Escherichia coli and other gram-negative bacteria

1 reference

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Damage of the outer membrane of enteric gram-negative bacteria by lactoferrin and transferrin

1 reference

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12 July 2018

Penicillin-binding proteins of gram-negative bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

12 July 2018

Design and characterization of a broad -spectrum bactericidal acyl-lysyl oligomer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

25 September 2018

Structure-activity relationship of human liver-expressed antimicrobial peptide 2.

1 reference

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The sodium-dependent D-glucose transport protein of Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

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Solution structure and refolding of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA.

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

25 September 2018

Analogous oligo-acyl-lysines with distinct antibacterial mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

25 September 2018

Empirical rescue therapy after Helicobacter pylori treatment failure: a 10-year single-centre study of 500 patients

1 reference

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25 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

25 September 2018

Improved antimicrobial peptides based on acyl-lysine oligomers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

25 September 2018

Chimeric streptogramin-tyrocidine antibiotics that overcome streptogramin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3256018

25 September 2018

Inactivation of Helicobacter pylori cagA gene affects motility.

1 reference

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25 September 2018

Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism.

1 reference

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25 September 2018

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1 reference

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25 September 2018

Tryptophan-rich antimicrobial peptides: comparative properties and membrane interactions

1 reference

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25 September 2018

Proteases in Escherichia coli and Staphylococcus aureus confer reduced susceptibility to lactoferricin B.

1 reference

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25 September 2018

Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation

1 reference

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25 September 2018

Translocation of a channel-forming antimicrobial peptide, magainin 2, across lipid bilayers by forming a pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The concentration-dependent membrane activity of cecropin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Additive effect of clarithromycin combined with 14-hydroxy clarithromycin, erythromycin, amoxycillin, metronidazole or omeprazole against Helicobacter pylori

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of Campylobacter pyloridis to antibiotics, bismuth and an acid-reducing agent in vitro--an ultrastructural study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lactoferricin B inhibits bacterial macromolecular synthesis in and

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the acid stability of azithromycin and erythromycin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of a post-antibiotic effect (PAE) of beta-lactams against Helicobacter pylori NCTC 11637

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptic ulcer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22064541

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00689-11

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

0 references

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