(Q35684572)

25744294

9 August 2017

title

The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells (English)

1 reference

9 August 2017

0 references

4

1 reference

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5 June 2020

Jin Chen

6

1 reference

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5 June 2020

author name string

Wei Bin Fang

1

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5 June 2020

Min Yao

2

1 reference

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5 June 2020

Iman Jokar

3

1 reference

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5 June 2020

Cory Berkland

5

1 reference

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5 June 2020

Dana Brantley-Sieders

7

1 reference

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5 June 2020

Nikki Cheng

8

1 reference

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5 June 2020

language of work or name

English

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publication date

6 March 2015

1 reference

25744294

Breast Cancer Research and Treatment

9 August 2017

published in

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5 June 2020

volume

150

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5 June 2020

issue

2

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5 June 2020

page(s)

309-320

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https://scigraph.springernature.com/pub.10.1007/s10549-015-3324-4

5 June 2020

exact match

0 references

cites work

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27 July 2018

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27 July 2018

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CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 protein- and p42/44 mitogen-activated protein kinase (MAPK)-dependent mechanisms

27 July 2018

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Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype

27 July 2018

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Critical role of hypoxia sensor--HIF-1α in VEGF gene activation. Implications for angiogenesis and tissue injury healing

27 July 2018

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Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer

27 July 2018

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Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer

27 July 2018

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Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis

27 July 2018

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Determination of cell survival or death.

27 July 2018

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27 July 2018

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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

27 July 2018

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Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression

27 July 2018

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Centrally necrotizing carcinoma of the breast: clinicopathological analysis of 33 cases indicating its basal-like phenotype and poor prognosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Loss of transforming growth factor-beta signaling in mammary fibroblasts enhances CCL2 secretion to promote mammary tumor progression through macrophage-dependent and -independent mechanisms

27 July 2018

1 reference

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The chemokine system in experimental and clinical hematology

27 July 2018

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siRNA delivery using nanocarriers - an efficient tool for gene silencing

27 July 2018

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Over-expression of angiotensin II type 2 receptor gene induces cell death in lung adenocarcinoma cells

27 July 2018

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CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells

27 July 2018

1 reference

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"Soft" calcium crosslinks enable highly efficient gene transfection using TAT peptide

27 July 2018

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Low-risk susceptibility alleles in 40 human breast cancer cell lines

27 July 2018

1 reference

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Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

The roles of chemokine CXCL12 in embryonic and brain tumor angiogenesis

27 July 2018

1 reference

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Tumor resistance to apoptosis

27 July 2018

1 reference

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CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation

27 July 2018

1 reference

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The roles of therapy-induced autophagy and necrosis in cancer treatment

27 July 2018

1 reference

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Chemokines in idiopathic inflammatory myopathies

27 July 2018

1 reference

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High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization

27 July 2018

1 reference

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Oestrogen receptor negative breast cancers exhibit high cytokine content

27 July 2018

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

27 July 2018

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A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis

27 July 2018

1 reference

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CCL2 is a potent regulator of prostate cancer cell migration and proliferation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Chemoattractants, extracellular proteases, and the integrated host defense response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

LC3 conjugation system in mammalian autophagy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Xenograft models of premalignant breast disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Transgenic Polyoma middle-T mice model premalignant mammary disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Role of the first extracellular loop in the functional activation of CCR2. The first extracellular loop contains distinct domains necessary for both agonist binding and transmembrane signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

The third helix of the Antennapedia homeodomain translocates through biological membranes.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Progesterone receptor status and Ki-67 index may predict early relapse in luminal B/HER2 negative breast cancer patients: a retrospective study

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Predicting drug responsiveness in human cancers using genetically engineered mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Luminal-B breast cancer and novel therapeutic targets

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Chemotherapy induces tumor clearance independent of apoptosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Necrosis and hypoxia in invasive breast carcinoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456035

Aberrant glycosphingolipid expression and membrane organization in tumor cells: consequences on tumor-host interactions

25 September 2018

1 reference

12 December 2020

Prognostic significance of necrosis, elastosis, fibrosis and inflammatory cell reaction in operable breast cancer

1 reference

12 December 2020

Chemokines in health and disease

1 reference

12 December 2020

Cross-species comparisons of cancer signaling

1 reference

12 December 2020

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

12 December 2020

Ex vivo assessment of chemotherapy-induced apoptosis and associated molecular changes in patient tumor samples

1 reference

12 December 2020

Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer

1 reference

12 December 2020

10.1007/S10549-015-3324-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25744294%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25744294%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

25744294

1 reference