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NKG2D Receptor and Its Ligands in Host Defense
scientific article published on June 2015
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
NKG2D Receptor and Its Ligands in Host Defense
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
author name string
Lewis L Lanier
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
language of work or name
English
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based on heuristic
inferred from title
publication date
1 June 2015
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stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
published in
Cancer Immunology Research
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
volume
3
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
page(s)
575-582
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
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Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients
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12 July 2018
A truncated human NKG2D splice isoform negatively regulates NKG2D-mediated function.
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12 July 2018
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation
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12 July 2018
Structural basis for recognition of cellular and viral ligands by NK cell receptors
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12 July 2018
NKG2D CARs as cell therapy for cancer
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New prospects on the NKG2D/NKG2DL system for oncology
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A selective role of NKG2D in inflammatory and autoimmune diseases
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Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ.
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12 July 2018
Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D
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NKG2D ligands as therapeutic targets
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Regulation of ligands for the NKG2D activating receptor
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RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry
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12 July 2018
The human herpesvirus-7 (HHV-7) U21 immunoevasin subverts NK-mediated cytoxicity through modulation of MICA and MICB
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Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the γc cytokines and TGF-β1.
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12 July 2018
The human NKG2D ligand ULBP2 can be expressed at the cell surface with or without a GPI anchor and both forms can activate NK cells.
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PubMed Central
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12 July 2018
Intracellular sequestration of the NKG2D ligand ULBP3 by human cytomegalovirus.
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12 July 2018
Post-translational modification of the NKG2D ligand RAET1G leads to cell surface expression of a glycosylphosphatidylinositol-linked isoform
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12 July 2018
TGF-beta downregulates the activating receptor NKG2D on NK cells and CD8+ T cells in glioma patients
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PubMed Central
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12 July 2018
Differential mechanisms of shedding of the glycosylphosphatidylinositol (GPI)-anchored NKG2D ligands
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PubMed Central
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12 July 2018
NKG2D ligand MICA is retained in the cis-Golgi apparatus by human cytomegalovirus protein UL142.
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PubMed Central
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12 July 2018
Differential susceptibility of RAE-1 isoforms to mouse cytomegalovirus
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PubMed Central
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12 July 2018
Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15.
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PubMed Central
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12 July 2018
Naive mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules
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Mononuclear myeloid-derived "suppressor" cells express RAE-1 and activate natural killer cells
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Interleukin-12 improves cytotoxicity of natural killer cells via upregulated expression of NKG2D.
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12 July 2018
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy
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12 July 2018
Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity
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12 July 2018
Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D
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12 July 2018
Host immune system gene targeting by a viral miRNA
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12 July 2018
Zoonotic orthopoxviruses encode a high-affinity antagonist of NKG2D
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PubMed Central
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12 July 2018
Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands.
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12 July 2018
Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity
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PubMed Central
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12 July 2018
The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.
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PubMed Central
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12 July 2018
NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells
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12 July 2018
IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells
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PubMed Central
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12 July 2018
Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
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12 July 2018
Function of NKG2D in natural killer cell-mediated rejection of mouse bone marrow grafts
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12 July 2018
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
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12 July 2018
The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure.
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12 July 2018
Engagement of NKG2D by cognate ligand or antibody alone is insufficient to mediate costimulation of human and mouse CD8+ T cells.
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12 July 2018
NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145.
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12 July 2018
The cytomegalovirus m155 gene product subverts natural killer cell antiviral protection by disruption of H60-NKG2D interactions
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PubMed Central
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12 July 2018
Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shedding in prostate cancer
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12 July 2018
A Structural basis for the association of DAP12 with mouse, but not human, NKG2D
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12 July 2018
Role of NKG2D signaling in the cytotoxicity of activated and expanded CD8+ T cells
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PubMed Central
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12 July 2018
NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules
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12 July 2018
Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells
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PubMed Central
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12 July 2018
Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
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PubMed Central
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12 July 2018
NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation
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PubMed Central
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12 July 2018
Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.
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12 July 2018
The role of the NKG2D immunoreceptor in immune cell activation and natural killing
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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12 July 2018
A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3
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PubMed Central
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12 July 2018
NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment
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PubMed Central
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12 July 2018
Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo
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PubMed Central
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12 July 2018
Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
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PubMed Central
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12 July 2018
ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
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PubMed Central
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12 July 2018
Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells
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PubMed Central
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12 July 2018
DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells
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PubMed Central
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12 July 2018
Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice
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PubMed Central
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12 July 2018
An activating immunoreceptor complex formed by NKG2D and DAP10
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PubMed Central
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12 July 2018
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
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PubMed Central
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12 July 2018
The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex
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PubMed Central
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12 July 2018
Murine Nkg2d and Cd94 are clustered within the natural killer complex and are expressed independently in natural killer cells
1 reference
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PubMed Central
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12 July 2018
Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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12 July 2018
Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules
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PubMed Central
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12 July 2018
DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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12 July 2018
Secretory pathways generating immunosuppressive NKG2D ligands: New targets for therapeutic intervention.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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25 September 2018
Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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25 September 2018
NKG2D is a costimulatory receptor for human naive CD8+ T cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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25 September 2018
Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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25 September 2018
Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
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25 September 2018
Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
retrieved
25 September 2018
Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4457299
retrieved
7 December 2018
Cutting Edge: Down-Regulation of MICA on Human Tumors by Proteolytic Shedding
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26041808
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26041808
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/2326-6066.CIR-15-0098
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
PMCID
4457299
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
PubMed ID
26041808
1 reference
stated in
Europe PubMed Central
PubMed ID
26041808
retrieved
9 August 2017
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