(Q35681878)

9 August 2017

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title

Cellular regulation of hepatic bile acid transport in health and cholestasis (English)

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9 August 2017

M Sawkat Anwer

1

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PubMed ID

14999673

9 August 2017

language of work or name

English

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publication date

1 March 2004

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9 August 2017

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9 August 2017

39

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9 August 2017

581-590

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9 August 2017

3

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Bile salt transporters: molecular characterization, function, and regulation

9 August 2017

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Bile acid regulation of hepatic physiology: III. Bile acids and nuclear receptors

21 January 2018

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Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles

21 January 2018

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Estradiol-17β-D-glucuronide induces endocytic internalization of Bsep in rats

21 January 2018

1 reference

Role of PP2B in cAMP-induced dephosphorylation and translocation of NTCP.

21 January 2018

1 reference

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

1 reference

Mechanism of inhibition of Raf-1 by protein kinase A.

21 January 2018

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Regulation of cholangiocyte bicarbonate secretion

21 January 2018

1 reference

7 January 2021

Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes

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7 January 2021

The superfamily of organic anion transporting polypeptides

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7 January 2021

Cl(-)-dependent secretory mechanisms in isolated rat bile duct epithelial units

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7 January 2021

Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions

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7 January 2021

Genetic defects in hepatobiliary transport.

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7 January 2021

Molecular alterations in hepatocyte transport mechanisms in acquired cholestatic liver disorders

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7 January 2021

Genes and cholestasis.

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7 January 2021

Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.

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7 January 2021

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

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7 January 2021

Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

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7 January 2021

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

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7 January 2021

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

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7 January 2021

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

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7 January 2021

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis

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7 January 2021

Nuclear receptor regulation of hepatic function

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7 January 2021

Signal transduction and hepatocellular bile acid transport: cross talk between bile acids and second messengers

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7 January 2021

Hepatobiliary transport

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7 January 2021

Expression of hepatic transporters OATP-C and MRP2 in primary sclerosing cholangitis.

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7 January 2021

Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.

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7 January 2021

Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

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7 January 2021

Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat.

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7 January 2021

Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors

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7 January 2021

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

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7 January 2021

Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice

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7 January 2021

Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. Mediation of transcriptional activation by Stat5.

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7 January 2021

Heat induces intracellular acidification in human A-431 cells: role of Na(+)-H+ exchange and metabolism

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7 January 2021

Regulation of activity and apical targeting of the Cl-/HCO3- exchanger in rat hepatocytes

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7 January 2021

T cell-monocyte interactions regulate epithelial physiology in a coculture model of inflammation

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7 January 2021

Short-term regulation of bile acid uptake by microfilament-dependent translocation of rat ntcp to the plasma membrane

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7 January 2021

Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver

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7 January 2021

Vesicle targeting to the apical domain regulates bile excretory function in isolated rat hepatocyte couplets.

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7 January 2021

Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation

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7 January 2021

A family of cAMP-binding proteins that directly activate Rap1

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7 January 2021

Evidence for the regulation of exocytic transport by protein phosphorylation

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7 January 2021

Role of phosphoinositides in the regulation of liver function

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7 January 2021

Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat.

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7 January 2021

ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)

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7 January 2021

Agonist-induced isotonic contraction of cultured mesangial cells after multiple passage

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7 January 2021

Receptor-mediated stimulation of taurocholate efflux from the rat hepatocyte and the ex vivo perfused rat liver

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7 January 2021

Calmodulin and calmodulin-regulated protein kinases as transducers of intracellular calcium signals

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7 January 2021

Mechanism of activation of the Na+/H+ exchanger by arginine vasopressin in hepatocytes

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7 January 2021

Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate

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7 January 2021

Hepatotoxic bile acids increase cytosolic Ca++ activity of isolated rat hepatocytes

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7 January 2021

Tauroursodeoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liver

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7 January 2021

Effects of Ca2+ agonists on cytosolic Ca2+ in isolated hepatocytes and on bile secretion in the isolated perfused rat liver

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7 January 2021

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

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7 January 2021

Effects of protein kinase C and cytosolic Ca2+ on exocytosis in the isolated perfused rat liver

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7 January 2021

Insulin-induced Ca(2+) entry in hepatocytes is important for PI 3-kinase activation, but not for insulin receptor and IRS-1 tyrosine phosphorylation

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7 January 2021

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

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7 January 2021

Mechanism of desensitization of the cloned vasopressin V1a receptor expressed in Xenopus oocytes.

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7 January 2021

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

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7 January 2021

Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes

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7 January 2021

Protein kinase C agonists inhibit bile secretion independently of effects on the microcirculation in the isolated perfused rat liver.

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7 January 2021

Characterization of the mouse bile salt export pump overexpressed in the baculovirus system

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7 January 2021

The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

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7 January 2021

Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver

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7 January 2021

Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets

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7 January 2021

Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes

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7 January 2021

Protein kinase C-dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells

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7 January 2021

The role of phosphoinositide 3-kinase lipid products in cell function

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7 January 2021

The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver

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7 January 2021

Regulation of endocytic-transcytotic pathways and bile secretion by phosphatidylinositol 3-kinase in rats.

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7 January 2021

Cell swelling-induced translocation of rat liver Na(+)/taurocholate cotransport polypeptide is mediated via the phosphoinositide 3-kinase signaling pathway

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7 January 2021

Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles

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7 January 2021

Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane

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7 January 2021

Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity

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7 January 2021

Protein kinase signaling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes

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7 January 2021

Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na+/taurocholate cotransport and Ntcp translocation

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7 January 2021

Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes

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7 January 2021

Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.

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7 January 2021

Canalicular export pumps traffic with polymeric immunoglobulin A receptor on the same microtubule-associated vesicle in rat liver

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7 January 2021

Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways

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7 January 2021

Control of the eukaryotic cell cycle by MAP kinase signaling pathways.

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7 January 2021

The MAPK signaling cascade

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7 January 2021

Regulation of taurocholate excretion by a hypo-osmolarity-activated signal transduction pathway in rat liver.

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7 January 2021

Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver

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7 January 2021

Glucagon-induced expression of the MAP kinase phosphatase MKP-1 in rat hepatocytes

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7 January 2021

Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats

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7 January 2021

Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'.

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7 January 2021

Protein phosphatases independently regulate vesicle movement and microtubule subpopulations in hepatocytes.

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7 January 2021

Role of protein phosphatases in cyclic AMP-mediated stimulation of hepatic Na+/taurocholate cotransport

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7 January 2021

Down-regulation by extracellular ATP of rat hepatocyte organic anion transport is mediated by serine phosphorylation of oatp1

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7 January 2021

Identifiers

DOI

10.1002/HEP.20090

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9 August 2017

1 reference

PubMed ID

14999673