(Q35683181)

9 August 2017

title

A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis (English)

1 reference

9 August 2017

1 reference

C A Whipple

1

1 reference

9 August 2017

A L Young

series ordinal

2

1 reference

9 August 2017

M Korc

series ordinal

3

1 reference

9 August 2017

language of work or name

English

0 references

publication date

26 September 2011

1 reference

9 August 2017

1 reference

9 August 2017

volume

31

1 reference

9 August 2017

issue

20

1 reference

9 August 2017

page(s)

2535-2544

1 reference

Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

9 August 2017

cites work

1 reference

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12 July 2018

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Kinase signaling pathways as targets for intervention in pancreatic cancer

12 July 2018

1 reference

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Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis

12 July 2018

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

12 July 2018

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Galectin 1 proangiogenic and promigratory effects in the Hs683 oligodendroglioma model are partly mediated through the control of BEX2 expression

12 July 2018

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Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia

12 July 2018

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12 July 2018

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Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

12 July 2018

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Pancreatic stellate cells and pancreatic cancer cells: an unholy alliance.

12 July 2018

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Cancer-associated stromal fibroblasts promote pancreatic tumor progression

12 July 2018

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Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells

12 July 2018

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12 July 2018

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Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

12 July 2018

1 reference

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Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

12 July 2018

1 reference

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Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells

12 July 2018

1 reference

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Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer

12 July 2018

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

12 July 2018

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Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

12 July 2018

1 reference

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Identification of genes involved in cell invasion by using a library of randomized hybrid ribozymes

12 July 2018

1 reference

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Genetic alterations in pancreatic carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Pathways for aberrant angiogenesis in pancreatic cancer

12 July 2018

1 reference

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Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis

12 July 2018

1 reference

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Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas

12 July 2018

1 reference

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

12 July 2018

1 reference

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12 July 2018

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Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Glypican-1 is a VEGF165 binding proteoglycan that acts as an extracellular chaperone for VEGF165

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Isolation of full-length putative rat lysophospholipase cDNA using improved methods for mRNA isolation and cDNA cloning

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Effects of dietary manganese deficiency on rat pancreatic amylase mRNA levels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Soluble type II transforming growth factor-beta receptor attenuates expression of metastasis-associated genes and suppresses pancreatic cancer cell metastasis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Do morphogen gradients arise by diffusion?

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Mechanisms underlying preferential assembly of heparan sulfate on glypican-1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells

25 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262079

25 September 2018

https://api.crossref.org/works/10.1038%2FONC.2011.430

Radiosensitivity with Par-4 expression in prostate cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2011.430

Preparation, culture, and immortalization of mouse embryonic fibroblasts

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21996748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2011.430

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference

9 August 2017

1 reference