(Q35694742)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26186535%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

An Extended Polyanion Activation Surface in Insulin Degrading Enzyme (English)

1 reference

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19 February 2020

2

1 reference

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19 February 2020

author name string

Eun Suk Song

1

1 reference

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19 February 2020

Tingting Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26186535%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Michael Sheetz

4

1 reference

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19 February 2020

David Lee

5

1 reference

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19 February 2020

Danny Tran

6

1 reference

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19 February 2020

Sheng Li

7

1 reference

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19 February 2020

Rajeev Prabhakar

8

1 reference

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19 February 2020

Louis B Hersh

9

1 reference

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19 February 2020

David W Rodgers

10

1 reference

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19 February 2020

language of work or name

English

0 references

publication date

17 July 2015

1 reference

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19 February 2020

1 reference

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19 February 2020

volume

10

1 reference

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19 February 2020

issue

7

1 reference

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19 February 2020

page(s)

e0133114

1 reference

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Creative Commons Attribution 4.0 International

19 February 2020

copyright license

start time

17 July 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Structural insights into fibrinogen dynamics using amide hydrogen/deuterium exchange mass spectrometry

1 reference

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Proteolytically inactive insulin-degrading enzyme inhibits amyloid formation yielding non-neurotoxic aβ peptide aggregates

27 July 2018

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Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation

27 July 2018

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Anion Activation Site of Insulin-degrading Enzyme

27 July 2018

1 reference

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Identification of the allosteric regulatory site of insulysin

27 July 2018

1 reference

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Mixed dimers of insulin-degrading enzyme reveal a cis activation mechanism

27 July 2018

1 reference

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A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties

27 July 2018

1 reference

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Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-α, and Amylin by Human Insulin-Degrading Enzyme

27 July 2018

1 reference

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Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

The insulysin (insulin degrading enzyme) enigma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Coot: model-building tools for molecular graphics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

ATP effects on insulin-degrading enzyme are mediated primarily through its triphosphate moiety

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Models@Home: distributed computing in bioinformatics using a screensaver based approach

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Analysis of the proteolysis of bioactive peptides using a peptidomics approach.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Insulin-degrading enzyme (IDE): a novel heat shock-like protein.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

25 September 2018

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Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506039

A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6

25 September 2018

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Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development.

25 September 2018

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Phosphorylation driven motions in the COOH-terminal Src kinase, CSK, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS).

25 September 2018

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Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme.

25 September 2018

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25 September 2018

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25 September 2018

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21 January 2018

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21 January 2018

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12 December 2020

Degradation of intraendosomal insulin by insulin-degrading enzyme without acidification

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12 December 2020

A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic proteinase

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12 December 2020

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26186535%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26186535%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26186535%20AND%20SRC:MED&resulttype=core&format=json