(Q35682330)

9 August 2017

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title

Ca2+ channels as targets of neurological disease: Lambert-Eaton Syndrome and other Ca2+ channelopathies (English)

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Lambert-Eaton myasthenic syndrome

9 August 2017

main subject

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author name string

Michael T Flink

series ordinal

1

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9 August 2017

William D Atchison

series ordinal

2

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9 August 2017

publication date

1 December 2003

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Journal of Bioenergetics and Biomembranes

9 August 2017

published in

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9 August 2017

volume

35

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9 August 2017

issue

6

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9 August 2017

page(s)

697-718

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Potentiation by the beta subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel

9 August 2017

cites work

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12 December 2020

Lambert-Eaton myasthenic syndrome as an autoimmune calcium-channelopathy

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12 December 2020

Calcium channel subtypes for the sympathetic and parasympathetic nerves of guinea-pig atria

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12 December 2020

Ultrastructural localization of the acetylcholine receptor in myasthenia gravis and in its experimental autoimmune model

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12 December 2020

Interaction of synaptotagmin with voltage gated calcium channels: a role in Lambert-Eaton myasthenic syndrome?

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12 December 2020

Action of Lambert-Eaton myasthenic syndrome IgG at mouse motor nerve terminals

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12 December 2020

Effects of omega-agatoxin-IVA and omega-conotoxin-MVIIC on perineurial Ca++ and Ca(++)-activated K+ currents of mouse motor nerve terminals

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12 December 2020

Detailed analysis of neuromuscular transmission in a patient with the myasthenic syndrome sometimes associated with bronchogenic carcinoma

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12 December 2020

Structure and regulation of voltage-gated Ca2+ channels

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12 December 2020

Autonomic dysfunction and Eaton Lambert syndrome

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12 December 2020

Specificity of Lambert-Eaton myasthenic syndrome immunoglobulin for nerve terminal calcium channels

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12 December 2020

The nature of the antagonism between calcium and magnesium ions at the neuromuscular junction

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12 December 2020

P/Q-type calcium channels activate neighboring calcium-dependent potassium channels in mouse motor nerve terminals

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12 December 2020

Differential plasma membrane targeting of voltage-dependent calcium channel subunits expressed in a polarized epithelial cell line

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12 December 2020

Voltage-dependent potentiation of neuronal L-type calcium channels due to state-dependent phosphorylation.

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12 December 2020

Differential sensitivities of avian and mammalian neuromuscular junctions to inhibition of cholinergic transmission by omega-conotoxin GVIA

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12 December 2020

Incidence of serum anti-P/O-type and anti-N-type calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome

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12 December 2020

Neuroendocrine carcinoma of lung associated with bradycardia and episodic cardiac asystole

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12 December 2020

Conformational modification enhances myasthenogenicity in synthetic peptide of acetylcholine receptor alpha-subunit

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12 December 2020

P-type calcium channels blocked by the spider toxin ω-Aga-IVA

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12 December 2020

Autoimmunity in the Lambert-Eaton myasthenic syndrome

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12 December 2020

Calcium channels coupled to neurotransmitter release at dually innervated neuromuscular junctions in the newborn rat.

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12 December 2020

IgG from patients with Lambert-Eaton syndrome blocks voltage-dependent calcium channels

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12 December 2020

Effects of synthetic omega-conotoxin, a new type Ca2+ antagonist, on frog and mouse neuromuscular transmission

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12 December 2020

3,4-Diaminopyridine (DAP) in the treatment of Lambert-Eaton myasthenic syndrome (LEMS).

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12 December 2020

The proteins synaptotagmin and syntaxin are not general targets of Lambert-Eaton myasthenic syndrome autoantibody

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12 December 2020

Facilitation by 3,4-diaminopyridine of regenerative acetylcholine release from mouse motor nerve

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12 December 2020

A(2A) adenosine receptor facilitation of neuromuscular transmission: influence of stimulus paradigm on calcium mobilization

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12 December 2020

The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen

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12 December 2020

Lambert-Eaton myasthenic syndrome without anti-calcium channel antibody: adverse effect of calcium antagonist diltiazem

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12 December 2020

Plasma exchange and immunosuppressive drug treatment in the Lambert-Eaton myasthenic syndrome

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12 December 2020

Are cardiovascular reflexes more commonly impaired in patients with bronchial carcinoma?

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12 December 2020

Developmental expression of voltage-dependent calcium currents in identified mouse motoneurons

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12 December 2020

Electromyography and electric stimulation of nerves in diseases of motor unit; observations on myasthenic syndrome associated with malignant tumors

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12 December 2020

Calcium channel peptide can cause an autoimmune-mediated model of Lambert-Eaton myasthenic syndrome in rats

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12 December 2020

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel

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12 December 2020

Expression and antibody inhibition of P-type calcium channels in human small-cell lung carcinoma cells

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12 December 2020

Novel modulatory effect of L-type calcium channels at newly formed neuromuscular junctions.

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12 December 2020

Coding and noncoding variation of the human calcium-channel beta4-subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia

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12 December 2020

Effects of serum-fractions from patients with Eaton-Lambert syndrome on rat cortical synaptosomal [3H]acetylcholine release

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12 December 2020

Two types of calcium channels coexist in peptide-releasing vertebrate nerve terminals

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12 December 2020

Altered expression and assembly of N-type calcium channel alpha1B and beta subunits in epileptic lethargic (lh/lh) mouse

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12 December 2020

Evidence for a dihydropyridine-sensitive and conotoxin-insensitive release of noradrenaline and uptake of calcium in adrenal chromaffin cells

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12 December 2020

Cerebellar cell degeneration in the leaner mutant mouse

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12 December 2020

Ca(2+)-dependent inactivation of P-type calcium channels in nerve terminals

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12 December 2020

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

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12 December 2020

Sera from Patients with Lambert-Eaton Myasthenic Syndrome Recognize the ?-Subunit of Ca2+Channel Complexes

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12 December 2020

Calcium channels involved in synaptic transmission at the mature and regenerating mouse neuromuscular junction

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12 December 2020

Neuronal calcium channels as target for Lambert-Eaton myasthenic syndrome autoantibodies.

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12 December 2020

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release

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12 December 2020

Synaptotagmin: a calcium sensor on the synaptic vesicle surface

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12 December 2020

Decreased calcium currents in motor nerve terminals of mice with Lambert-Eaton myasthenic syndrome

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12 December 2020

Lambert-Eaton myasthenic syndrome immunoglobulins react with multiple types of calcium channels in small-cell lung carcinoma

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12 December 2020

A randomized trial of 3,4-diaminopyridine in Lambert-Eaton myasthenic syndrome

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12 December 2020

Are the presynaptic membrane particles the calcium channels?

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12 December 2020

Voltage-dependent Ca2+ channels in small cell carcinomas are blocked by autoantibodies from patients with Lambert-Eaton myasthenic syndrome

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12 December 2020

Selected IgG rapidly induces Lambert-Eaton myasthenic syndrome in mice: complement independence and EMG abnormalities

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12 December 2020

Specificity of the Lambert-Eaton syndrome antibodies. Downregulation of P/Q-type calcium channels in bovine adrenal chromaffin cells

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12 December 2020

Multiple subtypes of voltage-gated calcium channel mediate transmitter release from parasympathetic neurons in the mouse bladder

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12 December 2020

Antibodies to calcium channel and synaptotagmin in Lambert-Eaton myasthenic syndrome

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12 December 2020

Increased frequency of IgG heavy chain marker Glm(2) and of HLA-B8 in Lambert-Eaton myasthenic syndrome with and without associated lung carcinoma

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12 December 2020

Autoantibodies bind solubilized calcium channel-omega-conotoxin complexes from small cell lung carcinoma: a diagnostic aid for Lambert-Eaton myasthenic syndrome

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12 December 2020

Study of cardiovascular autonomic insufficiency in advanced cancer patients

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12 December 2020

Disruption of synaptosomal calcium channel function by Lambert-Eaton myasthenic immunoglobulin is serum-dependent

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12 December 2020

Calcium-channel antibodies in the Lambert-Eaton syndrome and other paraneoplastic syndromes

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12 December 2020

Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4

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12 December 2020

Lambert-Eaton myasthenic syndrome: evidence for calcium channel blockade

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12 December 2020

Antibodies against the calcium channel beta-subunit in Lambert-Eaton myasthenic syndrome.

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12 December 2020

Iberiotoxin-induced block of Ca2+-activated K+ channels induces dihydropyridine sensitivity of ACh release from mammalian motor nerve terminals

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12 December 2020

Interference with Calcium Channels by Lambert Eaton Myasthenic Syndrome Antibody

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12 December 2020

The biochemistry of complement

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12 December 2020

Secondary changes of the motor endplate in Lambert-Eaton myasthenic syndrome: a quantitative study

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12 December 2020

Recombinant calcium channel is recognized by Lambert-Eaton myasthenic syndrome antibodies

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12 December 2020

Binding of Lambert-Eaton myasthenic syndrome IgG to synaptosomal proteins does not correlate with an inhibition of calcium uptake

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12 December 2020

Voltage-dependent ion channels in small-cell lung cancer cells.

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12 December 2020

Down-regulation of non-L-, non-N-type (Q-like) Ca2+ channels by Lambert-Eaton myasthenic syndrome (LEMS) antibodies in rat insulinoma RINm5F cells

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12 December 2020

Orthostatic hypotension in bronchial carcinoma

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12 December 2020

Histometric analysis of the ultrastructure of the neuromuscular junction in myasthenia gravis and in the myasthenic syndrome

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12 December 2020

Lambert-Eaton myasthenic syndrome: immunoglobulin G inhibition of Ca2+ flux in tumor cells correlates with disease severity

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12 December 2020

Protein kinase C is involved in M1-muscarinic receptor-mediated facilitation of L-type Ca2+ channels in neurons of the major pelvic ganglion of the adult male rat.

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12 December 2020

Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zones

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12 December 2020

Antibodies to synthetic peptides of the alpha1A subunit of the voltage-gated calcium channel in Lambert-Eaton myasthenic syndrome

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12 December 2020

On the release of transmitter at normal, myasthenia gravis and myasthenic syndrome affected human end-plates.

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12 December 2020

Importance of the different beta subunits in the membrane expression of the alpha1A and alpha2 calcium channel subunits: studies using a depolarization-sensitive alpha1A antibody

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12 December 2020

The human leukocyte antigen (HLA) system: 1990.

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12 December 2020

Autoimmune aetiology for myasthenic (Eaton-Lambert) syndrome

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12 December 2020

Increased frequency of HLA class II alleles DRB1*0301 and DQB1*0201 in Lambert-Eaton myasthenic syndrome without associated cancer

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12 December 2020

Calcium channel subtypes controlling serotonin release from human small cell lung carcinoma cell lines

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12 December 2020

Inhibition of calcium currents and exocytosis by Lambert-Eaton syndrome antibodies in human lung cancer cells

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12 December 2020

Multiple types of calcium channels mediate transmitter release during functional recovery of botulinum toxin type A-poisoned mouse motor nerve terminals

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12 December 2020

Specificity of calcium channel autoantibodies in Lambert-Eaton myasthenic syndrome

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12 December 2020

Calcium channel autoantibodies in Lambert-Eaton myasthenic syndrome

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12 December 2020

Myasthenic syndromes in hypothyroidism. Electrophysiological study of neuromuscular transmission and muscle contraction in two patients.

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12 December 2020

Antibodies to recombinant synaptotagmin and calcium channel subtypes in Lambert-Eaton myasthenic syndrome

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12 December 2020

Lambert-Eaton syndrome antibodies inhibit acetylcholine release and P/Q-type Ca2+ channels in electric ray nerve endings

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12 December 2020

Human autoantibodies specific for the alpha1A calcium channel subunit reduce both P-type and Q-type calcium currents in cerebellar neurons.

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12 December 2020

Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons

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12 December 2020

Regression of small-cell lung carcinoma in patients with paraneoplastic neuronal antibodies

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12 December 2020

mu-Opioid receptor-mediated reduction of neuronal calcium current occurs via a G(o)-type GTP-binding protein

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12 December 2020

The biophysical pharmacology of calcium-dependent acetylcholine secretion.

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12 December 2020

Paraneoplastic myasthenic syndrome IgG inhibits 45Ca2+ flux in a human small cell carcinoma line

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12 December 2020

Further study of the role of calcium in synaptic transmission

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12 December 2020

Adverse effect of verapamil in a patient with the Lambert-Eaton syndrome

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12 December 2020

Lambert-Eaton syndrome IgG inhibits dihydropyridine-sensitive, slowly inactivating calcium channels in bovine adrenal chromaffin cells

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12 December 2020

Calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome

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12 December 2020

Roles of a membrane-localized beta subunit in the formation and targeting of functional L-type Ca2+ channels

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12 December 2020

Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells

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12 December 2020

Calcium action in synaptic transmitter release

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12 December 2020

HLA class I and II in Lambert-Eaton myasthenic syndrome without associated tumor

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12 December 2020

Myasthenogenicity in the main immunogenic region of acetylcholine receptor as modified by conformational design: an approach to antigenic synthetic peptides

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12 December 2020

Coupling of L-type calcium channels to neurotransmitter release at mouse motor nerve terminals.

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12 December 2020

The action of Lambert-Eaton myasthenic syndrome immunoglobulin G on cloned human voltage-gated calcium channels

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12 December 2020

Eaton-Lambert syndrome: Acetylcholine and choline acetyltransferase in skeletal muscle

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12 December 2020

Serum and plasma from patients with Lambert-Eaton myasthenic syndrome reduce depolarization-dependent uptake of 45Ca2+ into rat cortical synaptosomes

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12 December 2020

Lambert-Eaton sera reduce low-voltage and high-voltage activated Ca2+ currents in murine dorsal root ganglion neurons

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12 December 2020

Specificity of autoantibodies react with omega-conotoxin MVIIC-sensitive calcium channel in Lambert-Eaton myasthenic syndrome

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12 December 2020

Neurotransmitter release from synaptotagmin-deficient clonal variants of PC12 cells

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12 December 2020

Calcium channel blockers and transmitter release at the normal human neuromuscular junction

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12 December 2020

Cross-linking of presynaptic calcium channels: a mechanism of action for Lambert-Eaton myasthenic syndrome antibodies at the mouse neuromuscular junction

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12 December 2020

Effects of Ca2+ channel blockers on transmitter release and presynaptic currents at the frog neuromuscular junction

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12 December 2020

Passive transfer of Lambert-Eaton myasthenic syndrome induces dihydropyridine sensitivity of ICa in mouse motor nerve terminals

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12 December 2020

The roles of the subunits in the function of the calcium channel.

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12 December 2020

Passive transfer of Lambert-Eaton myasthenic syndrome in mice: decreased rates of resting and evoked release of acetylcholine from skeletal muscle

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12 December 2020

Ultrastructural study of the motor end-plate in botulism and Lambert-Eaton myasthenic syndrome.

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12 December 2020

Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice

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12 December 2020

Inhibition of low- and high-threshold Ca2+ channels of human neuroblastoma IMR32 cells by Lambert-Eaton myasthenic syndrome (LEMS) IgGs

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12 December 2020

Colocalization of calcium entry and exocytotic release sites in adrenal chromaffin cells

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12 December 2020

Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release

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12 December 2020

Decreased calcium influx into the neonatal rat motor nerve terminals can recruit additional neuromuscular junctions during the synapse elimination period

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12 December 2020

Abnormalities of autonomic function in the Lambert Eaton myasthenic syndrome

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12 December 2020

Lambert-Eaton myasthenic syndrome IgG depletes presynaptic membrane active zone particles by antigenic modulation

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12 December 2020

Inhibitory action of Lambert-Eaton syndrome IgG on calcium currents in a thyroid C-cell line

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12 December 2020

Passive transfer of Lambert-Eaton syndrome to mice induces dihydropyridine sensitivity of neuromuscular transmission

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12 December 2020

Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen

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12 December 2020

Voltage-operated calcium channels in small cell lung carcinoma cell lines: pharmacological, functional, and immunological properties

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12 December 2020

Differential Ca2+-dependence of transmitter release mediated by P/Q- and N-type calcium channels at neonatal rat neuromuscular junctions.

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12 December 2020

The Eaton-Lambert syndrome and autoimmune disorders

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12 December 2020

Calcium Spike Electrogenesis and Other Electrical Activity in Continuously Cultured Small Cell Carcinoma of the Lung

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12 December 2020

Hypothyroid myopathy. Clinical, electromyographical, and ultrastructural observations

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12 December 2020

Presynaptic calcium signals and transmitter release are modulated by calcium-activated potassium channels

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12 December 2020

Heterogeneity of calcium channel autoantibodies detected using a small-cell lung cancer line derived from a Lambert-Eaton myasthenic syndrome patient

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12 December 2020

Human epilepsy associated with dysfunction of the brain P/Q-type calcium channel

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12 December 2020

A note of the mechanism by which inhibitors of the sodium pump accelerate spontaneous release of transmitter from motor nerve terminals

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12 December 2020

Functional evaluation of inhibition of autonomic transmitter release by autoantibody from Lambert-Eaton myasthenic syndrome

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12 December 2020

Linear B-cell epitopes in Lambert-Eaton myasthenic syndrome defined by cell-free synthetic peptide binding

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12 December 2020

Cholinergic dysautonomia and Eaton-Lambert syndrome

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12 December 2020

Mutations in the Cacnl1a4 calcium channel gene are associated with seizures, cerebellar degeneration, and ataxia in tottering and leaner mutant mice

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12 December 2020

Lambert-Eaton myasthenic syndrome: II. Immunoelectron microscopy localization of IgG at the mouse motor end-plate

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12 December 2020

The effect of myasthenic syndrome antibody on presynaptic calcium channels in the mouse

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12 December 2020

A myasthenic syndrome associated with bronchial carcinoma

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12 December 2020

Reduction of calcium currents by Lambert-Eaton syndrome sera: motoneurons are preferentially affected, and L-type currents are spared

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12 December 2020

Lambert-Eaton myasthenic syndrome: the lack of short-term in vitro effects of serum factors on neuromuscular transmission

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12 December 2020

Lambert-eation myasthenic syndrome

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12 December 2020

Selective action of myasthenic syndrome antibodies on calcium channels in a rodent neuroblastoma x glioma cell line

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12 December 2020

Postnatal development of serotonergic innervation, 5-HT1A receptor expression, and 5-HT responses in rat motoneurons

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12 December 2020

Quantal components of end-plate potentials in the myasthenic syndrome

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12 December 2020

Autonomic dysfunction in Lambert-Eaton myasthenic syndrome

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12 December 2020

Lambert-Eaton myasthenic syndrome: I. Early morphological effects of IgG on the presynaptic membrane active zones

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12 December 2020

Synaptotagmin can cause an immune-mediated model of Lambert-Eaton myasthenic syndrome in rats

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12 December 2020

Calcium channelopathies

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12 December 2020

Influence of stimulation on Ca(2+) recruitment triggering [3H]acetylcholine release from the rat motor-nerve endings

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12 December 2020

Calcium channels coupled to neurotransmitter release at neonatal rat neuromuscular junctions.

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12 December 2020

Antigens associated with N- and L-type calcium channels in Lambert-Eaton myasthenic syndrome.

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12 December 2020

Clinical, neurophysiological and morphological findings in Eaton Lambert syndrome

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12 December 2020

Low-dose guanidine and pyridostigmine: relatively safe and effective long-term symptomatic therapy in Lambert-Eaton myasthenic syndrome

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12 December 2020

AAEE Minimonograph #33: electrodiagnostic approach to defects of neuromuscular transmission

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12 December 2020

Reduced voltage sensitivity of activation of P/Q-type Ca2+ channels is associated with the ataxic mouse mutation rolling Nagoya (tg(rol))

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12 December 2020

The biochemistry of opsonization: central role of the reactive thiolester of the third component of complement

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12 December 2020

Strategic location of calcium channels at transmitter release sites of frog neuromuscular synapses

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12 December 2020

Functional dependence of Ca(2+)-activated K+ current on L- and N-type Ca2+ channels: differences between chicken sympathetic and parasympathetic neurons suggest different regulatory mechanisms

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12 December 2020

Calcium channels and channelopathies of the central nervous system

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12 December 2020

Differential blockade by nifedipine and omega-conotoxin GVIA of alpha 1- and beta 1-adrenoceptor-controlled calcium channels on motor nerve terminals of the rat

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12 December 2020

MHC molecules as peptide receptors

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12 December 2020

Lambert-Eaton myasthenic syndrome IgG: early morphologic effects and immunolocalization at the motor endplate

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12 December 2020

Role of N-, P- and Q-type voltage-gated calcium channels in transmitter release from sympathetic neurones in the mouse isolated vas deferens

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12 December 2020

Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse

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12 December 2020

Effect of Lambert-Eaton myasthenic syndrome antibodies on autonomic neurons in the mouse

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12 December 2020

Absence epilepsy in tottering mutant mice is associated with calcium channel defects

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12 December 2020

Passive transfer of the Lambert-Eaton myasthenic syndrome: neuromuscular transmission in mice injected with plasma

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12 December 2020

Response of the Lambert-Eaton myasthenic syndrome to treatment of associated small-cell lung carcinoma

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12 December 2020

The c3-activator system: an alternate pathway of complement activation.

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12 December 2020

Lambert-Eaton antibodies inhibit Ca2+ currents but paradoxically increase exocytosis during stimulus trains in bovine adrenal chromaffin cells

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12 December 2020

Inhibition of mitosis by an antibody to the mitotic calcium transport system

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12 December 2020

10.1023/B:JOBB.0000008033.02320.10

Identifiers

DOI

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Dimensions Publication ID

9 August 2017

1045197851

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