(Q35677422)

English

Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function

scientific article published on 18 December 2006

In more languages

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function (English)

1 reference

Europe PubMed Central

9 August 2017

photoreceptor protein

0 references

retinal degeneration

1 reference

based on heuristic

inferred from title

author name string

Yasutsugu Ishiba

1

1 reference

Europe PubMed Central

9 August 2017

Tomomi Higashide

2

1 reference

Europe PubMed Central

9 August 2017

Naoki Mori

3

1 reference

Europe PubMed Central

9 August 2017

Akira Kobayashi

4

1 reference

Europe PubMed Central

9 August 2017

Shinya Kubota

5

1 reference

Europe PubMed Central

9 August 2017

Margaret J McLaren

6

1 reference

Europe PubMed Central

9 August 2017

Hiromasa Satoh

7

1 reference

Europe PubMed Central

9 August 2017

Fulton Wong

8

1 reference

Europe PubMed Central

9 August 2017

George Inana

9

1 reference

Europe PubMed Central

9 August 2017

publication date

18 December 2006

1 reference

Europe PubMed Central

9 August 2017

Experimental Eye Research

1 reference

Europe PubMed Central

9 August 2017

84

1 reference

Europe PubMed Central

9 August 2017

3

1 reference

Europe PubMed Central

9 August 2017

473-485

1 reference

Europe PubMed Central

9 August 2017

Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Cone dystrophy phenotype associated with a frameshift mutation (M280fsX291) in the alpha-subunit of cone specific transducin (GNAT2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Photoreceptor synaptic protein HRG4 (UNC119) interacts with ARL2 via a putative conserved domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Mutant rhodopsin transgene expression on a null background

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Phototransduction in transgenic mice after targeted deletion of the rod transducin alpha -subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Characterization of the gene for HRG4 (UNC119), a novel photoreceptor synaptic protein homologous to unc-119

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Morphological, physiological, and biochemical changes in rhodopsin knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Localization of HRG4, a photoreceptor protein homologous to Unc-119, in ribbon synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Missense mutation in the gene encoding the alpha subunit of rod transducin in the Nougaret form of congenital stationary night blindness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Cloning of the cDNA for a novel photoreceptor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

The synaptic vesicle cycle: a cascade of protein-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Transsynaptic response of the lateral geniculate nucleus and the pattern of degeneration of the nerve terminals in the Rhesus monkey after eye enucleation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

A point mutation of the rhodopsin gene in one form of retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

12 July 2018

Truncation mutation in HRG4 (UNC119) leads to mitochondrial ANT-1-mediated photoreceptor synaptic and retinal degeneration by apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

unc-119 homolog required for normal development of the zebrafish nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Retinal abnormalities associated with the G90D mutation in opsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Phosducin facilitates light-driven transducin translocation in rod photoreceptors. Evidence from the phosducin knockout mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Retinal remodeling triggered by photoreceptor degenerations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Changes in retinal synaptic proteins in the transgenic model expressing a mutant HRG4 (UNC119).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Gene dosage effect of the TrkB receptor on rod physiology and biochemistry in juvenile mouse retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Gene therapy restores vision in a canine model of childhood blindness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

Oscillatory potentials in the retina: what do they reveal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1820979

25 September 2018

The rhodopsin cycle is preserved in IRBP "knockout" mice despite abnormalities in retinal structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17174953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HRG4 (UNC119) mutation found in cone-rod dystrophy causes retinal degeneration in a transgenic model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17174953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane protein diffusion sets the speed of rod phototransduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17174953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinopathy induced in mice by targeted disruption of the rhodopsin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17174953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for the target enzyme in deactivation of photoreceptor G protein in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17174953

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXER.2006.10.016

1 reference

Europe PubMed Central

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

ResearchGate publication ID

0 references

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