(Q35670541)

English

Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.

scientific article published on 13 June 2011

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scholarly article

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4 February 2020

Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer (English)

1 reference

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4 February 2020

1

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4 February 2020

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4 February 2020

David M. Virshup

12

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4 February 2020

author name string

A A Schmitt

2

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4 February 2020

C A Canning

3

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4 February 2020

A Alok

4

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4 February 2020

I C C Low

5

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4 February 2020

N Banerjee

6

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4 February 2020

V Utomo

8

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4 February 2020

C M Jones

9

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4 February 2020

S Pervaiz

10

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4 February 2020

E J Toone

11

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4 February 2020

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publication date

13 June 2011

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4 February 2020

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4 February 2020

31

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4 February 2020

2

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4 February 2020

213-225

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4 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2011.228

0 references

The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators

1 reference

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DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC.

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WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

1 reference

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12 July 2018

Anti-tumor and radiosensitization activities of the iron chelator HDp44mT are mediated by effects on intracellular redox status

1 reference

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Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

1 reference

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12 July 2018

A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers

1 reference

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The antitumor activity of the fungicide ciclopirox

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12 July 2018

Iron-sulfur proteins in health and disease

1 reference

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Carteriosulfonic acids A-C, GSK-3beta inhibitors from a Carteriospongia sp.

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A two-step model for colon adenoma initiation and progression caused by APC loss

1 reference

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12 July 2018

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

1 reference

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12 July 2018

Beta-catenin hits chromatin: regulation of Wnt target gene activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257471

12 July 2018

Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives

1 reference

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12 July 2018

Wnt signaling in development, disease and translational medicine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257471

12 July 2018

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257471

12 July 2018

A role for iron in Wnt signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257471

12 July 2018

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

1 reference

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12 July 2018

The Connectivity Map: a new tool for biomedical research

1 reference

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12 July 2018

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

1 reference

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12 July 2018

Effect on ribonucleotide reductase of novel lipophilic iron chelators: the desferri-exochelins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257471

12 July 2018

Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells.

1 reference

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12 July 2018

Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor

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Determination of subcutaneous tumor size in athymic (nude) mice

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Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

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12 July 2018

The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation: an EPR study.

1 reference

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25 September 2018

Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.

1 reference

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Sustained interactive Wnt and FGF signaling is required to maintain isthmic identity.

1 reference

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25 September 2018

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1 reference

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25 September 2018

Desazadesmethyldesferrithiocin analogues as orally effective iron chelators

1 reference

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Thermodynamics of metal ion binding. 1. Metal ion binding by wild-type carbonic anhydrase

1 reference

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THE BIOCHEMISTRY OF DESFERRIOXAMINE AND ITS RELATION TO IRON METABOLISM

1 reference

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1 reference

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12 December 2020

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10.1038/ONC.2011.228

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21666721%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21666721%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

Europe PubMed Central

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4 February 2020

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