(Q35688450)

9 August 2017

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title

Antifungal agents: in vitro susceptibility testing, pharmacodynamics, and prospects for combination therapy (English)

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9 August 2017

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Groll AH

1

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9 August 2017

Kolve H

series ordinal

2

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9 August 2017

publication date

11 March 2004

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European Journal of Clinical Microbiology & Infectious Diseases

9 August 2017

published in

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9 August 2017

volume

23

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9 August 2017

issue

4

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9 August 2017

page(s)

256-270

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https://scigraph.springernature.com/pub.10.1007/s10096-004-1108-6

9 August 2017

exact match

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cites work

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A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects.

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In vitro pharmacodynamic characteristics of flucytosine determined by time-kill methods

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Pharmacokinetics, excretion, and mass balance of liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate in humans

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In vitro activity of the echinocandin antifungal agent LY303,366 in comparison with itraconazole and amphotericin B against Aspergillus spp.

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Antifungal drug resistance in pathogenic fungi

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Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies

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Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia

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Early detection of aspergillus infection after allogeneic stem cell transplantation by polymerase chain reaction screening.

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Pharmacokinetic and pharmacodynamic modeling of anidulafungin (LY303366): reappraisal of its efficacy in neutropenic animal models of opportunistic mycoses using optimal plasma sampling

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In vitro testing of antimicrobial agents

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Novel triazole antifungal agents

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Itraconazole. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycoses

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Antifungal pharmacodynamics: concentration-effect relationships in vitro and in vivo

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In-vitro activity of voriconazole, itraconazole and amphotericin B against filamentous fungi

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Evolving role of flucytosine in immunocompromised patients: new insights into safety, pharmacokinetics, and antifungal therapy

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The postantifungal effect of 5-fluorocytosine on Candida albicans

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Activity of fluconazole: postantifungal effect, effects of low concentrations and of pretreatment on the susceptibility of Candida albicans to leucocytes

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12 December 2020

Characterization and quantitation of the pharmacodynamics of fluconazole in a neutropenic murine disseminated candidiasis infection model

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Organism-dependent fungicidal activities of azoles

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A coccidioidomycosis outbreak following the Northridge, Calif, earthquake

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Pharmacodynamics of fluconazole in a murine model of systemic candidiasis.

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Antifungal pharmacodynamic characteristics of fluconazole and amphotericin B against Cryptococcus neoformans

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Mode of Action of 5-Fluorocytosine and Mechanisms of Resistance

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12 December 2020

Combination therapy for aspergillosis: is it needed, and which combination?

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New drugs and novel targets for treatment of invasive fungal infections in patients with cancer

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Itraconazole for experimental pulmonary aspergillosis: comparison with amphotericin B, interaction with cyclosporin A, and correlation between therapeutic response and itraconazole concentrations in plasma

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Safety, tolerance, and pharmacokinetics of high-dose liposomal amphotericin B (AmBisome) in patients infected with Aspergillus species and other filamentous fungi: maximum tolerated dose study

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12 December 2020

Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.

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12 December 2020

The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro

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Antibiotics that inhibit fungal cell wall development

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12 December 2020

Antifungal efficacy, safety, and single-dose pharmacokinetics of LY303366, a novel echinocandin B, in experimental pulmonary aspergillosis in persistently neutropenic rabbits

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12 December 2020

In vitro susceptibilities of Candida bloodstream isolates to the new triazole antifungal agents BMS-207147, Sch 56592, and voriconazole

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12 December 2020

Antifungal resistance in pathogenic fungi

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12 December 2020

In vivo characterization of the pharmacodynamics of flucytosine in a neutropenic murine disseminated candidiasis model

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12 December 2020

Update on antifungals targeted to the cell wall: focus on beta-1,3-glucan synthase inhibitors

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12 December 2020

Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits

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Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandin

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12 December 2020

In vitro susceptibilities of Candida and Cryptococcus neoformans isolates from blood cultures of neutropenic patients.

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12 December 2020

Antifungal drug resistance of pathogenic fungi.

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12 December 2020

In vitro susceptibilities of clinical yeast isolates to a new echinocandin derivative, LY303366, and other antifungal agents.

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12 December 2020

Update: outbreak of acute febrile respiratory illness among college students--Acapulco, Mexico, March 2001.

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Clinical pharmacology of systemic antifungal agents: a comprehensive review of agents in clinical use, current investigational compounds, and putative targets for antifungal drug development

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12 December 2020

Growth medium effect on the antifungal activity of LY 303366

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12 December 2020

Activity of voriconazole: post-antifungal effect, effects of low concentrations and of pretreatment on the susceptibility of Candida albicans to leucocytes

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12 December 2020

Effect of fluconazole on viability of Candida albicans over extended periods of time

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12 December 2020

Antifungal activity of LY303366, a novel echinocandin B, in experimental disseminated candidiasis in rabbits

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12 December 2020

Dose-dependent pharmacokinetics of amphotericin B lipid complex in rabbits

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12 December 2020

Pharmacodynamics of amphotericin B in a neutropenic-mouse disseminated-candidiasis model

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12 December 2020

Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans

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12 December 2020

Comparative efficacy and distribution of lipid formulations of amphotericin B in experimental Candida albicans infection of the central nervous system

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12 December 2020

Correlation between in-vitro susceptibility testing to itraconazole and in-vivo outcome of Aspergillus fumigatus infection

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12 December 2020

Screening for circulating galactomannan as a noninvasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation recipients: a prospective validation.

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12 December 2020

Comparative evaluation of NCCLS M27-A and EUCAST broth microdilution procedures for antifungal susceptibility testing of candida species

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12 December 2020

Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome. National Institute of Allergy and Infectious Diseases Mycoses Study Group and AIDS Clinical Trials Group

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12 December 2020

Antifungal prophylaxis with itraconazole in prolonged neutropenia: correlation with plasma levels

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12 December 2020

Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.

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12 December 2020

Distinct patterns of gene expression associated with development of fluconazole resistance in serial candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis

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12 December 2020

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12 December 2020

In vivo pharmacodynamics of HMR 3270, a glucan synthase inhibitor, in a murine candidiasis model

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12 December 2020

Echinocandins: a new class of antifungal

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12 December 2020

Safety, plasma concentrations, and efficacy of high-dose fluconazole in invasive mold infections.

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12 December 2020

Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions

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12 December 2020

In vivo pharmacodynamics of antifungal drugs in treatment of candidiasis

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12 December 2020

Assessment of antifungal activities of fluconazole and amphotericin B administered alone and in combination against Candida albicans by using a dynamic in vitro mycotic infection model

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12 December 2020

Has antifungal susceptibility testing come of age?

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12 December 2020

Acquired itraconazole resistance in Aspergillus fumigatus

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12 December 2020

Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance P

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12 December 2020

Synergistic Action of Amphotericin B and 5-Fluorocytosine Against Yeast-Like Organisms

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12 December 2020

Refractory Aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin

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12 December 2020

Need for Alternative Trial Designs and Evaluation Strategies for Therapeutic Studies of Invasive Mycoses

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12 December 2020

In vitro efficacy and fungicidal activity of voriconazole against Aspergillus and Fusarium species

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12 December 2020

Pharmacodynamics of fluconazole, itraconazole, and amphotericin B against Candida albicans

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12 December 2020

Caspofungin in combination with itraconazole for the treatment of invasive aspergillosis in humans

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12 December 2020

Overview: antifungal combination therapy.

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12 December 2020

Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus.

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12 December 2020

Rationale for combination antifungal therapy

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12 December 2020

Fluconazole versus amphotericin B in the treatment of hematogenous candidiasis: a matched cohort study

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12 December 2020

Safety, tolerance, and pharmacokinetics of amphotericin B lipid complex in children with hepatosplenic candidiasis.

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12 December 2020

Compounds active against cell walls of medically important fungi

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12 December 2020

In vitro evaluation of various antifungal agents alone and in combination by using an automatic turbidimetric system combined with viable count determinations

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12 December 2020

In vivo pharmacokinetics and pharmacodynamics of a new triazole, voriconazole, in a murine candidiasis model.

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12 December 2020

In vivo pharmacodynamics of a new triazole, ravuconazole, in a murine candidiasis model

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12 December 2020

Fluconazole. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial and systemic mycoses

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12 December 2020

Liposomal and lipid formulations of amphotericin B. Clinical pharmacokinetics

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12 December 2020

Uncommon opportunistic fungi: new nosocomial threats

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12 December 2020

In vitro antifungal activity of BMS-207147 and itraconazole against yeast strains that are non-susceptible to fluconazole

1 reference

12 December 2020

Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole, and candida infections. Subcommittee on Antifungal Susceptibility Te

1 reference

12 December 2020

Amphotericin B: current understanding of mechanisms of action

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12 December 2020

Critical annotations to the use of azole antifungals for plant protection

1 reference

12 December 2020

A comparison of dynamic characteristics of fluconazole, itraconazole, and amphotericin B against Cryptococcus neoformans using time-kill methodology.

1 reference

12 December 2020

Experimental Trichosporon infection in persistently granulocytopenic rabbits: implications for pathogenesis, diagnosis, and treatment of an emerging opportunistic mycosis

1 reference

12 December 2020

Amphotericin B refractory aspergillosis after itraconazole: evidence for significant antagonism

1 reference

12 December 2020

Increasing volume and changing characteristics of invasive pulmonary aspergillosis on sequential thoracic computed tomography scans in patients with neutropenia

1 reference

12 December 2020

Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects

1 reference

12 December 2020

Pharmacokinetics, excretion, and mass balance of 14C after administration of 14C-cholesterol-labeled AmBisome to healthy volunteers

1 reference

12 December 2020

LY303366 exhibits rapid and potent fungicidal activity in flow cytometric assays of yeast viability

1 reference

12 December 2020

Lysis-centrifugation blood cultures in the detection of tissue-proven invasive candidiasis. Disseminated versus single-organ infection

1 reference

12 December 2020

Combination therapy of murine invasive candidiasis with fluconazole and amphotericin B.

1 reference

12 December 2020

In vitro activity of a new oral triazole, BMS-207147 (ER-30346)

1 reference

12 December 2020

Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis

1 reference

12 December 2020

Emerging targets for the development of novel antifungal therapeutics

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12 December 2020

Plasma protein binding of amphotericin B and pharmacokinetics of bound versus unbound amphotericin B after administration of intravenous liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate

1 reference

12 December 2020

Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis

1 reference

12 December 2020

A Comparison of Amphotericin B Alone and Combined with Flucytosine in the Treatment of Cryptoccal Meningitis

1 reference

12 December 2020

The genetic basis of fluconazole resistance development in Candida albicans

1 reference

12 December 2020

Antifungal pharmacodynamic characteristics of fluconazole and amphotericin B tested against Candida albicans.

1 reference

12 December 2020

In vitro pharmacodynamic properties of MK-0991 determined by time-kill methods

1 reference

12 December 2020

Safety, pharmacokinetics, and pharmacodynamics of cyclodextrin itraconazole in pediatric patients with oropharyngeal candidiasis

1 reference

12 December 2020

Interactions of itraconazole with amphotericin B in the treatment of murine invasive candidiasis

1 reference

12 December 2020

The postantibiotic effect of antifungal agents against common pathogenic yeasts

1 reference

12 December 2020

Concepts in design of comparative clinical trials of antifungal therapy in neutropenic patients

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12 December 2020

Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase

1 reference

12 December 2020

Trichosporon beigelii, an emerging pathogen resistant to amphotericin B

1 reference

12 December 2020

Comparison of In vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts

1 reference

12 December 2020

Lipid formulations of amphotericin B: clinical efficacy and toxicities

1 reference

12 December 2020

Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

1 reference

12 December 2020

10.1007/S10096-004-1108-6

Identifiers

DOI

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9 August 2017

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