(Q35674540)

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M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity.

scientific article published on 4 June 2008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524769%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity (English)

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8 January 2020

7

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8 January 2020

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Xiao-Bo Zhou

1

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8 January 2020

Iris Wulfsen

2

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8 January 2020

Susanne Lutz

3

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8 January 2020

Emine Utku

4

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8 January 2020

Ulrike Sausbier

5

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8 January 2020

Peter Ruth

6

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8 January 2020

Michael Korth

8

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8 January 2020

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4 June 2008

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8 January 2020

Journal of Biological Chemistry

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8 January 2020

283

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8 January 2020

30

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8 January 2020

21036-21044

1 reference

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8 January 2020

Oxytocin receptors differentially signal via Gq and Gi proteins in pregnant and nonpregnant rat uterine myocytes: implications for myometrial contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

High-conductance potassium channels of the SLO family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

BKCa-Cav channel complexes mediate rapid and localized Ca2+-activated K+ signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

A family of killer toxins. Exploring the mechanism of ADP-ribosylating toxins.

1 reference

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12 July 2018

Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Assembly of a Ca2+-dependent BK channel signaling complex by binding to beta2 adrenergic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Activation and deactivation kinetics of alpha 2A- and alpha 2C-adrenergic receptor-activated G protein-activated inwardly rectifying K+ channel currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Protein kinases: tuners of the BKCa channel in smooth muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

A molecular switch for specific stimulation of the BKCa channel by cGMP and cAMP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Calcium sparks in smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Cyclic GMP-dependent protein kinase activates cloned BKCa channels expressed in mammalian cells by direct phosphorylation at serine 1072.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Direct binding of G-protein betagamma complex to voltage-dependent calcium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Muscarinic receptor subtypes and smooth muscle function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Protein phosphatase 2A is essential for the activation of Ca2+-activated K+ currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Transfected m2 muscarinic acetylcholine receptors couple to G alpha i2 and G alpha i3 in Chinese hamster ovary cells. Activation and desensitization of the phospholipase C signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Role of G proteins and KCa channels in the muscarinic and beta-adrenergic regulation of airway smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Functional role of the β subunit of high conductance calcium-activated potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Muscarinic cholinergic inhibition of adenylate cyclase in airway smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Identification of a family of muscarinic acetylcholine receptor genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Muscarinic cholinergic inhibition of cyclic AMP accumulation in airway smooth muscle. Role of a pertussis toxin-sensitive protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Autoradiographic visualization of muscarinic receptor subtypes in human and guinea pig lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Coupling of transfected muscarinic acetylcholine receptor subtypes to phospholipase D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Muscarinic inhibition of single KCa channels in smooth muscle cells by a pertussis-sensitive G protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

12 July 2018

Targeting the protein kinase C family: are we there yet?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

25 September 2018

Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK,ACh channels in patients with chronic atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

25 September 2018

Protein kinase C inhibits BKCachannel activity in pulmonary arterial smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

25 September 2018

Melatonin receptor signaling in pregnant and nonpregnant rat uterine myocytes as probed by large conductance Ca2+-activated K+ channel activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

25 September 2018

M(3)-receptor knockout mice: muscarinic receptor function in atria, stomach fundus, urinary bladder, and trachea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

25 September 2018

Maxi-K(Ca), a Unique Member of the Voltage-Gated K Channel Superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258941

25 September 2018

Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800447200

21 January 2018

Probing cortical function with electrical stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800447200

21 January 2018

M2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol response to cholinergic agonists in airway smooth muscle: relationship to contraction and muscarinic receptor occupancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relaxation of arterial smooth muscle by calcium sparks

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a direct relationship between phosphoinositide metabolism and airway smooth muscle contraction induced by muscarinic agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visualization of muscarinic m4 mRNA and M4 receptor subtype in rabbit lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of signal-transducing guanine-nucleotide-binding regulatory proteins by guanosine 5'-[gamma-thio]triphosphate. Information transfer by intermediately thiophosphorylated beta gamma subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase C inhibits calcium-activated potassium channels in rat pituitary tumour cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnancy switches adrenergic signal transduction in rat and human uterine myocytes as probed by BKCa channel activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C modulates Ca2+-activated K+ channels in cultured rat mesenteric artery smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of muscarinic receptor subtypes in pig airways: radioligand binding and northern blotting studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C reduces the KCa current of rat tail artery smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18524769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M800447200

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524769%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524769%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18524769%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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