(Q35692016)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

main subject

hemophilia

0 references

coagulation factor IX

0 references

0 references

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Amy D Shapiro

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Margaret V Ragni

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Leonard A Valentino

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Nigel S Key

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Neil C Josephson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jerry S Powell

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Gregory Cheng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Arthur R Thompson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jaya Goyal

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Karen L Tubridy

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Robert T Peters

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jennifer A Dumont

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Donald Euwart

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Lian Li

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Bengt Hallén

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Peter Gozzi

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Alan J Bitonti

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Alvin Luk

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Glenn F Pierce

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

22 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

666-672

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

Improvements in factor concentrates

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Half-life extension through albumin fusion technologies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Receptor-Fc fusion therapeutics, traps, and MIMETIBODY technology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Fusion-proteins as biopharmaceuticals--applications and challenges.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

FcRn: the neonatal Fc receptor comes of age.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Monomeric Fc fusions: impact on pharmacokinetic and biological activity of protein therapeutics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

A passionate kiss, then run: exocytosis and recycling of IgG by FcRn.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

A 6-year follow-up of dosing, coagulation factor levels and bleedings in relation to joint status in the prophylactic treatment of haemophilia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Update on treatment regimens: prophylaxis versus on-demand therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Prophylactic dosing of factor VIII and factor IX from a clinical pharmacokinetic perspective

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

The hemophilias--from royal genes to gene therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Mortality among males with hemophilia: relations with source of medical care. The Hemophilia Surveillance System Project Investigators.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Clinical evaluation of recombinant factor IX.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Nucleotide sequence of the gene for human factor IX (antihemophilic factor B)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Prolonged activity of factor IX as a monomeric Fc fusion protein

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Fixed dosing versus body size-based dosing of monoclonal antibodies in adult clinical trials

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Cutaneous wound healing is impaired in hemophilia B.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

The safety and efficacy of recombinant human blood coagulation factor IX in previously untreated patients with severe or moderately severe hemophilia B.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Issues surrounding therapeutic choices for hemophilia patients

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Prophylaxis in factor IX deficiency product and patient variation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Human recombinant factor IX: safety and efficacy studies in hemophilia B patients previously treated with plasma-derived factor IX concentrates

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Pharmacokinetics of recombinant factor IX in relation to age of the patient: implications for dosing in prophylaxis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Multidose pharmacokinetics of factor IX: implications for dosing in prophylaxis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265197

Variability of in vivo recovery of factor IX after infusion of monoclonal antibody purified factor IX concentrates in patients with hemophilia B. The Mononine Study Group

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22110246

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Haemophilia B: impact on patients and economic burden of disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22110246

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2011-07-367003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22110246%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

22110246

1 reference