(Q35671160)

9 August 2017

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title

The preneoplastic phenotype in murine mammary tumorigenesis (English)

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9 August 2017

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Medina D

1

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9 August 2017

publication date

1 October 2000

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Journal of Mammary Gland Biology and Neoplasia

9 August 2017

published in

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9 August 2017

volume

5

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9 August 2017

issue

4

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9 August 2017

page(s)

393-407

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Role of endocrine, autocrine, and paracrine interactions in the development of mammary hyperplasia in Wnt-1 transgenic mice

9 August 2017

cites work

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12 December 2020

Genetically engineered mouse models of mammary intraepithelial neoplasia

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12 December 2020

Mammary tumorigenesis in chemical carcinogen-treated mice. IV. Induction of mammary ductal hyperplasias

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12 December 2020

Immortalization phenotype dissociated from the preneoplastic phenotype in mouse mammary epithelial outgrowths in vivo

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12 December 2020

Acceleration of mammary neoplasia in transforming growth factor alpha transgenic mice by 7,12-dimethylbenzanthracene

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12 December 2020

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

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12 December 2020

Characterization of Int-5, a locus associated with early events in mammary carcinogenesis

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12 December 2020

Protein kinase C isozymes and substrates in mammary carcinogenesis

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12 December 2020

Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development

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12 December 2020

Delayed involution of the mammary epithelium in BALB/c-p53null mice

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12 December 2020

Cell cyclins and cyclin-dependent kinase activities in mouse mammary tumor development.

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12 December 2020

Mechanism-based cancer prevention approaches: targets, examples, and the use of transgenic mice.

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12 December 2020

The int-2 gene product acts as an epithelial growth factor in transgenic mice

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12 December 2020

Hyperplastic lesions of mouse mammary glands after treatment with 3-methylcholanthrene.

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12 December 2020

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

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12 December 2020

Regulation of growth and spacing of gland elements in the mammary fat pad of the C3H mouse

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12 December 2020

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands

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12 December 2020

Multiple RNAs expressed from the int-2 gene in mouse embryonal carcinoma cell lines encode a protein with homology to fibroblast growth factors

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12 December 2020

Effects of various oncogenic agents on tumor-producing capabilities of series D BALB-c mammary nodule outgrowth lines.

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12 December 2020

Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

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12 December 2020

Preferential overexpression of a 172Arg-->Leu mutant p53 in the mammary gland of transgenic mice results in altered lobuloalveolar development

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12 December 2020

Induction of mammary adenocarcinomas by medroxyprogesterone acetate in BALB/c female mice

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12 December 2020

Activation of H-ras oncogenes in preneoplastic mouse mammary tissues

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12 December 2020

The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors

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12 December 2020

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

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12 December 2020

Evidence of separate pathways for viral and chemical carcinogenesis in c3h/stwi mouse mammary glands

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12 December 2020

The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma

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12 December 2020

Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice

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12 December 2020

Immortalized mouse mammary cells in vivo do not exhibit increased telomerase activity.

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12 December 2020

Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis

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12 December 2020

p53 mutations selected in vivo when mouse mammary epithelial cells form hyperplastic outgrowths are not necessary for establishment of mammary cell lines in vitro

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12 December 2020

Serial transplantation of chemical carcinogen-induced mouse mammary ductal dysplasias

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12 December 2020

Tumorigenesis by mouse mammary tumor virus: Evidence for a common region for provirus integration in mammary tumors

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12 December 2020

The Sequential Analysis of Cancer Development

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12 December 2020

Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population

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12 December 2020

Radiation-induced apoptosis in normal and pre-neoplastic mammary glands in vivo: significance of gland differentiation and p53 status

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12 December 2020

The nature and expression of int-5, a novel MMTV integration locus gene in carcinogen-induced mammary tumors

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12 December 2020

Biological features of premalignant disease in the human breast

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12 December 2020

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development

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12 December 2020

Detection of ductal dysplasia in mammary outgrowths derived from carcinogen-treated virgin female BALB/c mice

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12 December 2020

Hyperplasia of mouse mammary epithelium induced by expression of the Wnt-1 (int-1) oncogene in reconstituted mammary gland

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12 December 2020

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

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12 December 2020

Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia

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12 December 2020

A common mouse mammary tumor virus integration site in chemically induced precancerous mammary hyperplasias

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12 December 2020

Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype

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12 December 2020

Morphological and functional properties of TM preneoplastic mammary outgrowths

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12 December 2020

Spontaneous progression of hyperplastic outgrowths of the D1 lineage to mammary tumors: expression of mouse mammary tumor virus and cellular proto-oncogenes

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12 December 2020

Enhancement of the Tumorigenicity of Preneoplastic Mammary Nodule Lines by Enzymatic Dissociation2

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12 December 2020

Expression of the mouse mammary tumor virus long terminal repeat open reading frame promotes tumorigenic potential of hyperplastic mouse mammary epithelial cells.

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12 December 2020

Restriction endonuclease studies of hyperplastic outgrowth lines from BALB/cfC3H mouse hyperplastic mammary nodules

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12 December 2020

Specific activation of the cellular Harvey-ras oncogene in dimethylbenzanthracene-induced mouse mammary tumors

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12 December 2020

Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

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12 December 2020

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12 December 2020

Development of mammary preneoplasias in vivo from mouse mammary epithelial cell lines in vitro

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12 December 2020

Interactions of apoptosis, proliferation and host age in the regression of the mouse mammary preneoplasia, TM3, carrying an unusual mutation in p53

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12 December 2020

Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis

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12 December 2020

Growth factor dependency and gene expression in preneoplastic mouse mammary epithelial cells.

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12 December 2020

Tumor Formation in Preneoplastic Mammary Nodule Lines in Mice Treated With Nafoxidine, Testosterone, and 2-Bromo- α -ergocryptine 2

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12 December 2020

Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain

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12 December 2020

Unlimited division potential of precancerous mouse mammary cells after spontaneous or carcinogen-induced transformation

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12 December 2020

Biochemical characteristics of mouse mammary tissues, preneoplastic lesions and tumors.

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12 December 2020

Mammary tumorigenesis in C3Hf/Ki mice: examination of germinal mouse mammary tumor viruses and the int-1 and int-2 putative proto-oncogenes.

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12 December 2020

Biology of breast preneoplasia

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12 December 2020

Mammary Tumorigenesis in Chemical Carcinogen-Treated Mice. VI. Tumor-Producing Capabilities of Mammary Dysplasias in BALB/cCrgl Mice2

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12 December 2020

Multistage Carcinogenesis: Population-Based Model for Colon Cancer

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12 December 2020

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

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12 December 2020

A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland

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12 December 2020

A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene

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12 December 2020

Protoneoplasia: The Molecular Biology of Murine Mammary Hyperplasia

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12 December 2020

Cyclins and breast cancer

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12 December 2020

Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cel

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12 December 2020

Stage specificity of selenium-mediated inhibition of mouse mammary tumorigenesis

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12 December 2020

Immortal, non-tumourigenic mouse mammary outgrowths express high levels of cyclin B1 and activation of cyclin B1/cdc2 kinase.

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12 December 2020

Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.

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12 December 2020

The mammary gland: a unique organ for the study of development and tumorigenesis

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12 December 2020

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

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12 December 2020

Gene control of neoplasia. I. Genotypic mosaicism in normal and preneoplastic mammary glands of allophenic mice

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12 December 2020

Aromatase overexpression and breast hyperplasia, an in vivo model--continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary gl

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12 December 2020

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

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12 December 2020

Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.

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12 December 2020

A transgenic mouse model for mammary carcinogenesis.

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12 December 2020

Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis

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12 December 2020

Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors

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12 December 2020

A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development

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12 December 2020

An entire functional mammary gland may comprise the progeny from a single cell

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12 December 2020

The biology of mammary transgenes: five rules

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12 December 2020

NEW METHOD FOR DETECTION OF MOUSE MAMMARY TUMOR VIRUS. I. INFLUENCE OF FOSTER NURSING ON INCIDENCE OF HYPERPLASTIC MAMMARY NODULES IN BALB/CCRGL MICE

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12 December 2020

The effect of parity, tumor latency and transplantation on the activation of int loci in MMTV-induced, transplanted C3H mammary pre-neoplasias and their tumors

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12 December 2020

A new site of integration for mouse mammary tumor virus proviral DNA common to BALB/cf(C3H) mammary and kidney adenocarcinomas

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12 December 2020

Int-2, an autocrine and/or ultra-short-range effector in transgenic mammary tissue transplants.

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12 December 2020

Expression of differentiation-specific proteins in preneoplastic mammary tissues in BALB/c mice

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12 December 2020

Detection of inapparent nodule-transformed cells in the mammary gland tissues of virgin female BALB/cfC3H mice

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12 December 2020

The overexpression of int-5/Aromatase, a novel MMTV integration locus gene, is responsible for D2 mammary tumor cell proliferation

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12 December 2020

Activation of endogenous MMTV proviruses in murine mammary cancer induced by chemical carcinogen.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1009529928422

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Dimensions Publication ID

9 August 2017

1021332305

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