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Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.
scientific article published on 27 June 2008
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
title
Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
main subject
breast cancer
1 reference
based on heuristic
inferred from title
author
Dakang Xu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
author name string
Julie Dwyer
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
He Li
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Wei Duan
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Jun-Ping Liu
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
language of work or name
English
0 references
publication date
27 June 2008
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
volume
283
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
page(s)
23567-23580
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
issue
35
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
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PubMed Central
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Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family
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12 July 2018
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site
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PubMed Central
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12 July 2018
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene
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PubMed Central
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12 July 2018
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.
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PubMed Central
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12 July 2018
ETS transcription factors and their emerging roles in human cancer
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PubMed Central
reference URL
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12 July 2018
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA.
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12 July 2018
Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
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12 July 2018
hTERT antagonizes p53-induced apoptosis independently of telomerase activity.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
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12 July 2018
The structural and dynamic basis of Ets-1 DNA binding autoinhibition.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
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12 July 2018
Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
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12 July 2018
Ets proteins in biological control and cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
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12 July 2018
EWS/ETS fusions activate telomerase in Ewing's tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
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12 July 2018
Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
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12 July 2018
Ets2-dependent stromal regulation of mouse mammary tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Role of Ets/Id proteins for telomerase regulation in human cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Ets2 and protein kinase C epsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Proteins of the ETS family with transcriptional repressor activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Regulation of Ets function by protein - protein interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Altered Ets transcription factor activity in prostate tumor cells inhibits anchorage-independent growth, survival, and invasiveness
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Studies of the molecular mechanisms in the regulation of telomerase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Telomerase is controlled by protein kinase Calpha in human breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Defective trophoblast function in mice with a targeted mutation of Ets2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Ets-2 transdominant mutant abolishes anchorage-independent growth and macrophage colony-stimulating factor-stimulated invasion by BT20 breast carcinoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
12 July 2018
Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter--effect on telomerase expression and telomere length maintenance in non-small cell lung cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
25 September 2018
ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
25 September 2018
Identification and characterization of rapidly dividing U937 clones with differential telomerase activity and gene expression profiles: role of c-Myc/Mad1 and Id/Ets proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
25 September 2018
A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259778
retrieved
25 September 2018
TERT regulates cell survival independent of telomerase enzymatic activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18586674
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
ETS2 function is required to maintain the transformed state of human prostate cancer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18586674
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage-independent growth
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18586674
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M800790200
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PMCID
3259778
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PubMed ID
18586674
1 reference
stated in
Europe PubMed Central
PMCID
3259778
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18586674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
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